Molecular pathobiology of gastrointestinal stromal sarcomas.
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Tumor-intrinsic and -extrinsic roles of c-Kit: mast cells as the primary off-target of tyrosine kinase inhibitorsCell signaling by receptor tyrosine kinasesTargeting gastrointestinal stromal tumors: the role of regorafenibImmune Effects of Chemotherapy, Radiation, and Targeted Therapy and Opportunities for Combination With ImmunotherapyMolecular Technologies in the Clinical Diagnostic LaboratoryZNF-mediated resistance to imatinib mesylate in gastrointestinal stromal tumorGenetic aberrations in imatinib-resistant dermatofibrosarcoma protuberans revealed by whole genome sequencingStrategies for modern biomarker and drug development in oncology.Clinical outcomes of patients with advanced gastrointestinal stromal tumors: safety and efficacy in a worldwide treatment-use trial of sunitinib.Detection of treatment-induced changes in signaling pathways in gastrointestinal stromal tumors using transcriptomic data.Phase I clinical trial of combination imatinib and ipilimumab in patients with advanced malignanciesChromosome copy number changes carry prognostic information independent of KIT/PDGFRA point mutations in gastrointestinal stromal tumorsGastrointestinal stromal tumor and its targeted therapeutics.Involvement of c-KIT mutation in the development of gastrointestinal stromal tumors through proliferation promotion and apoptosis inhibitionTumor heterogeneity: causes and consequencesComplete longitudinal analyses of the randomized, placebo-controlled, phase III trial of sunitinib in patients with gastrointestinal stromal tumor following imatinib failure.Clinical and molecular characteristics of gastrointestinal stromal tumors in the pediatric and young adult populationGene expression signatures and response to imatinib mesylate in gastrointestinal stromal tumor.Molecular pathology of sarcomas: concepts and clinical implicationsHigh density DNA array analysis reveals distinct genomic profiles in a subset of gastrointestinal stromal tumorsA phase I study of single-agent nilotinib or in combination with imatinib in patients with imatinib-resistant gastrointestinal stromal tumors.Optimizing adherence to adjuvant imatinib in gastrointestinal stromal tumor.Frequent KIT mutations in human gastrointestinal stromal tumors.Practical aspects of risk assessment in gastrointestinal stromal tumors.Drug repurposing identifies a synergistic combination therapy with imatinib mesylate for gastrointestinal stromal tumor.The epidemiology and pathogenesis of neoplasia in the small intestine.New fronts in the adjuvant treatment of GIST.GEIS 2013 guidelines for gastrointestinal sarcomas (GIST)Gastrointestinal stromal tumors, somatic mutations and candidate genetic risk variantsMTOR inhibition enhances NVP-AUY922-induced autophagy-mediated KIT degradation and cytotoxicity in imatinib-resistant gastrointestinal stromal tumors.Imatinib as the first and only treatment in Europe for adult patients at significant risk of relapse following gastrointestinal stromal tumor removal.Response to imatinib rechallenge in a patient with a recurrent gastrointestinal stromal tumor after adjuvant therapy: a case reportCarney triad, SDH-deficient tumors, and Sdhb+/- mice share abnormal mitochondriaTowards global consensus in the treatment of gastrointestinal stromal tumorTumor heterogeneity: mechanisms and bases for a reliable application of molecular marker designCorrelation of KIT and PDGFRA mutational status with clinical benefit in patients with gastrointestinal stromal tumor treated with sunitinib in a worldwide treatment-use trial.Pathology of gastrointestinal stromal tumors.Clinical outcomes of patients with gastrointestinal stromal tumor in phase I clinical trials.Precise probes of type II interferon activity define the origin of interferon signatures in target tissues in rheumatic diseases.Inpatient burden of gastrointestinal stromal tumors in the United States.
P2860
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P2860
Molecular pathobiology of gastrointestinal stromal sarcomas.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Molecular pathobiology of gastrointestinal stromal sarcomas.
@en
Molecular pathobiology of gastrointestinal stromal sarcomas.
@nl
type
label
Molecular pathobiology of gastrointestinal stromal sarcomas.
@en
Molecular pathobiology of gastrointestinal stromal sarcomas.
@nl
prefLabel
Molecular pathobiology of gastrointestinal stromal sarcomas.
@en
Molecular pathobiology of gastrointestinal stromal sarcomas.
@nl
P1476
Molecular pathobiology of gastrointestinal stromal sarcomas
@en
P2093
Christopher L Corless
P304
P356
10.1146/ANNUREV.PATHMECHDIS.3.121806.151538
P577
2008-01-01T00:00:00Z