Silibinin inhibits cytokine-induced signaling cascades and down-regulates inducible nitric oxide synthase in human lung carcinoma A549 cells.
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Molecular mechanisms of silibinin-mediated cancer chemoprevention with major emphasis on prostate cancerChemopreventive and anti-cancer efficacy of silibinin against growth and progression of lung cancerSilibinin attenuates sulfur mustard analog-induced skin injury by targeting multiple pathways connecting oxidative stress and inflammationSilibinin can induce differentiation as well as enhance vitamin D3-induced differentiation of human AML cells ex vivo and regulates the levels of differentiation-related transcription factors.Silibinin inhibits human nonsmall cell lung cancer cell growth through cell-cycle arrest by modulating expression and function of key cell-cycle regulatorsSilybin and the liver: from basic research to clinical practice.The ameliorative effect of silibinin against radiation-induced lung injury: protection of normal tissue without decreasing therapeutic efficacy in lung cancer.Silibinin and its 2,3-dehydro-derivative inhibit basal cell carcinoma growth via suppression of mitogenic signaling and transcription factors activation.Silibinin down-regulates FAT10 and modulate TNF-α/IFN-γ-induced chromosomal instability and apoptosis sensitivity.Concurrent Treatment with Taxifolin and Cilostazol on the Lowering of β-Amyloid Accumulation and Neurotoxicity via the Suppression of P-JAK2/P-STAT3/NF-κB/BACE1 Signaling Pathways.Targeting tumor microenvironment with silibinin: promise and potential for a translational cancer chemopreventive strategy.Antimetastatic efficacy of silibinin: molecular mechanisms and therapeutic potential against cancer.Effects of flavonoids and other polyphenols on inflammation.Beneficial effects of the naturally occurring flavonoid silibinin on the prostate cancer microenvironment: role of monocyte chemotactic protein-1 and immune cell recruitment.Silibinin: a potential old drug for cancer therapy.Silibinin strongly inhibits the growth kinetics of colon cancer stem cell-enriched spheroids by modulating interleukin 4/6-mediated survival signals.Quercetin and EGCG exhibit chemopreventive effects in cholangiocarcinoma cells via suppression of JAK/STAT signaling pathway.Silibinin reverses drug resistance in human small-cell lung carcinoma cells.Epigenetic modifications and p21-cyclin B1 nexus in anticancer effect of histone deacetylase inhibitors in combination with silibinin on non-small cell lung cancer cells.Effect of silibinin in human colorectal cancer cells: targeting the activation of NF-κB signaling.Silibinin modulates TNF-α and IFN-γ mediated signaling to regulate COX2 and iNOS expression in tumorigenic mouse lung epithelial LM2 cells.Silibinin suppresses spontaneous tumorigenesis in APC min/+ mouse model by modulating beta-catenin pathway.Silibinin prevents lung tumorigenesis in wild-type but not in iNOS-/- mice: potential of real-time micro-CT in lung cancer chemoprevention studies.Silibinin Inhibits Neutrophilic Inflammation and Mucus Secretion Induced by Cigarette Smoke via Suppression of ERK-SP1 Pathway.
P2860
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P2860
Silibinin inhibits cytokine-induced signaling cascades and down-regulates inducible nitric oxide synthase in human lung carcinoma A549 cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Silibinin inhibits cytokine-in ...... man lung carcinoma A549 cells.
@en
type
label
Silibinin inhibits cytokine-in ...... man lung carcinoma A549 cells.
@en
prefLabel
Silibinin inhibits cytokine-in ...... man lung carcinoma A549 cells.
@en
P2093
P2860
P1476
Silibinin inhibits cytokine-in ...... man lung carcinoma A549 cells.
@en
P2093
Chapla Agarwal
Gagan Deep
Manesh Chittezhath
Rajesh Agarwal
Rana P Singh
P2860
P304
P356
10.1158/1535-7163.MCT-08-0256
P577
2008-07-01T00:00:00Z