about
New approaches to the treatment of orphan genetic disorders: Mitigating molecular pathologies using chemicalsOptimizing the design of oligonucleotides for homology directed gene targeting.The position of DNA cleavage by TALENs and cell synchronization influences the frequency of gene editing directed by single-stranded oligonucleotidesSimultaneous targeted exchange of two nucleotides by single-stranded oligonucleotides clusters within a region of about fourteen nucleotides.PCRless library mutagenesis via oligonucleotide recombination in yeastRecA-independent single-stranded DNA oligonucleotide-mediated mutagenesis.Regulation of Gene Editing Activity Directed by Single-Stranded Oligonucleotides and CRISPR/Cas9 Systems.Modified bases enable high-efficiency oligonucleotide-mediated allelic replacement via mismatch repair evasion.The myotubularin family of lipid phosphatases in disease and in spermatogenesisEfficient Gene Editing in Pluripotent Stem Cells by Bacterial Injection of Transcription Activator-Like Effector Nuclease ProteinsInsertional Mutagenesis by CRISPR/Cas9 Ribonucleoprotein Gene Editing in Cells Targeted for Point Mutation Repair Directed by Short Single-Stranded DNA Oligonucleotides.Proliferation of genetically modified human cells on electrospun nanofiber scaffolds.Analyses of point mutation repair and allelic heterogeneity generated by CRISPR/Cas9 and single-stranded DNA oligonucleotides.The Development of TALE Nucleases for Biotechnology.An update on targeted gene repair in mammalian cells: methods and mechanismsOligonucleotide-directed gene-editing technology: mechanisms and future prospects.Treatment options for lysosomal storage disorders: developing insights.Enhanced gene repair mediated by methyl-CpG-modified single-stranded oligonucleotidesOligonucleotide-mediated gene editing is underestimated in cells expressing mutated green fluorescent protein and is positively associated with target protein expression.DNA breakage associated with targeted gene alteration directed by DNA oligonucleotides.Transplantation of gene-corrected motor neurons as a therapeutic strategy for spinal muscular atrophy.Combinatorial gene editing in mammalian cells using ssODNs and TALENs.Strand bias influences the mechanism of gene editing directed by single-stranded DNA oligonucleotides.DNA damage response pathway and replication fork stress during oligonucleotide directed gene editing.Validation of oligonucleotide-mediated gene editing.Genetic modification through oligonucleotide-mediated mutagenesis. A GMO regulatory challenge?Efficient Delivery and Nuclear Uptake Is Not Sufficient to Detect Gene Editing in CD34+ Cells Directed by a Ribonucleoprotein Complex.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Progress and prospects: targeted gene alteration (TGA).
@en
type
label
Progress and prospects: targeted gene alteration (TGA).
@en
prefLabel
Progress and prospects: targeted gene alteration (TGA).
@en
P2860
P356
P1433
P1476
Progress and prospects: targeted gene alteration (TGA).
@en
P2093
Parekh-Olmedo H
P2860
P2888
P304
P356
10.1038/SJ.GT.3303053
P577
2007-11-01T00:00:00Z