Cell cycle- and ribonucleotide reductase-driven changes in mtDNA copy number influence mtDNA Inheritance without compromising mitochondrial gene expression.
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Ancient mtDNA genetic variants modulate mtDNA transcription and replicationMitochondrial genomic variation associated with higher mitochondrial copy number: the Cache County Study on Memory Health and AgingMitochondrial genome instability and ROS enhance intestinal tumorigenesis in APC(Min/+) miceSilencing of PINK1 expression affects mitochondrial DNA and oxidative phosphorylation in dopaminergic cells.Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density.mip1 containing mutations associated with mitochondrial disease causes mutagenesis and depletion of mtDNA in Saccharomyces cerevisiaeRepression of mitochondrial translation, respiration and a metabolic cycle-regulated gene, SLF1, by the yeast Pumilio-family protein Puf3pOverexpression of DNA polymerase zeta reduces the mitochondrial mutability caused by pathological mutations in DNA polymerase gamma in yeast.Possible formation of mitochondrial-RNA containing chimeric or trimeric RNA implies a post-transcriptional and post-splicing mechanism for RNA fusionYeast as a system for modeling mitochondrial disease mechanisms and discovering therapies.Rad53 is essential for a mitochondrial DNA inheritance checkpoint regulating G1 to S progression.MEK2 regulates ribonucleotide reductase activity through functional interaction with ribonucleotide reductase small subunit p53R2.Expression and maintenance of mitochondrial DNA: new insights into human disease pathologyLoss of p53 causes mitochondrial DNA depletion and altered mitochondrial reactive oxygen species homeostasis.Inheritance of the fittest mitochondria in yeast.Crosstalk between mitochondrial stress signals regulates yeast chronological lifespan.Bacterial Signaling Nucleotides Inhibit Yeast Cell Growth by Impacting Mitochondrial and Other Specifically Eukaryotic Functions.Regulation of Small Mitochondrial DNA Replicative Advantage by Ribonucleotide Reductase in Saccharomyces cerevisiae.Potential roles for interactions between the mitochondrial and nuclear DNA throughout the cell cycle of Schizosaccharomyces pombeConvergence of multiple signaling pathways is required to coordinately up-regulate mtDNA and mitochondrial biogenesis during T cell activation.Combined use of Saccharomyces cerevisiae, Caenorhabditis elegans and patient fibroblasts leads to the identification of clofilium tosylate as a potential therapeutic chemical against POLG-related diseases.
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P2860
Cell cycle- and ribonucleotide reductase-driven changes in mtDNA copy number influence mtDNA Inheritance without compromising mitochondrial gene expression.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 07 June 2007
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Cell cycle- and ribonucleotide ...... mitochondrial gene expression.
@en
Cell cycle- and ribonucleotide ...... mitochondrial gene expression.
@nl
type
label
Cell cycle- and ribonucleotide ...... mitochondrial gene expression.
@en
Cell cycle- and ribonucleotide ...... mitochondrial gene expression.
@nl
prefLabel
Cell cycle- and ribonucleotide ...... mitochondrial gene expression.
@en
Cell cycle- and ribonucleotide ...... mitochondrial gene expression.
@nl
P2860
P356
P1433
P1476
Cell cycle- and ribonucleotide ...... mitochondrial gene expression.
@en
P2093
Gerald S Shadel
Maria A Lebedeva
P2860
P304
P356
10.4161/CC.6.16.4572
P577
2007-06-07T00:00:00Z