ERK-mediated regulation of leukotriene biosynthesis by androgens: a molecular basis for gender differences in inflammation and asthma - Wikidata - wikimedia - TriplyDB

ERK-mediated regulation of leukotriene biosynthesis by androgens: a molecular basis for gender differences in inflammation and asthma

ERK-mediated regulation of leukotriene biosynthesis by androgens: a molecular basis for gender differences in inflammation and asthma

http://www.wikidata.org/entity/Q37003847

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Indirubin-3'-monoxime exerts a dual mode of inhibition towards leukotriene-mediated vascular smooth muscle cell migration Sex-specific association of depression and a haplotype in leukotriene A4 hydrolase gene Emerging Comorbidities in Adult Asthma: Risks, Clinical Associations, and Mechanisms Estrogen Signaling Modulates Allergic Inflammation and Contributes to Sex Differences in Asthma Phenotypes, Risk Factors, and Mechanisms of Adult-Onset Asthma Conversion of human 5-lipoxygenase to a 15-lipoxygenase by a point mutation to mimic phosphorylation at Serine-663 Factors influencing the eicosanoids synthesis in vivo A review on leukotrienes and their receptors with reference to asthma Variable expression of cysteinyl leukotriene type I receptor splice variants in asthmatic females with different promoter haplotypes.Sex differences in prostaglandin biosynthesis in neutrophils during acute inflammation Roles of coactosin-like protein (CLP) and 5-lipoxygenase-activating protein (FLAP) in cellular leukotriene biosynthesis Knockout of 5-lipoxygenase results in age-dependent anxiety-like behavior in female mice.Gender-specific asthma treatment.Pharmacophore modeling and virtual screening for novel acidic inhibitors of microsomal prostaglandin E₂ synthase-1 (mPGES-1)Sex hormones in allergic conjunctivitis: altered levels of circulating androgens and estrogens in children and adolescents with vernal keratoconjunctivitis.Association between circulating levels of sex steroid hormones and Barrett's esophagus in men: a case-control analysis.Caulerpenyne and related bis-enol esters are novel-type inhibitors of human 5-lipoxygenase.2-(4-(Biphenyl-4-ylamino)-6-chloropyrimidin-2-ylthio)octanoic acid (HZ52)--a novel type of 5-lipoxygenase inhibitor with favourable molecular pharmacology and efficacy in vivo Male gender bias in autism and pediatric autoimmunity Pancreatic functions in high salt fed female rats 17β Estradiol Modulates Perfusion Pressure and Expression of 5-LOX and CYP450 4A in the Isolated Kidney of Metabolic Syndrome Female Rats.Androgen receptor influences on body defense system via modulation of innate and adaptive immune systems: lessons from conditional AR knockout mice.Adipokines and Cysteinyl Leukotrienes in the Pathogenesis of Asthma Oxylipid Profile of Low-Dose Aspirin Exposure: A Pharmacometabolomics Study 5-Lipoxygenase: mechanisms of regulation.Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice.Monocyte/macrophage androgen receptor suppresses cutaneous wound healing in mice by enhancing local TNF-alpha expression.Accelerated resolution of inflammation underlies sex differences in inflammatory responses in humans.Perinatal bisphenol A exposures increase production of pro-inflammatory mediators in bone marrow-derived mast cells of adult mice.5-Lipoxygenase inhibitors: a review of recent developments and patents.Immunopharmacological role of the leukotriene receptor antagonists and inhibitors of leukotrienes generating enzymes in multiple sclerosis.5-Lipoxygenase inhibitors: a review of recent patents (2010-2012).Leukotriene receptor antagonists pranlukast and montelukast for treating asthma.Leukotrienes and sex: strange bedfellows?Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males.Elucidation of the molecular mechanism and the efficacy in vivo of a novel 1,4-benzoquinone that inhibits 5-lipoxygenase.Novel leukotriene biosynthesis inhibitors (2012-2016) as anti-inflammatory agents.Reconstitution of anti-allergic activities of PG102 derived from Actinidia arguta by combining synthetic chemical compounds.Coactosin-like protein functions as a stabilizing chaperone for 5-lipoxygenase: role of tryptophan 102.The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP).

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ERK-mediated regulation of leukotriene biosynthesis by androgens: a molecular basis for gender differences in inflammation and asthma

http://www.wikidata.org/entity/Q37003847

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scientific article published on 08 December 2008

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ERK-mediated regulation of leu ...... ces in inflammation and asthma

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ERK-mediated regulation of leu ...... es in inflammation and asthma.

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ERK-mediated regulation of leu ...... ces in inflammation and asthma

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ERK-mediated regulation of leu ...... es in inflammation and asthma.

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ERK-mediated regulation of leu ...... ces in inflammation and asthma

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ERK-mediated regulation of leu ...... es in inflammation and asthma.

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PNAS.0809120105

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Proceedings of the National Academy of Sciences of the United States of America

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ERK-mediated regulation of leu ...... ces in inflammation and asthma

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Antonietta Rossi

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Barbara Lawrenz

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Bengt Samuelsson

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Carlo Pergola

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Eva Neunhoeffer

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Gabriele Dodt

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P2860

Arachidonic acid metabolism in polymorphonuclear leukocytes: effects of ionophore A23187

Coactosin-like protein supports 5-lipoxygenase enzyme activity and up-regulates leukotriene A4 production

Translocation of 5-lipoxygenase to the membrane in human leukocytes challenged with ionophore A23187

Rapid import of cytosolic 5-lipoxygenase into the nucleus of neutrophils after in vivo recruitment and in vitro adherence

5-lipoxygenase is phosphorylated by p38 kinase-dependent MAPKAP kinases

Capacity for repeatable leukotriene generation after transient stimulation of mast cells and macrophages

Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production

Functional testosterone receptors in plasma membranes of T cells.

The neutrophil: function and regulation in innate and humoral immunity.

Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation.

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10.1073/PNAS.0809120105

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50

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