about
Broad-spectrum antiviral therapeuticsDirect activation of protein kinases by unanchored polyubiquitin chainsPathogen recognition and inflammatory signaling in innate immune defensesFrameshifting RNA pseudoknots: structure and mechanismStress granules in the viral replication cycleSensing viral RNAs by Dicer/RIG-I like ATPases across speciesProtein kinase PKR and RNA adenosine deaminase ADAR1: new roles for old players as modulators of the interferon responseAn evolutionary perspective on the broad antiviral specificity of MxAInfluenza B virus ribonucleoprotein is a potent activator of the antiviral kinase PKRMacrophage-expressed IFN-β contributes to apoptotic alveolar epithelial cell injury in severe influenza virus pneumoniaTick-borne flaviviruses: dissecting host immune responses and virus countermeasuresEnhancement of replication of RNA viruses by ADAR1 via RNA editing and inhibition of RNA-activated protein kinaseInnate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasomeHepatitis C virus controls interferon production through PKR activationMumps Virus Induces Protein-Kinase-R-Dependent Stress Granules, Partly Suppressing Type III Interferon Production.eIF2alpha Phosphorylation-dependent translation in CA1 pyramidal cells impairs hippocampal memory consolidation without affecting general translation.Andes virus nucleocapsid protein interrupts protein kinase R dimerization to counteract host interference in viral protein synthesis.Mechanisms of protein kinase PKR-mediated amplification of beta interferon induction by C protein-deficient measles virusHuman Herpesvirus 6A Exhibits Restrictive Propagation with Limited Activation of the Protein Kinase R-eIF2α Stress Pathway.PKR mediated regulation of inflammation and IL-10 during viral encephalomyelitis.Role of PKR and Type I IFNs in viral control during primary and secondary infection.Induction of stress granules by interferon and down-regulation by the cellular RNA adenosine deaminase ADAR1.Innate immunity to influenza virus infection.Hematopoietic cell kinase associates with the 40S ribosomal subunit and mediates the ribotoxic stress response to deoxynivalenol in mononuclear phagocytes.Tipping the balance: antagonism of PKR kinase and ADAR1 deaminase functions by virus gene products.A Toll-like receptor-responsive kinase, protein kinase R, is inactivated in endotoxin tolerance through differential K63/K48 ubiquitination.Both transcriptional regulation and translational control of ATF4 are central to the integrated stress response.Glycine 184 in nonstructural protein NS1 determines the virulence of influenza A virus strain PR8 without affecting the host interferon response.Transcriptional and epigenetic substrates of methamphetamine addiction and withdrawal: evidence from a long-access self-administration model in the rat.Roles of vaccinia virus genes E3L and K3L and host genes PKR and RNase L during intratracheal infection of C57BL/6 mice.Protein kinase regulated by dsRNA downregulates the interferon production in dengue virus- and dsRNA-stimulated human lung epithelial cellsNative tertiary structure and nucleoside modifications suppress tRNA's intrinsic ability to activate the innate immune sensor PKR.RNAi induces innate immunity through multiple cellular signaling pathways.Regulation of innate immunity through RNA structure and the protein kinase PKR.Direct activation of ribosome-associated double-stranded RNA-dependent protein kinase (PKR) by deoxynivalenol, anisomycin and ricin: a new model for ribotoxic stress response inductionShared signatures between rheumatoid arthritis, systemic lupus erythematosus and Sjögren's syndrome uncovered through gene expression meta-analysis.HIV-1 replication and the cellular eukaryotic translation apparatusAdaptive gene amplification as an intermediate step in the expansion of virus host range.Protein kinase R as mediator of the effects of interferon (IFN) gamma and tumor necrosis factor (TNF) alpha on normal and dysplastic hematopoiesisThe cellular RNA helicase UAP56 is required for prevention of double-stranded RNA formation during influenza A virus infection
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Structure and function of the protein kinase R.
@en
type
label
Structure and function of the protein kinase R.
@en
prefLabel
Structure and function of the protein kinase R.
@en
P1476
Structure and function of the protein kinase R
@en
P2093
B R G Williams
P304
P356
10.1007/978-3-540-71329-6_13
P577
2007-01-01T00:00:00Z