Potential role of purinergic signaling in urinary concentration in inner medulla: insights from P2Y2 receptor gene knockout mice
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Purinergic signalling in the kidney in health and diseasePotential role of purinergic signaling in lithium-induced nephrogenic diabetes insipidusThe P2Y2 receptor sensitizes mouse bladder sensory neurons and facilitates purinergic currents.Potential involvement of P2Y2 receptor in diuresis of postobstructive uropathy in rats.Renal sodium transporter/channel expression and sodium excretion in P2Y2 receptor knockout mice fed a high-NaCl diet with/without aldosterone infusionPurinergic activation of Ca2+-permeable TRPV4 channels is essential for mechano-sensitivity in the aldosterone-sensitive distal nephron.Basal release of ATP: an autocrine-paracrine mechanism for cell regulation.Urea transport in the kidney.Genetic analysis of mouse strains with variable serum sodium concentrations identifies the Nalcn sodium channel as a novel player in osmoregulationDeciphering physiological role of the mechanosensitive TRPV4 channel in the distal nephron.Absence of PKC-alpha attenuates lithium-induced nephrogenic diabetes insipidus.Regulation of renal NaCl and water transport by the ATP/UTP/P2Y2 receptor systemTargeting renal purinergic signalling for the treatment of lithium-induced nephrogenic diabetes insipidus.Impaired natriuretic response to high-NaCl diet plus aldosterone infusion in mice overexpressing human CD39, an ectonucleotidase (NTPDase1).Vasopressin and disruption of calcium signalling in polycystic kidney disease.Attenuation of lithium-induced natriuresis and kaliuresis in P2Y₂ receptor knockout miceDefective renal water handling in transgenic mice over-expressing human CD39/NTPDase1Clopidogrel attenuates lithium-induced alterations in renal water and sodium channels/transporters in mice.P2Y12 Receptor Localizes in the Renal Collecting Duct and Its Blockade Augments Arginine Vasopressin Action and Alleviates Nephrogenic Diabetes Insipidus.P2Y receptors and kidney function.Novel insights into TRPV4 function in the kidney.Functional roles of connexins and pannexins in the kidney.Prasugrel suppresses development of lithium-induced nephrogenic diabetes insipidus in mice.AVP-stimulated nucleotide secretion in perfused mouse medullary thick ascending limb and cortical collecting duct.Genetic deletion of the P2Y2 receptor offers significant resistance to development of lithium-induced polyuria accompanied by alterations in PGE2 signaling.
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Potential role of purinergic signaling in urinary concentration in inner medulla: insights from P2Y2 receptor gene knockout mice
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on October 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Potential role of purinergic s ...... Y2 receptor gene knockout mice
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Potential role of purinergic s ...... 2 receptor gene knockout mice.
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type
label
Potential role of purinergic s ...... Y2 receptor gene knockout mice
@en
Potential role of purinergic s ...... 2 receptor gene knockout mice.
@nl
prefLabel
Potential role of purinergic s ...... Y2 receptor gene knockout mice
@en
Potential role of purinergic s ...... 2 receptor gene knockout mice.
@nl
P2093
P2860
P1476
Potential role of purinergic s ...... Y2 receptor gene knockout mice
@en
P2093
Christopher F Martin
Craig D Kamerath
Donald E Kohan
Janet D Klein
Jeff M Sands
Noel G Carlson
Raoul D Nelson
Yuqiang Ge
P2860
P304
P356
10.1152/AJPRENAL.90311.2008
P577
2008-10-01T00:00:00Z