Lineage tracing reveals multipotent stem cells maintain human adenomas and the pattern of clonal expansion in tumor evolution.
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Cancer Evolution and the Limits of Predictability in Precision Cancer MedicineEvolutionary determinants of cancerStem cell competition in the gut: insights from multi-scale computational modellingOvarian cancer stem cells: are they real and why are they important?Cell lineage tracing in human epithelial tissues using mitochondrial DNA mutations as clonal markers.Glioblastoma stem cells (GSCs) epigenetic plasticity and interconversion between differentiated non-GSCs and GSCs.Paneth Cell-Rich Regions Separated by a Cluster of Lgr5+ Cells Initiate Crypt Fission in the Intestinal Stem Cell Niche.A Big Bang model of human colorectal tumor growth.Many private mutations originate from the first few divisions of a human colorectal adenoma.Loss of Hes1 Differentiates Sessile Serrated Adenoma/Polyp From Hyperplastic Polyp.Cancer stem cells in glioma: challenges and opportunities.Autoimmunity as a double agent in tumor killing and cancer promotion.Quality assurance in clinical trials--the role of pathology.Cancer Stem Cells: Plasticity Works against Therapy.Molecular evolution of colorectal cancer: from multistep carcinogenesis to the big bang.The Complex, Clonal, and Controversial Nature of Barrett's Esophagus.Catch my drift? Making sense of genomic intra-tumour heterogeneity.Molecular classification of gastric cancer.Treatment-Induced Mutagenesis and Selective Pressures Sculpt Cancer Evolution.Evolution of Premalignant Disease.New insights into the earliest stages of colorectal tumorigenesis.Subclonal diversity arises early even in small colorectal tumours and contributes to differential growth fates.Mutational Heterogeneity in APC and KRAS Arises at the Crypt Level and Leads to Polyclonality in Early Colorectal Tumorigenesis.Characterization of LGR5 stem cells in colorectal adenomas and carcinomas.An individual based computational model of intestinal crypt fission and its application to predicting unrestrictive growth of the intestinal epithelium.The stem cell organisation, and the proliferative and gene expression profile of Barrett's epithelium, replicates pyloric-type gastric glandsThe destruction complex of beta-catenin in colorectal carcinoma and colonic adenoma.Spatial constraints govern competition of mutant clones in human epidermis.BitPhylogeny: a probabilistic framework for reconstructing intra-tumor phylogenies.Neuroblastoma pathogenesis: deregulation of embryonic neural crest development.Paneth cells in intestinal physiology and pathophysiology.Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution.Multicolor lineage tracing reveals clonal architecture and dynamics in colon cancer.Logarithmic expansion of LGR5+ cells in human colorectal cancer.Colorectal cancer: genetic abnormalities, tumor progression, tumor heterogeneity, clonal evolution and tumor-initiating cells.The confounding effects of tumour heterogeneity and cellular plasticity on personalized surgical management of colorectal cancer
P2860
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P2860
Lineage tracing reveals multipotent stem cells maintain human adenomas and the pattern of clonal expansion in tumor evolution.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Lineage tracing reveals multip ...... expansion in tumor evolution.
@en
type
label
Lineage tracing reveals multip ...... expansion in tumor evolution.
@en
prefLabel
Lineage tracing reveals multip ...... expansion in tumor evolution.
@en
P2093
P2860
P50
P356
P1476
Lineage tracing reveals multip ...... l expansion in tumor evolution
@en
P2093
Adam Humphries
Alice Gutteridge
George Elia
Laura J Gay
Marco R Novelli
Richard Poulsom
Rosemary Jeffery
P2860
P304
P356
10.1073/PNAS.1220353110
P407
P577
2013-06-13T00:00:00Z