CYP2D6 polymorphism: implications for antipsychotic drug response, schizophrenia and personality traits.
about
Psychedelic 5-methoxy-N,N-dimethyltryptamine: metabolism, pharmacokinetics, drug interactions, and pharmacological actionsCytochrome P450-mediated drug metabolism in the brainDecreased hippocampal volume and increased anxiety in a transgenic mouse model expressing the human CYP2C19 gene.Oxidation of the endogenous cannabinoid arachidonoyl ethanolamide by the cytochrome P450 monooxygenases: physiological and pharmacological implications.Cytochrome P450 mediates dopamine formation in the brain in vivo.Pharmacogenomics of drug-metabolizing enzymes: a recent update on clinical implications and endogenous effects.The endocannabinoid anandamide is a substrate for the human polymorphic cytochrome P450 2D6.Novel drug metabolism indices for pharmacogenetic functional status based on combinatory genotyping of CYP2C9, CYP2C19 and CYP2D6 genes.Perturbation of mitiglinide metabolism by chronic unpredicted mild stress in rats.CYP2D6 variation, behaviour and psychopathology: implications for pharmacogenomics-guided clinical trialsGenetic variation in CYP3A43 is associated with response to antipsychotic medication.Second generation antipsychotic-induced obsessive-compulsive symptoms in schizophrenia: a review of the experimental literature.Psychiatry meets pharmacogenetics for the treatment of revolving door patients with psychiatric disorders.Pharmacogenetics of neurological and psychiatric diseases at older age: has the time come?Molecular diversity at the CYP2D6 locus in healthy and schizophrenic southern Brazilians.Marmoset cytochrome P450 2D8 in livers and small intestines metabolizes typical human P450 2D6 substrates, metoprolol, bufuralol and dextromethorphan.Brain drug-metabolizing cytochrome P450 enzymes are active in vivo, demonstrated by mechanism-based enzyme inhibition.Current and potential pharmacological and psychosocial interventions for anxiety symptoms and disorders in patients with schizophrenia: structured review.Relation between CYP2D6 phenotype and genotype and personality in healthy volunteers.Use of pharmacogenetics in bioequivalence studies to reduce sample size: an example with mirtazapine and CYP2D6.CYP2D6 in the brain: genotype effects on resting brain perfusion.Relation between CYP2D6 genotype, personality, neurocognition and overall psychopathology in healthy volunteers.Xenobiotic metabolizing and transporter genes: gene-gene interactions in schizophrenia and related disorders.
P2860
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P2860
CYP2D6 polymorphism: implications for antipsychotic drug response, schizophrenia and personality traits.
description
2007 nî lūn-bûn
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2007年の論文
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2007年学术文章
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2007年学术文章
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2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
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2007年學術文章
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2007年學術文章
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name
CYP2D6 polymorphism: implicati ...... hrenia and personality traits.
@en
CYP2D6 polymorphism: implicati ...... hrenia and personality traits.
@nl
type
label
CYP2D6 polymorphism: implicati ...... hrenia and personality traits.
@en
CYP2D6 polymorphism: implicati ...... hrenia and personality traits.
@nl
prefLabel
CYP2D6 polymorphism: implicati ...... hrenia and personality traits.
@en
CYP2D6 polymorphism: implicati ...... hrenia and personality traits.
@nl
P2093
P2860
P1433
P1476
CYP2D6 polymorphism: implicati ...... hrenia and personality traits.
@en
P2093
Adrián Llerena
Eva M Peñas-Lledó
P2860
P304
P356
10.2217/14622416.8.11.1597
P50
P577
2007-11-01T00:00:00Z