In vitro and in vivo anti-tumor activity of miR-221/222 inhibitors in multiple myeloma. - Wikidata - wikimedia - TriplyDB

In vitro and in vivo anti-tumor activity of miR-221/222 inhibitors in multiple myeloma.

In vitro and in vivo anti-tumor activity of miR-221/222 inhibitors in multiple myeloma.

http://www.wikidata.org/entity/Q37016562

about

MicroRNAs: Novel Crossroads between Myeloma Cells and the Bone Marrow Microenvironment MicroRNAs in multiple myeloma and related bone disease MicroRNAs in B-cells: from normal differentiation to treatment of malignancies Implications of biomarkers in human hepatocellular carcinoma pathogenesis and therapy Role of microRNAs in hepatocellular carcinoma: a clinical perspective Towards Stratified Medicine in Plasma Cell Myeloma MicroRNA: important player in the pathobiology of multiple myeloma PDK1 inhibitor GSK2334470 exerts antitumor activity in multiple myeloma and forms a novel multitargeted combination with dual mTORC1/C2 inhibitor PP242 Targeting of multiple myeloma-related angiogenesis by miR-199a-5p mimics: in vitro and in vivo anti-tumor activity.miR-221/222 control luminal breast cancer tumor progression by regulating different targets.Prognostic value of miR-221-3p, miR-342-3p and miR-491-5p expression in colon cancer Platelet-derived growth factor primes cancer-associated fibroblasts for apoptosis.PLC-beta 1 regulates the expression of miR-210 during mithramycin-mediated erythroid differentiation in K562 cells Targeting miR-21 inhibits in vitro and in vivo multiple myeloma cell growth.Crosstalk between microRNA30a/b/c/d/e-5p and the canonical Wnt pathway: implications for multiple myeloma therapy In vivo activity of miR-34a mimics delivered by stable nucleic acid lipid particles (SNALPs) against multiple myeloma Aloperine executes antitumor effects against multiple myeloma through dual apoptotic mechanisms.Expression profile analysis of microRNAs in prostate cancer by next-generation sequencing.Targeting the miR-221-222/PUMA/BAK/BAX Pathway Abrogates Dexamethasone Resistance in Multiple Myeloma.Selective targeting of IRF4 by synthetic microRNA-125b-5p mimics induces anti-multiple myeloma activity in vitro and in vivo.A 13 mer LNA-i-miR-221 Inhibitor Restores Drug Sensitivity in Melphalan-Refractory Multiple Myeloma Cells.Down-regulation of miR-221 inhibits proliferation of pancreatic cancer cells through up-regulation of PTEN, p27(kip1), p57(kip2), and PUMA.Therapeutic strategy with artificially-designed i-lncRNA targeting multiple oncogenic microRNAs exhibits effective antitumor activity in diffuse large B-cell lymphoma.In vitro and in vivo activity of a novel locked nucleic acid (LNA)-inhibitor-miR-221 against multiple myeloma cells.DMET™ (Drug Metabolism Enzymes and Transporters): a pharmacogenomic platform for precision medicine.Potential Value of miR-221/222 as Diagnostic, Prognostic, and Therapeutic Biomarkers for Diseases.MicroRNA-222-3p/GNAI2/AKT axis inhibits epithelial ovarian cancer cell growth and associates with good overall survival.Non-coding RNA: a novel opportunity for the personalized treatment of multiple myeloma.Immunologic microenvironment and personalized treatment in multiple myeloma.Emerging pathways as individualized therapeutic target of multiple myeloma.MicroRNAs as regulators of bone homeostasis and bone metastasis.Mir-34: a new weapon against cancer?miR-30-5p functions as a tumor suppressor and novel therapeutic tool by targeting the oncogenic Wnt/β-catenin/BCL9 pathway.Oncogenic and Therapeutic Targeting of PTEN Loss in Bone Malignancies.miR-29s: a family of epi-miRNAs with therapeutic implications in hematologic malignancies.Inhibition of MicroRNA miR-222 with LNA Inhibitor Can Reduce Cell Proliferation in B Chronic Lymphoblastic Leukemia.The role of circulating miRNAs in multiple myeloma.Mir-221/222 are promising targets for innovative anticancer therapy.MiR-301a promotes cell proliferation by directly targeting TIMP2 in multiple myeloma.Inhibition of miR-21 restores RANKL/OPG ratio in multiple myeloma-derived bone marrow stromal cells and impairs the resorbing activity of mature osteoclasts.

P2860

Q26765477-6B2B4874-0D6E-4B33-AEEE-8DD27D0DCE6E Q26770478-86524C91-9B4C-4FA7-8DF2-F26513AC0BBA Q26824682-D5B88655-5086-4573-A1ED-C1BA7920CA48 Q27005850-6D1CEC2B-6DAE-423A-A90B-8E6FF4EEBB17 Q27014034-3D5578AB-88BD-4A62-AFD9-2BAEE43A9705 Q28074994-4916F1EF-1785-4E20-BB29-9164C5B1D789 Q33786861-E0428845-C9BA-4A39-92D9-7A1B0E80744E Q33889132-FE74933C-8A17-4E36-AB77-8BD900F4EDDF Q33917555-ABB1C80A-5ED8-4993-AD58-A68DFB8FE19F Q33952998-982BC10E-30B6-44C3-B758-D3748D4C3D42 Q33961980-704EEA8B-724C-433B-9DAE-06A46670D709 Q34044638-F8BE6386-2DE3-4E58-9AC8-FC48E9C20764 Q34100915-B45A8A97-7495-4044-8E82-7C269B41742D Q34103347-681FA00F-A53E-4EE6-B108-177980F44E67 Q34287900-FCFCE004-C02D-419F-A15A-22EC7AA784FA Q35108549-6E23399E-9C5A-4E9C-A697-5404AA5CD56F Q35226107-B03C11A9-C76C-41A4-A10E-5E15BDCD7659 Q35544302-D146C1F5-FA73-4F6D-BB9D-AA9CCEF17C44 Q36172671-64029787-AFE2-4470-B408-A6039FBD3ECE Q36254566-F8D7A7E7-EA2F-454B-B57E-4D34C8B8AB29 Q36642951-117FC846-F957-482D-B8A9-60B56BA271CF Q37278413-DE1CF51A-172E-4650-88BF-0684B43131BB Q37580186-355D04E7-2294-458D-966D-FC24B99996C1 Q37597751-A4D0847E-FB49-44CD-9AA8-E3A31302E66E Q37619866-85A4DB17-2519-4910-A338-59F1A3FBFF81 Q37643929-7CED47C3-0C1C-41A3-B803-B57B32DBA477 Q37697052-0BC5FF2A-78A3-4B5A-8154-205CA77662E7 Q38108387-5A83CEB2-2803-4B46-B1F5-F38329723395 Q38108390-27E0B060-7478-4D4C-B851-6E0835CF702A Q38112176-DD986AD1-30CC-462C-AB18-C513260EA6C7 Q38239679-CD3AD689-7DDA-409E-B721-EC226712752B Q38253374-D83FD7B3-300F-4FEA-ACD2-BF3EFC400C5A Q38360083-9B6A6D54-3ED5-4D00-A2E0-82DD4C0EBBEE Q38379348-E5CE7FC6-0D5A-4F0D-BFA5-FCF9DB83630D Q38476564-5A9F4BDE-7F9B-4AB1-8B9F-4AC27E110D0B Q38616907-64092CA8-ABB5-4FCF-AAAE-FEBF0CEA2F90 Q38647786-D50C1A59-707D-4B1B-AAD2-1B6467290202 Q38767024-384D7ED3-99DB-48E8-9627-7314A908DD87 Q38828052-4D99DD9F-23D2-4025-B646-59EE5FA70E3D Q38854653-BAA956DF-7B9D-4734-9670-66B0315A8396

P2860

In vitro and in vivo anti-tumor activity of miR-221/222 inhibitors in multiple myeloma.

http://www.wikidata.org/entity/Q37016562

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on February 2013

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

In vitro and in vivo anti-tumor activity of miR-221/222 inhibitors in multiple myeloma.

@en

In vitro and in vivo anti-tumor activity of miR-221/222 inhibitors in multiple myeloma.

@nl

type

label

In vitro and in vivo anti-tumor activity of miR-221/222 inhibitors in multiple myeloma.

@en

In vitro and in vivo anti-tumor activity of miR-221/222 inhibitors in multiple myeloma.

@nl

prefLabel

In vitro and in vivo anti-tumor activity of miR-221/222 inhibitors in multiple myeloma.

@en

In vitro and in vivo anti-tumor activity of miR-221/222 inhibitors in multiple myeloma.

@nl

P1433

Q37016562-4F717EB7-7E9A-464C-A604-500699BBB57C

P1476

Q37016562-D5CAAB31-3CE5-4420-8992-182CC1F27C7B

P2093

Q37016562-19033A68-E724-415C-9406-A8383E0A83BF

Q37016562-39E20EDF-9E47-4D4C-B3D2-FCA152224F28

Q37016562-3AF6C348-B06C-4325-8527-1100E486DC57

Q37016562-42457988-3EE1-4A94-B93B-EEB51C51807C

Q37016562-430F3FD6-8B50-4F40-B312-4892436D98B2

Q37016562-63ACF0AD-1A64-4B3D-841B-624BBF52DD0D

Q37016562-67E366D4-0F0B-4FC5-964B-0A5A5F9874BE

Q37016562-96A66A68-68FB-429F-A3E9-81C994A4F015

Q37016562-B89B3FC2-46CB-43DE-8520-C21FBDC2BB10

Q37016562-CE0219FA-0CE1-4537-A6E5-302164E856A4

P2860

Q37016562-00B15C35-5B73-44D3-A879-E909026F8F2F

Q37016562-04D6D1A9-7EE2-48C3-8E1B-F6A3B5DB3FF6

Q37016562-05534CB0-92C2-423F-9275-D0E48572C1B3

Q37016562-09762B3D-BCCF-40D3-B959-1877979BD6F7

Q37016562-0E41D25E-018A-4D40-814C-AA58DF8F7214

Q37016562-106A3FEC-0543-4894-884A-B984054EB7C5

Q37016562-10DB4F4C-C76E-4D69-A041-161B55A31B20

Q37016562-259CEA80-FE51-4627-ACE9-9B06765CF119

Q37016562-2719E3A8-49F4-4A3B-B16A-63A1C782DFA1

Q37016562-2C54A0A7-B999-4FFF-B77F-F27995629EED

P304

Q37016562-4F9CE806-C043-46AB-9DE5-456F1D235AF9

P31

Q37016562-36521306-EDA6-4192-9FD8-CA3811C9DFA5

P356

Q37016562-E0BB38F9-1303-4942-8CD1-1EED237D4F36

P407

Q37016562-DBA98CBC-0F6E-4DA4-8315-179C4B897B20

P433

Q37016562-0F6098FD-6F96-4743-B231-187191BF0752

P478

Q37016562-B01E919E-6A2A-42D3-95DC-82A96A5077AE

P50

Q37016562-259EFE75-2F91-47C2-AA57-9AE15627302D

P577

Q37016562-42AA67F2-E11A-42BD-9DB5-26F1FB2E4341

P5875

Q37016562-337C9962-7566-4B18-A6CB-D37C1D117156

P698

Q37016562-33A555CF-714B-48A5-A1EC-A9D3B562B015

P932

Q37016562-5FA627DF-39FF-4B49-A298-7398679FE7FF

P356

P1433

P1476

In vitro and in vivo anti-tumor activity of miR-221/222 inhibitors in multiple myeloma.

@en

P2093

Annamaria Gullà

http://www.w3.org/2001/XMLSchema#string

Antonino Neri

http://www.w3.org/2001/XMLSchema#string

Emanuela Leone

http://www.w3.org/2001/XMLSchema#string

Francesco Conforti

http://www.w3.org/2001/XMLSchema#string

Maria Eugenia Gallo Cantafio

http://www.w3.org/2001/XMLSchema#string

Maria Teresa Di Martino

http://www.w3.org/2001/XMLSchema#string

Mario Cannataro

http://www.w3.org/2001/XMLSchema#string

Marta Lionetti

http://www.w3.org/2001/XMLSchema#string

Nicola Amodio

http://www.w3.org/2001/XMLSchema#string

Pierfrancesco Tassone

http://www.w3.org/2001/XMLSchema#string

P2860

MicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN

Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

miR-221 overexpression contributes to liver tumorigenesis

MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1

Most mammalian mRNAs are conserved targets of microRNAs

miR-221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation

Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

The functions of animal microRNAs

Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection

P304

242-255

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.18632/ONCOTARGET.820

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

4

http://www.w3.org/2001/XMLSchema#string

P50

Antonio Giordano

P577

2013-02-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

235906358

http://www.w3.org/2001/XMLSchema#string

P698

23479461

http://www.w3.org/2001/XMLSchema#string

P932

3712570

http://www.w3.org/2001/XMLSchema#string