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Regulation of motor neuron specification by phosphorylation of neurogenin 2

Regulation of motor neuron specification by phosphorylation of neurogenin 2

http://www.wikidata.org/entity/Q36983419

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Critical role of PI3K/Akt/GSK3β in motoneuron specification from human neural stem cells in response to FGF2 and EGF Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling Her6 regulates the neurogenetic gradient and neuronal identity in the thalamus Directing astroglia from the cerebral cortex into subtype specific functional neurons Phosphorylation regulates OLIG2 cofactor choice and the motor neuron-oligodendrocyte fate switch A novel function of the proneural factor Ascl1 in progenitor proliferation identified by genome-wide characterization of its targets Small Molecules Modulate Chromatin Accessibility to Promote NEUROG2-Mediated Fibroblast-to-Neuron Reprogramming GSK-3: Functional Insights from Cell Biology and Animal Models.ERK5 MAP kinase regulates neurogenin1 during cortical neurogenesis.Akt regulates the expression of MafK, synaptotagmin I, and syntenin-1, which play roles in neuronal function.An amino terminal phosphorylation motif regulates intranuclear compartmentalization of Olig2 in neural progenitor cells.Stem cell-derived motor neurons: applications and challenges in amyotrophic lateral sclerosis.Dynamin I phosphorylation by GSK3 controls activity-dependent bulk endocytosis of synaptic vesicles.Established monolayer differentiation of mouse embryonic stem cells generates heterogeneous neocortical-like neurons stalled at a stage equivalent to midcorticogenesis.Neurogenin 2 mediates amyloid-β precursor protein-stimulated neurogenesis.Context dependence of proneural bHLH proteins.What Are the bona fide GSK3 Substrates?NeuroD factors regulate cell fate and neurite stratification in the developing retina.Cell cycle-regulated multi-site phosphorylation of Neurogenin 2 coordinates cell cycling with differentiation during neurogenesis Neurogenin2 regulates the initial axon guidance of cortical pyramidal neurons projecting medially to the corpus callosum.Phosphorylation in intrinsically disordered regions regulates the activity of Neurogenin2.Roles of p53 and p27(Kip1) in the regulation of neurogenesis in the murine adult subventricular zone Role of fibroblast growth factor receptors in astrocytic stem cells Multi-site phosphorylation regulates NeuroD4 activity during primary neurogenesis: a conserved mechanism amongst proneural proteins.Post-translational modification of Ngn2 differentially affects transcription of distinct targets to regulate the balance between progenitor maintenance and differentiation.Regulation of locomotion and motoneuron trajectory selection and targeting by the Drosophila homolog of Olig family transcription factors.Human Induced Pluripotent Stem Cell NEUROG2 Dual Knockin Reporter Lines Generated by the CRISPR/Cas9 System.Phosphorylated olig1 localizes to the cytosol of oligodendrocytes and promotes membrane expansion and maturation.Rapid Ngn2-induction of excitatory neurons from hiPSC-derived neural progenitor cells.Selective induction of neocortical GABAergic neurons by the PDK1-Akt pathway through activation of Mash1.Small molecules enable neurogenin 2 to efficiently convert human fibroblasts into cholinergic neurons.Transcriptional Networks Controlled by NKX2-1 in the Development of Forebrain GABAergic Neurons.GSK3 signalling in neural development.Generating spinal motor neuron diversity: a long quest for neuronal identity.Cell cycle regulation of proliferation versus differentiation in the central nervous system.Characterization of human neural differentiation from pluripotent stem cells using proteomics/PTMomics--current state-of-the-art and challenges.bHLH proteins involved in Drosophila neurogenesis are mutually regulated at the level of stability Notch signaling regulates motor neuron differentiation of human embryonic stem cells.Transcriptional regulatory events initiated by Ascl1 and Neurog2 during neuronal differentiation of P19 embryonic carcinoma cells.Role for Lhx2 in corticogenesis through regulation of progenitor differentiation.

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Regulation of motor neuron specification by phosphorylation of neurogenin 2

http://www.wikidata.org/entity/Q36983419

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Regulation of motor neuron specification by phosphorylation of neurogenin 2

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Regulation of motor neuron specification by phosphorylation of neurogenin 2

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J.NEURON.2008.01.037

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Regulation of motor neuron specification by phosphorylation of neurogenin 2

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Hsin-Yi Henry Ho

http://www.w3.org/2001/XMLSchema#string

Janine Zieg

http://www.w3.org/2001/XMLSchema#string

Jin P Park

http://www.w3.org/2001/XMLSchema#string

Linda Hu

http://www.w3.org/2001/XMLSchema#string

Martin V Kurtev

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Mi-Ryoung Song

http://www.w3.org/2001/XMLSchema#string

Michael E Greenberg

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Qiufu Ma

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Samuel L Pfaff

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Yong-Chao Ma

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P2860

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

Phosphorylation of nuclear MyoD is required for its rapid degradation.

Ssdp proteins interact with the LIM-domain-binding protein Ldb1 to regulate development

Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in neuronal development

GSK-3: tricks of the trade for a multi-tasking kinase

The Wnt signaling pathway in development and disease

Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms

Phosphorylated CREB binds specifically to the nuclear protein CBP

Requirement for the homeobox gene Hb9 in the consolidation of motor neuron identity

Development of the mesencephalic dopaminergic neuron system is compromised in the absence of neurogenin 2

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phosphorylation

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