ERK-mediated regulation of leukotriene biosynthesis by androgens: a molecular basis for gender differences in inflammation and asthma
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Indirubin-3'-monoxime exerts a dual mode of inhibition towards leukotriene-mediated vascular smooth muscle cell migrationSex-specific association of depression and a haplotype in leukotriene A4 hydrolase geneEmerging Comorbidities in Adult Asthma: Risks, Clinical Associations, and MechanismsEstrogen Signaling Modulates Allergic Inflammation and Contributes to Sex Differences in AsthmaPhenotypes, Risk Factors, and Mechanisms of Adult-Onset AsthmaConversion of human 5-lipoxygenase to a 15-lipoxygenase by a point mutation to mimic phosphorylation at Serine-663Factors influencing the eicosanoids synthesis in vivoA review on leukotrienes and their receptors with reference to asthmaVariable expression of cysteinyl leukotriene type I receptor splice variants in asthmatic females with different promoter haplotypes.Sex differences in prostaglandin biosynthesis in neutrophils during acute inflammationRoles of coactosin-like protein (CLP) and 5-lipoxygenase-activating protein (FLAP) in cellular leukotriene biosynthesisKnockout of 5-lipoxygenase results in age-dependent anxiety-like behavior in female mice.Gender-specific asthma treatment.Pharmacophore modeling and virtual screening for novel acidic inhibitors of microsomal prostaglandin E₂ synthase-1 (mPGES-1)Sex hormones in allergic conjunctivitis: altered levels of circulating androgens and estrogens in children and adolescents with vernal keratoconjunctivitis.Association between circulating levels of sex steroid hormones and Barrett's esophagus in men: a case-control analysis.Caulerpenyne and related bis-enol esters are novel-type inhibitors of human 5-lipoxygenase.2-(4-(Biphenyl-4-ylamino)-6-chloropyrimidin-2-ylthio)octanoic acid (HZ52)--a novel type of 5-lipoxygenase inhibitor with favourable molecular pharmacology and efficacy in vivoMale gender bias in autism and pediatric autoimmunityPancreatic functions in high salt fed female rats17β Estradiol Modulates Perfusion Pressure and Expression of 5-LOX and CYP450 4A in the Isolated Kidney of Metabolic Syndrome Female Rats.Androgen receptor influences on body defense system via modulation of innate and adaptive immune systems: lessons from conditional AR knockout mice.Adipokines and Cysteinyl Leukotrienes in the Pathogenesis of AsthmaOxylipid Profile of Low-Dose Aspirin Exposure: A Pharmacometabolomics Study5-Lipoxygenase: mechanisms of regulation.Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice.Monocyte/macrophage androgen receptor suppresses cutaneous wound healing in mice by enhancing local TNF-alpha expression.Accelerated resolution of inflammation underlies sex differences in inflammatory responses in humans.Perinatal bisphenol A exposures increase production of pro-inflammatory mediators in bone marrow-derived mast cells of adult mice.5-Lipoxygenase inhibitors: a review of recent developments and patents.Immunopharmacological role of the leukotriene receptor antagonists and inhibitors of leukotrienes generating enzymes in multiple sclerosis.5-Lipoxygenase inhibitors: a review of recent patents (2010-2012).Leukotriene receptor antagonists pranlukast and montelukast for treating asthma.Leukotrienes and sex: strange bedfellows?Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males.Elucidation of the molecular mechanism and the efficacy in vivo of a novel 1,4-benzoquinone that inhibits 5-lipoxygenase.Novel leukotriene biosynthesis inhibitors (2012-2016) as anti-inflammatory agents.Reconstitution of anti-allergic activities of PG102 derived from Actinidia arguta by combining synthetic chemical compounds.Coactosin-like protein functions as a stabilizing chaperone for 5-lipoxygenase: role of tryptophan 102.The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP).
P2860
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P2860
ERK-mediated regulation of leukotriene biosynthesis by androgens: a molecular basis for gender differences in inflammation and asthma
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 08 December 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
ERK-mediated regulation of leu ...... ces in inflammation and asthma
@en
ERK-mediated regulation of leu ...... es in inflammation and asthma.
@nl
type
label
ERK-mediated regulation of leu ...... ces in inflammation and asthma
@en
ERK-mediated regulation of leu ...... es in inflammation and asthma.
@nl
prefLabel
ERK-mediated regulation of leu ...... ces in inflammation and asthma
@en
ERK-mediated regulation of leu ...... es in inflammation and asthma.
@nl
P2093
P2860
P50
P356
P1476
ERK-mediated regulation of leu ...... ces in inflammation and asthma
@en
P2093
Antonietta Rossi
Barbara Lawrenz
Bengt Samuelsson
Carlo Pergola
Eva Neunhoeffer
Gabriele Dodt
P2860
P304
19881-19886
P356
10.1073/PNAS.0809120105
P407
P577
2008-12-08T00:00:00Z