Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis. - Wikidata - wikimedia - TriplyDB

Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis.

Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis.

http://www.wikidata.org/entity/Q37019194

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Multiple Roles of the Small GTPase Rab7 Autophagy, cell death, and cancer Genetics and biology of pancreatic ductal adenocarcinoma Pancreatic Cancer Metabolism: Breaking It Down to Build It Back Up Targeting autophagy in cancer management - strategies and developments Oncogenes strike a balance between cellular growth and homeostasis Amino acid management in cancer Development of autophagy inducers in clinical medicine Chloroquine and hydroxychloroquine for cancer therapy Autophagy in cellular metabolism and cancer Autophagy in cancer Autophagy in malignant transformation and cancer progression Emerging strategies to effectively target autophagy in cancer Autophagy-mediated tumor promotion Targeting mitochondrial metabolism by inhibiting autophagy in BRAF-driven cancers Trial watch: Dendritic cell-based anticancer therapy p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming Therapeutic Targeting of Autophagy Interplay between ROS and autophagy in cancer cells, from tumor initiation to cancer therapy Metabolic pathways promoting cancer cell survival and growth A Novel Small-Molecule Inhibitor Targeting CREB-CBP Complex Possesses Anti-Cancer Effects along with Cell Cycle Regulation, Autophagy Suppression and Endoplasmic Reticulum Stress Autophagy Promotes Focal Adhesion Disassembly and Cell Motility of Metastatic Tumor Cells through the Direct Interaction of Paxillin with LC3 Targeting pathways downstream of KRAS in lung adenocarcinoma.Autophagy and cancer therapy.ATG7 Overexpression Is Crucial for Tumorigenic Growth of Bladder Cancer In Vitro and In Vivo by Targeting the ETS2/miRNA196b/FOXO1/p27 Axis.The Concerted Action of Mitochondrial Dynamics and Positioning: New Characters in Cancer Onset and Progression.The complex landscape of pancreatic cancer metabolism Development of potent autophagy inhibitors that sensitize oncogenic BRAF V600E mutant melanoma tumor cells to vemurafenib Autophagy, Metabolism, and Cancer Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations.Autophagy is required for glucose homeostasis and lung tumor maintenance.Targeting autophagy in breast cancer.Regulation of autophagy and chloroquine sensitivity by oncogenic RAS in vitro is context-dependent.Phase I trial of hydroxychloroquine with dose-intense temozolomide in patients with advanced solid tumors and melanoma A curated census of autophagy-modulating proteins and small molecules: candidate targets for cancer therapy.Risk factors for pancreatic cancer: underlying mechanisms and potential targets.Deregulation of serum microRNA expression is associated with cigarette smoking and lung cancer.Autophagy is essential for effector CD8(+) T cell survival and memory formation.The induction of the p53 tumor suppressor protein bridges the apoptotic and autophagic signaling pathways to regulate cell death in prostate cancer cells.Molecular pathways: autophagy in cancer--a matter of timing and context.

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Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis.

http://www.wikidata.org/entity/Q37019194

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on July 2013

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Autophagy suppresses progressi ...... d maintains lipid homeostasis.

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Autophagy suppresses progressi ...... d maintains lipid homeostasis.

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type

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Autophagy suppresses progressi ...... d maintains lipid homeostasis.

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Autophagy suppresses progressi ...... d maintains lipid homeostasis.

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Autophagy suppresses progressi ...... d maintains lipid homeostasis.

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Autophagy suppresses progressi ...... d maintains lipid homeostasis.

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Genes & Development

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Autophagy suppresses progressi ...... d maintains lipid homeostasis.

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Anne M Strohecker

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Eric Snyder

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Gizem Karsli-Uzunbas

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Guanghua Chen

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Jessie Yanxiang Guo

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Joshua D Rabinowitz

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Robert S Dipaola

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Robin Mathew

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Sandy Price

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Seena C Aisner

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P2860

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

Autophagy suppresses tumorigenesis through elimination of p62

Starvation induced cell death in autophagy-defective yeast mutants is caused by mitochondria dysfunction

Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer

Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae.

p62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

The role of autophagy during the early neonatal starvation period

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

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1447-1461

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10.1101/GAD.219642.113

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13

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27

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Jurre J Kamphorst

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2013-07-01T00:00:00Z

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245028670

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23824538

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3713426

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