Inhibition of apurinic/apyrimidinic endonuclease I's redox activity revisited. - Wikidata - wikimedia - TriplyDB

Inhibition of apurinic/apyrimidinic endonuclease I's redox activity revisited.

Inhibition of apurinic/apyrimidinic endonuclease I's redox activity revisited.

http://www.wikidata.org/entity/Q36996445

about

APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functions Role of the DNA base excision repair protein, APE1 in cisplatin, oxaliplatin, or carboplatin induced sensory neuropathy High-resolution crystal structures reveal plasticity in the metal binding site of apurinic/apyrimidinic endonuclease I.Applications of hydrogen/deuterium exchange MS from 2012 to 2014.Apurinic/apyrimidinic endonuclease/redox factor-1 (APE1/Ref-1) redox function negatively regulates NRF2.The redox function of APE1 is involved in the differentiation process of stem cells toward a neuronal cell fate.Inhibition of APE1/Ref-1 redox activity rescues human retinal pigment epithelial cells from oxidative stress and reduces choroidal neovascularization.Small molecule activation of apurinic/apyrimidinic endonuclease 1 reduces DNA damage induced by cisplatin in cultured sensory neurons An APE1 inhibitor reveals critical roles of the redox function of APE1 in KSHV replication and pathogenic phenotypes Human apurinic/apyrimidinic endonuclease 1.Regulation of HIF1α under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual Targeting in Patient-Derived 3D Pancreatic Cancer Models.Identification and Characterization of New Chemical Entities Targeting Apurinic/Apyrimidinic Endonuclease 1 for the Prevention of Chemotherapy-Induced Peripheral Neuropathy Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.Structure-activity studies of peptidomimetics based on kinase-inhibitory region of suppressors of cytokine signaling 1.The APE1 redox inhibitor E3330 reduces collective cell migration of human breast cancer cells and decreases chemoinvasion and colony formation when combined with docetaxel.A Suite of "Minimalist" Photo-Crosslinkers for Live-Cell Imaging and Chemical Proteomics: Case Study with BRD4 Inhibitors.APE1/Ref-1 redox-specific inhibition decreases survivin protein levels and induces cell cycle arrest in prostate cancer cells.Exploiting the Ref-1-APE1 node in cancer signaling and other diseases: from bench to clinic.Unilateral ureteral obstruction induces DNA repair by APE1.Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival

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Inhibition of apurinic/apyrimidinic endonuclease I's redox activity revisited.

http://www.wikidata.org/entity/Q36996445

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

@zh-mo

2013年論文

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2013年论文

@wuu

2013年论文

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2013年论文

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name

Inhibition of apurinic/apyrimidinic endonuclease I's redox activity revisited.

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type

label

Inhibition of apurinic/apyrimidinic endonuclease I's redox activity revisited.

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Inhibition of apurinic/apyrimidinic endonuclease I's redox activity revisited.

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Inhibition of apurinic/apyrimidinic endonuclease I's redox activity revisited.

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April Reed

http://www.w3.org/2001/XMLSchema#string

Daniela Marasco

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Derek Logsdon

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Jun Zhang

http://www.w3.org/2001/XMLSchema#string

Kaice A LaFavers

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Mark R Kelley

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Meihua Luo

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Michael L Gross

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Qiujia Chen

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P2860

Thioredoxin nuclear translocation and interaction with redox factor-1 activates the activator protein-1 transcription factor in response to ionizing radiation

Two divalent metal ions in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1: implications for the catalytic mechanism

Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes

Identification and characterization of mitochondrial targeting sequence of human apurinic/apyrimidinic endonuclease 1

Identification of redox/repair protein Ref-1 as a potent activator of p53

APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process.

Isolation of a small molecule inhibitor of DNA base excision repair.

Activation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP

Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease

Identification and characterization of inhibitors of human apurinic/apyrimidinic endonuclease APE1

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2955-2966

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10.1021/BI400179M

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17

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52

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Millie M. Georgiadis

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2013-04-18T00:00:00Z

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23597102

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3706204

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