Activation of the mammalian target of rapamycin complex 1 is both necessary and sufficient to stimulate eukaryotic initiation factor 2Bvarepsilon mRNA translation and protein synthesis.
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Glucocorticoids induce senescence in primary human tenocytes by inhibition of sirtuin 1 and activation of the p53/p21 pathway: in vivo and in vitro evidence.mTORC1-independent reduction of retinal protein synthesis in type 1 diabetes.Control of translation initiation through integration of signals generated by hormones, nutrients, and exerciseSimvastatin represses protein synthesis in the muscle-derived C₂C₁₂ cell line with a concomitant reduction in eukaryotic initiation factor 2B expressionERK and Akt signaling pathways function through parallel mechanisms to promote mTORC1 signalingIdentification of ubiquitin-modified lysine residues and novel phosphorylation sites on eukaryotic initiation factor 2B epsilonEffects of chronic overload on muscle hypertrophy and mTOR signaling in young adult and aged rats.Muscle hypertrophy is associated with increases in proteasome activity that is independent of MuRF1 and MAFbx expression.Recent progress toward understanding the molecular mechanisms that regulate skeletal muscle mass.The role of mTORC1 in regulating protein synthesis and skeletal muscle mass in response to various mechanical stimuli.Chronic high fat feeding attenuates load-induced hypertrophy in mice.Eukaryotic initiation factor 2B epsilon induces cap-dependent translation and skeletal muscle hypertrophy.
P2860
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P2860
Activation of the mammalian target of rapamycin complex 1 is both necessary and sufficient to stimulate eukaryotic initiation factor 2Bvarepsilon mRNA translation and protein synthesis.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 15 May 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Activation of the mammalian ta ...... slation and protein synthesis.
@en
Activation of the mammalian ta ...... slation and protein synthesis.
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type
label
Activation of the mammalian ta ...... slation and protein synthesis.
@en
Activation of the mammalian ta ...... slation and protein synthesis.
@nl
prefLabel
Activation of the mammalian ta ...... slation and protein synthesis.
@en
Activation of the mammalian ta ...... slation and protein synthesis.
@nl
P2093
P2860
P1476
Activation of the mammalian ta ...... slation and protein synthesis.
@en
P2093
James W Gallagher
Jamie L Crispino
Leonard S Jefferson
Neil Kubica
Scot R Kimball
P2860
P304
P356
10.1016/J.BIOCEL.2008.04.010
P577
2008-05-15T00:00:00Z