Dysfunctional connections between the nucleus and the actin and microtubule networks in laminopathic models.
about
Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffoldsApproaches to manipulating the dimensionality and physicochemical properties of common cellular scaffoldsRhoGTPases as key players in mammalian cell adaptation to microgravityPlectin isoform 1-dependent nuclear docking of desmin networks affects myonuclear architecture and expression of mechanotransducers.Nuclear motility in glioma cells reveals a cell-line dependent role of various cytoskeletal componentsLINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retinaDynamic modeling of cell migration and spreading behaviors on fibronectin coated planar substrates and micropatterned geometriesStructural insights into SUN-KASH complexes across the nuclear envelopeImplications and Assessment of the Elastic Behavior of Lamins in LaminopathiesLamin A variants that cause striated muscle disease are defective in anchoring transmembrane actin-associated nuclear lines for nuclear movement.The interaction between nesprins and sun proteins at the nuclear envelope is critical for force transmission between the nucleus and cytoskeleton.Emerin organizes actin flow for nuclear movement and centrosome orientation in migrating fibroblasts.Alpha-actinin and filamin cooperatively enhance the stiffness of actin filament networks.Emergence of a prestressed eukaryotic nucleus during cellular differentiation and developmentAttenuated hypertrophic response to pressure overload in a lamin A/C haploinsufficiency mouseActomyosin tension exerted on the nucleus through nesprin-1 connections influences endothelial cell adhesion, migration, and cyclic strain-induced reorientation.Lamin A/C and emerin regulate MKL1-SRF activity by modulating actin dynamicsFunctional coupling between the extracellular matrix and nuclear lamina by Wnt signaling in progeria.The differential formation of the LINC-mediated perinuclear actin cap in pluripotent and somatic cells.LINC complexes in health and disease.Nuclear deformability constitutes a rate-limiting step during cell migration in 3-D environmentsNucleoskeleton mechanics at a glanceCellular mechanosensing: getting to the nucleus of it all.Structural protein 4.1R is integrally involved in nuclear envelope protein localization, centrosome-nucleus association and transcriptional signaling.Nuclear envelope in nuclear positioning and cell migrationHigh-throughput ballistic injection nanorheology to measure cell mechanicsTargeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.Energetics, epigenetics, mitochondrial genetics.SMRT analysis of MTOC and nuclear positioning reveals the role of EB1 and LIC1 in single-cell polarization.The physics of cancer: the role of physical interactions and mechanical forces in metastasis.Lamins at a glance.The Cardiomyopathy Lamin A/C D192G Mutation Disrupts Whole-Cell Biomechanics in Cardiomyocytes as Measured by Atomic Force Microscopy Loading-Unloading Curve Analysis.The nuclear envelope protein Nesprin-2 has roles in cell proliferation and differentiation during wound healing.Keeping the LINC: the importance of nucleocytoskeletal coupling in intracellular force transmission and cellular function.The cellular mastermind(?)-mechanotransduction and the nucleus.Nuclear mechanics in cancerNuclear mechanics in diseaseMechanics of the nucleus.Altered chromatin organization and SUN2 localization in mandibuloacral dysplasia are rescued by drug treatment.Mechanical regulation of nuclear structure and function.
P2860
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P2860
Dysfunctional connections between the nucleus and the actin and microtubule networks in laminopathic models.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Dysfunctional connections betw ...... tworks in laminopathic models.
@en
type
label
Dysfunctional connections betw ...... tworks in laminopathic models.
@en
prefLabel
Dysfunctional connections betw ...... tworks in laminopathic models.
@en
P2093
P2860
P1433
P1476
Dysfunctional connections betw ...... etworks in laminopathic models
@en
P2093
Arun L Shrestha
Colin L Stewart
Denis Wirtz
Didier Hodzic
Lidia Hernandez
P J Stewart-Hutchinson
Shyam B Khatau
P2860
P304
P356
10.1529/BIOPHYSJ.108.139428
P407
P577
2008-09-12T00:00:00Z