A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis
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Etrolizumab for induction of remission in ulcerative colitisEtrolizumab for induction of remission in ulcerative colitisThe clinical potential of etrolizumab in ulcerative colitis: hypes and hopesAdvances in the development of new biologics in inflammatory bowel diseaseIntegrin-based therapeutics: biological basis, clinical use and new drugsHepatic manifestations of non-steroidal inflammatory bowel disease therapyPromising biological therapies for ulcerative colitis: A review of the literatureMedical Therapy of Active Ulcerative ColitisInflammatory Bowel Disease: An Overview of Immune Mechanisms and Biological TreatmentsReview article: anti-adhesion therapies for inflammatory bowel diseaseEfficacy and safety of antiintegrin antibody for inflammatory bowel disease: a systematic review and meta-analysisReceptor occupancy assessment by flow cytometry as a pharmacodynamic biomarker in biopharmaceutical developmentAssessment of Disease-Related Therapeutic Protein Drug-Drug Interaction for Etrolizumab in Patients With Moderately to Severely Active Ulcerative ColitisDifferential effects of α4β7 and GPR15 on homing of effector and regulatory T cells from patients with UC to the inflamed gut in vivo.Etrolizumab for ulcerative colitis: the new kid on the block?New strategies for treatment of inflammatory bowel diseaseSystematic Review and Meta-analysis: Placebo Rates in Induction and Maintenance Trials of Ulcerative Colitis.Pharmacology of AMG 181, a human anti-α4 β7 antibody that specifically alters trafficking of gut-homing T cells.Leukocyte traffic blockade as a therapeutic strategy in inflammatory bowel disease.Animal models of ulcerative colitis and their application in drug research.Evaluation of assay interference and interpretation of CXCR4 receptor occupancy results in a preclinical study with MEDI3185, a fully human antibody to CXCR4The value of experimental models of colitis in predicting efficacy of biological therapies for inflammatory bowel diseases.Integrin modulators: a patent review.T-cell trafficking and anti-adhesion strategies in inflammatory bowel disease: current and future prospects.Novel concepts in inflammatory bowel disease.Vedolizumab for the treatment of ulcerative colitis.Blockade of lymphocyte trafficking in inflammatory bowel diseases therapy: importance of specificity of endothelial target.Targeting integrins and adhesion molecules to combat inflammatory bowel disease.New targeted therapies such as anti-adhesion molecules, anti-IL-12/23 and anti-Janus kinases are looking toward a more effective treatment of inflammatory bowel disease.Efficacy and Safety of Natalizumab and Vedolizumab for the Management of Crohn's Disease: A Systematic Review and Meta-analysis.Systematic review and meta-analysis: opportunistic infections and malignancies during treatment with anti-integrin antibodies in inflammatory bowel disease.The unusual suspects--innate lymphoid cells as novel therapeutic targets in IBD.Emerging therapeutic targets and strategies in Crohn's disease.Integrin antagonists as potential therapeutic options for the treatment of Crohn's disease.Novel Insights into the Mechanisms of Gut Homing and Antiadhesion Therapies in Inflammatory Bowel Diseases.αEβ7 Integrin Identifies Subsets of Pro-Inflammatory Colonic CD4+ T Lymphocytes in Ulcerative Colitis.Update on the Use of Biologic Therapy in Ulcerative Colitis.Emerging treatments for ulcerative colitis: a systematic review.Frontiers in Drug Research and Development for Inflammatory Bowel Disease.Infection risk with biologic therapy in patients with inflammatory bowel disease.
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P2860
A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 20 June 2012
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
A randomised phase I study of ...... e to severe ulcerative colitis
@en
A randomised phase I study of etrolizumab
@nl
type
label
A randomised phase I study of ...... e to severe ulcerative colitis
@en
A randomised phase I study of etrolizumab
@nl
prefLabel
A randomised phase I study of ...... e to severe ulcerative colitis
@en
A randomised phase I study of etrolizumab
@nl
P2093
P2860
P1433
P1476
A randomised phase I study of ...... e to severe ulcerative colitis
@en
P2093
Andreas Sturm
Brian Bressler
Daan W Hommes
Daniel C Baumgart
Diana Luca
Dimitri Danilenko
Jackson Egen
Jennifer Visich
John C Mansfield
Marna Williams
P2860
P304
P356
10.1136/GUTJNL-2011-301769
P407
P577
2012-06-20T00:00:00Z