Bi-directional heterologous desensitization between the major HIV-1 co-receptor CXCR4 and the kappa-opioid receptor
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Opioids and Viral Infections: A Double-Edged SwordMorphine increases brain levels of ferritin heavy chain leading to inhibition of CXCR4-mediated survival signaling in neuronsNeuronal ferritin heavy chain and drug abuse affect HIV-associated cognitive dysfunction.Cross-desensitization of CCR1, but not CCR2, following activation of the formyl peptide receptor FPR1.Increasingly accurate dynamic molecular models of G-protein coupled receptor oligomers: Panacea or Pandora's box for novel drug discovery?Autoantibodies to the delta-opioid receptor function as opioid agonists and display immunomodulatory activityConsequences of ChemR23 heteromerization with the chemokine receptors CXCR4 and CCR7.Interactions of HIV and drugs of abuse: the importance of glia, neural progenitors, and host genetic factors.Progress in elucidating the structural and dynamic character of G Protein-Coupled Receptor oligomers for use in drug discovery.Activation of cannabinoid type 2 receptors inhibits HIV-1 envelope glycoprotein gp120-induced synapse loss.Morphine and gp120 toxic interactions in striatal neurons are dependent on HIV-1 strain.Biological Significance of GPCR Heteromerization in the Neuro-Endocrine SystemPolymorphisms of the kappa opioid receptor and prodynorphin genes: HIV risk and HIV natural history.Regulation of neuronal ferritin heavy chain, a new player in opiate-induced chemokine dysfunctionModulation of chemokine receptor activity through dimerization and crosstalkPertussis toxin signals through the TCR to initiate cross-desensitization of the chemokine receptor CXCR4.Neurocognitive and neuroinflammatory correlates of PDYN and OPRK1 mRNA expression in the anterior cingulate in postmortem brain of HIV-infected subjects.Molecular signatures of mu opioid receptor and somatostatin receptor 2 in pancreatic cancer.Differential expression of the alternatively spliced OPRM1 isoform μ-opioid receptor-1K in HIV-infected individuals.Activated niacin receptor HCA2 inhibits chemoattractant-mediated macrophage migration via Gβγ/PKC/ERK1/2 pathway and heterologous receptor desensitization.Immunomodulatory properties of kappa opioids and synthetic cannabinoids in HIV-1 neuropathogenesis.Mechanisms regulating chemokine receptor activity.Surgical management of apical pelvic support defects: the impact of robotic technology.Functions of the chemokine receptor CXCR4 in the central nervous system and its regulation by μ-opioid receptors.Opioid and chemokine receptor crosstalk: a promising target for pain therapy?The orexin 1 receptor modulates kappa opioid receptor function via a JNK-dependent mechanism.Dopamine D2 and serotonin 5-HT1A receptor interaction in the context of the effects of antipsychotics - in vitro studies.Chemokines and Their Receptors Are Key Players in the Orchestra That Regulates Wound Healing.
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P2860
Bi-directional heterologous desensitization between the major HIV-1 co-receptor CXCR4 and the kappa-opioid receptor
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 03 June 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Bi-directional heterologous de ...... and the kappa-opioid receptor
@en
Bi-directional heterologous de ...... and the kappa-opioid receptor.
@nl
type
label
Bi-directional heterologous de ...... and the kappa-opioid receptor
@en
Bi-directional heterologous de ...... and the kappa-opioid receptor.
@nl
prefLabel
Bi-directional heterologous de ...... and the kappa-opioid receptor
@en
Bi-directional heterologous de ...... and the kappa-opioid receptor.
@nl
P2093
P2860
P1476
Bi-directional heterologous de ...... and the kappa-opioid receptor
@en
P2093
Ellen B Geller
Lily Zhang
Martin W Adler
Matthew J Finley
Penny Davey
Thomas J Rogers
Xiaohong Chen
P2860
P304
P356
10.1016/J.JNEUROIM.2008.04.021
P577
2008-06-03T00:00:00Z