Probing the transient dark state of substrate binding to GroEL by relaxation-based solution NMR
about
Seeing the invisible by paramagnetic and diamagnetic NMRIntrinsic unfoldase/foldase activity of the chaperonin GroEL directly demonstrated using multinuclear relaxation-based NMR.Recent excitements in protein NMR: Large proteins and biologically relevant dynamics.Rapid Determination of Fast Protein Dynamics from NMR Chemical Exchange Saturation Transfer DataVisualizing transient dark states by NMR spectroscopy.Role of denatured-state properties in chaperonin action probed by single-molecule spectroscopyFairy "tails": flexibility and function of intrinsically disordered extensions in the photosynthetic world.Characterizing methyl-bearing side chain contacts and dynamics mediating amyloid β protofibril interactions using ¹³C(methyl)-DEST and lifetime line broadening.The molecular mechanism of nuclear transport revealed by atomic-scale measurements.Subunit conformational variation within individual GroEL oligomers resolved by Cryo-EM.Protein dynamics and function from solution state NMR spectroscopy.Digested disorder: Quarterly intrinsic disorder digest (July-August-September, 2013)Conformational recognition of an intrinsically disordered protein.ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain.Global Dynamics and Exchange Kinetics of a Protein on the Surface of Nanoparticles Revealed by Relaxation-Based Solution NMR Spectroscopy.Chaperonin GroEL accelerates protofibril formation and decorates fibrils of the Het-s prion protein.Mechanistic Insight into Nanoparticle Surface Adsorption by Solution NMR Spectroscopy in an Aqueous Gel.Binding kinetics and substrate selectivity in HIV-1 protease-Gag interactions probed at atomic resolution by chemical exchange NMR.Structural Mapping of a Chaperone-Substrate Interaction SurfaceStructural Mapping of a Chaperone-Substrate Interaction SurfaceRapid Determination of Fast Protein Dynamics from NMR Chemical Exchange Saturation Transfer Data
P2860
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P2860
Probing the transient dark state of substrate binding to GroEL by relaxation-based solution NMR
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 24 June 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Probing the transient dark sta ...... relaxation-based solution NMR
@en
Probing the transient dark sta ...... relaxation-based solution NMR.
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type
label
Probing the transient dark sta ...... relaxation-based solution NMR
@en
Probing the transient dark sta ...... relaxation-based solution NMR.
@nl
prefLabel
Probing the transient dark sta ...... relaxation-based solution NMR
@en
Probing the transient dark sta ...... relaxation-based solution NMR.
@nl
P2093
P2860
P356
P1476
Probing the transient dark sta ...... relaxation-based solution NMR
@en
P2093
David S Libich
G Marius Clore
Jinfa Ying
Nicolas L Fawzi
P2860
P304
11361-11366
P356
10.1073/PNAS.1305715110
P407
P577
2013-06-24T00:00:00Z