T-bet plays a key role in NK-mediated control of melanoma metastatic disease
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T-bet and Eomesodermin in NK Cell Development, Maturation, and FunctionLinking obesity with type 2 diabetes: the role of T-betNicotinic receptor β2 determines NK cell-dependent metastasis in a murine model of metastatic lung cancer.The role of the Th1 transcription factor T-bet in a mouse model of immune-mediated bone-marrow failureCharacterization of T-bet and eomes in peripheral human immune cellsTranscription factor Foxo1 is a negative regulator of natural killer cell maturation and functionIntracellular osteopontin regulates homeostasis and function of natural killer cells.Intralesional delivery of dendritic cells engineered to express T-bet promotes protective type 1 immunity and the normalization of the tumor microenvironment.The aged nonhematopoietic environment impairs natural killer cell maturation and function.Association between gastric cancer and -1993 polymorphism of TBX21 gene.The TBX21 transcription factor T-1993C polymorphism is associated with decreased IFN-γ and IL-4 production by primary human lymphocytes.Rapid development of exhaustion and down-regulation of eomesodermin limit the antitumor activity of adoptively transferred murine natural killer cells.Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection.Anti-inflammatory activity of p-coumaryl alcohol-gamma-O-methyl ether is mediated through modulation of interferon-gamma production in Th cells.T-bet-deficient NOD mice are protected from diabetes due to defects in both T cell and innate immune system function.Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells.Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sitesCommon themes emerge in the transcriptional control of T helper and developmental cell fate decisions regulated by the T-box, GATA and ROR families.Transcriptional regulation of the mucosal immune system mediated by T-bet.The 'T-cell-ness' of NK cells: unexpected similarities between NK cells and T cells.T-bet in disease.Transcriptional control of natural killer cell differentiation and function.Transcription factors involved in the regulation of natural killer cell development and function: an update.Higher numbers of T-bet(+) intratumoral lymphoid cells correlate with better survival in gastric cancer.Immunosurveillance of lung melanoma metastasis in EBI-3-deficient mice mediated by CD8+ T cells.Differential effects of low-dose decitabine on immune effector and suppressor responses in melanoma-bearing mice.T-cell-mediated tumor immune surveillance and expression of B7 co-inhibitory molecules in cancers of the upper gastrointestinal tract.KLRG1+ natural killer cells protect against pulmonary metastatic disease by immunosurveillance.Anti-proliferative Activity of T-bet.Complement Receptor 3 Has Negative Impact on Tumor Surveillance through Suppression of Natural Killer Cell Function.A role for T-bet-mediated tumour immune surveillance in anti-IL-17A treatment of lung cancer.Oncogenes in immune cells as potential therapeutic targets.In vivo tumor suppression activity by T cell-specific T-bet restoration.The Notch Signaling Pathway Is Balancing Type 1 Innate Lymphoid Cell Immune Functions.Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function
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P2860
T-bet plays a key role in NK-mediated control of melanoma metastatic disease
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on June 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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T-bet plays a key role in NK-mediated control of melanoma metastatic disease
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T-bet plays a key role in NK-mediated control of melanoma metastatic disease.
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T-bet plays a key role in NK-mediated control of melanoma metastatic disease
@en
T-bet plays a key role in NK-mediated control of melanoma metastatic disease.
@nl
prefLabel
T-bet plays a key role in NK-mediated control of melanoma metastatic disease
@en
T-bet plays a key role in NK-mediated control of melanoma metastatic disease.
@nl
P2093
P2860
P1476
T-bet plays a key role in NK-mediated control of melanoma metastatic disease
@en
P2093
Eun Sook Hwang
Harvey Cantor
Laurie H Glimcher
Miriam B F Werneck
P2860
P304
P356
10.4049/JIMMUNOL.180.12.8004
P407
P577
2008-06-01T00:00:00Z