Altered spectrin dimer-dimer association and instability of erythrocyte membrane skeletons in hereditary pyropoikilocytosis
about
Headpiece domain of dematin is required for the stability of the erythrocyte membranePoint mutation in the beta-spectrin gene associated with alpha I/74 hereditary elliptocytosis. Implications for the mechanism of spectrin dimer self-associationFour different mutations in codon 28 of alpha spectrin are associated with structurally and functionally abnormal spectrin alpha I/74 in hereditary elliptocytosisMultiple protein 4.1 isoforms produced by alternative splicing in human erythroid cellsErythroid expression of the human alpha-spectrin gene promoter is mediated by GATA-1- and NF-E2-binding proteinsMolecular defect in the membrane skeleton of blood bank-stored red cells. Abnormal spectrin-protein 4.1-actin complex formation.Growth of Plasmodium falciparum in human erythrocytes containing abnormal membrane proteins.Sequences downstream of the erythroid promoter are required for high level expression of the human alpha-spectrin gene.Regulation of protein mobility in cell membranes: a dynamic corral model.A novel mobile element inserted in the alpha spectrin gene: spectrin dayton. A truncated alpha spectrin associated with hereditary elliptocytosis.The spectrin network as a barrier to lateral diffusion in erythrocytes. A percolation analysis.Molecular defect in the sickle erythrocyte skeleton. Abnormal spectrin binding to sickle inside-our vesiclesModulation of erythrocyte membrane material properties by Ca2+ and calmodulin. Implications for their role in regulation of skeletal protein interactions.Membrane protein lesions in erythrocytes with Heinz bodiesDefective binding of spectrin to ankyrin in a kindred with recessively inherited hereditary elliptocytosisMolecular basis of spectrin deficiency in beta spectrin Durham. A deletion within beta spectrin adjacent to the ankyrin-binding site precludes spectrin attachment to the membrane in hereditary spherocytosis.Restoration of normal membrane stability to unstable protein 4.1-deficient erythrocyte membranes by incorporation of purified protein 4.1.Erythrocyte membrane deformability and stability: two distinct membrane properties that are independently regulated by skeletal protein associations.Visualization of the hexagonal lattice in the erythrocyte membrane skeleton.Drosophila development requires spectrin network formation.Defective spectrin dimer-dimer association with hereditary elliptocytosisSpectrin beta-chain variant associated with hereditary elliptocytosis.Molecular defect of spectrin in hereditary pyropoikilocytosis. Alterations in the trypsin-resistant domain involved in spectrin self-association.Missing band 7 membrane protein in two patients with high Na, low K erythrocytes.Molecular and functional changes in spectrin from patients with hereditary pyropoikilocytosis.Gene disruption of dematin causes precipitous loss of erythrocyte membrane stability and severe hemolytic anemiaCombination of two mutant alpha spectrin alleles underlies a severe spherocytic hemolytic anemiaEvaluation of red cell membrane cytoskeletal disorders using a flow cytometric method in South iran.Computational Biomechanics of Human Red Blood Cells in Hematological Disorders.The cytoskeletal system of red blood cells.The spectrin membrane skeleton of normal and abnormal human erythrocytes: a review.Influence of lateral association on forced unfolding of antiparallel spectrin heterodimers.
P2860
Q24531210-5A80DEA9-8B94-4695-9520-0AFEA8C8EA35Q24618688-2636A5C7-37C8-488F-B354-6DEA86209197Q24632040-328605E7-46DE-4F78-BFA7-985052CA0EDBQ24644272-67E8B350-3B26-4402-8192-5F6E2CCD2AA1Q28219123-C2E68242-FC3D-4326-A10F-0B8871073D36Q33460269-A4427E16-AA3B-4D98-B821-E5ADA951DF36Q33808075-3351DF23-4CD5-41F9-B996-FB65BF1E910AQ33981947-DFA4DB64-7B4D-4CF1-94F7-CBB27AC0B657Q34172134-D56DAACB-1B6E-4592-91F8-BFB37D712725Q34228966-600407E4-2068-4EB2-85DC-261FD792C872Q34261053-C3D289CB-F178-4069-A4AB-1BFBEB54215FQ34524564-23E687B6-8531-4453-B7F5-25EE39CB3967Q34558832-82D938DC-69AD-43E5-BCC7-9755B648D373Q34563040-31D60066-B2FF-4CAC-9865-970CD7E55D6CQ34613301-B9B9255A-BC75-4954-8002-BC9E4336AB91Q35767774-F929C067-319E-4A12-ADEA-117A32E78364Q35807798-58F44A3A-4D12-402C-9F02-AD3C8FD08E65Q36213132-09385B6D-49EA-4198-AB0D-9823D26ECEB4Q36216490-380881D6-D1A3-4352-BCF8-A9096AA9CAB1Q36235170-3FB879A9-7EFF-4508-A04C-96EF43928666Q36288322-BE7CC715-CF7F-4FA8-B023-767499614D40Q36986594-4497DA4F-34BE-408F-985B-47ABCB9BB8BEQ36987699-CFABE013-F559-4472-B265-39136E791BE4Q36988676-66570465-211B-4FAD-B268-87DF6F73708FQ36990592-F84F56C4-A488-4214-B60D-2A1AB8A10DCDQ37076428-D72D9263-C09B-4510-86E9-3A63A681AD00Q37361483-1DB04FB9-C491-4DFD-AEC4-6DCBA519ACFDQ38914499-F4732D42-BEF1-4789-A2E6-9FA3C59694C0Q38998761-6984DDEB-C2C9-454A-8911-5B2C437D0847Q39476776-088F70ED-A606-4A5E-9FE5-D4CC913B7D7CQ40145857-B4CDA88D-497F-413B-AD9D-896266F2E3BFQ51715102-99511F4D-EB4D-46CB-A5AC-90C4E9E05EB3
P2860
Altered spectrin dimer-dimer association and instability of erythrocyte membrane skeletons in hereditary pyropoikilocytosis
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 1981
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Altered spectrin dimer-dimer a ...... hereditary pyropoikilocytosis
@en
Altered spectrin dimer-dimer a ...... hereditary pyropoikilocytosis.
@nl
type
label
Altered spectrin dimer-dimer a ...... hereditary pyropoikilocytosis
@en
Altered spectrin dimer-dimer a ...... hereditary pyropoikilocytosis.
@nl
prefLabel
Altered spectrin dimer-dimer a ...... hereditary pyropoikilocytosis
@en
Altered spectrin dimer-dimer a ...... hereditary pyropoikilocytosis.
@nl
P2093
P2860
P356
P1476
Altered spectrin dimer-dimer a ...... hereditary pyropoikilocytosis
@en
P2093
P2860
P304
P356
10.1172/JCI110293
P407
P577
1981-09-01T00:00:00Z