Sirolimus reduces the incidence and progression of UVB-induced skin cancer in SKH mice even with co-administration of cyclosporine A.
about
Low dose rapamycin exacerbates autoimmune experimental uveitisElevated cutaneous Smad activation associates with enhanced skin tumor susceptibility in organ transplant recipients.Immunosuppressive cyclosporin A activates AKT in keratinocytes through PTEN suppression: implications in skin carcinogenesis.Tomatoes protect against development of UV-induced keratinocyte carcinoma via metabolomic alterations.A preliminary study of the safety of red light phototherapy of tissues harboring cancer.Ultraviolet light exposure stimulates HMGB1 release by keratinocytesPathogenesis of nonmelanoma skin cancers in organ transplant recipientsRapamycin and mTORC1 inhibition in the mouse: skin cancer prevention.Inhibition of mTOR suppresses UVB-induced keratinocyte proliferation and survival.Inhibition of Akt Enhances the Chemopreventive Effects of Topical Rapamycin in Mouse Skin.Cyclosporine A immunosuppression drives catastrophic squamous cell carcinoma through IL-22.Chromosomal aberrations in UVB-induced tumors of immunosuppressed mice.Celecoxib reduces the effects of acute and chronic UVB exposure in mice treated with therapeutically relevant immunosuppressive drugs.Critical review of preclinical approaches to evaluate the potential of immunosuppressive drugs to influence human neoplasia.Synergism between mTOR pathway and ultraviolet radiation in the pathogenesis of squamous cell carcinoma and its implication for solid-organ transplant recipients.Phosphoinositide 3-Kinase-Dependent Signalling Pathways in Cutaneous Squamous Cell Carcinomas.A Topical Zinc Ionophore Blocks Tumorigenic Progression in UV-exposed SKH-1 High-risk Mouse Skin.The mTOR inhibitor rapamycin opposes carcinogenic changes to epidermal Akt1/PKBα isoform signaling.Cyclosporin A, but not everolimus, inhibits DNA repair mediated by calcineurin: implications for tumorigenesis under immunosuppression.Exploiting the origins of Ras mediated squamous cell carcinoma to develop novel therapeutic interventions.Toll-like receptors: role in dermatological disease.While reinforcing cell cycle arrest, rapamycin and Torins suppress senescence in UVA-irradiated fibroblasts.Clinically-Relevant Rapamycin Treatment Regimens Enhance CD8+ Effector Memory T Cell Function In The Skin and Allow their Infiltration into Cutaneous Squamous Cell Carcinoma
P2860
Q28730115-46D39F9C-FDD5-47A4-8234-D5F19BC3EC69Q33614767-CBB62491-FE31-4525-8127-AC0D0A275027Q33799731-2821A578-9453-40A2-94AE-9700AD26C28AQ33895208-EF3D6993-CA70-43CB-B356-20F7281ED938Q34361681-835CB8A3-0E13-4A6C-9E1C-EB53DBFB2A13Q34655362-8FCBC2BB-B117-4D27-8D95-EB92A2ACF638Q34713840-D6D907C4-1973-411A-BD53-A33D303926BAQ35106935-89F27BBE-634A-4B39-8216-099BAFDF5787Q36456697-241DA593-42D4-4C62-A6D1-DEFFAA2DCA9AQ36649878-3EAF899B-B720-4FD0-AC0B-A251EC07A456Q37277272-9A0B07E3-B520-4656-B218-36A27EC5E0F0Q37337088-7E445960-7AB0-4968-B7FF-4C025ADF17E3Q37440010-65A66E66-80E3-4E16-ADBF-727DC149D5D6Q37795414-894AD591-7377-4A0F-9141-CFB4B1A754A8Q38187197-D6555DC3-5B1D-4EE2-BEC8-4C1DFAC7AAB0Q38684394-C14F0309-DC7D-48B4-8F56-07E6D254F78BQ38786525-FC87D8BE-8EEC-4DC8-8E04-EFE060F8A827Q39297991-0FCBA1AB-62C2-4921-B44B-01B14DF94995Q39591754-823A59B2-D6EF-4514-8F14-1174CBE466DCQ39623358-70C90897-97FF-439B-B453-EE68038C0B46Q42431181-8B3EC4E1-98B4-4451-99CF-614378C79456Q49713212-F148F007-7792-49E4-AAA3-F376423911E0Q58037249-7425486B-ECA8-43FF-ADE6-73C32A8121AE
P2860
Sirolimus reduces the incidence and progression of UVB-induced skin cancer in SKH mice even with co-administration of cyclosporine A.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 08 May 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Sirolimus reduces the incidenc ...... inistration of cyclosporine A.
@en
Sirolimus reduces the incidenc ...... inistration of cyclosporine A.
@nl
type
label
Sirolimus reduces the incidenc ...... inistration of cyclosporine A.
@en
Sirolimus reduces the incidenc ...... inistration of cyclosporine A.
@nl
prefLabel
Sirolimus reduces the incidenc ...... inistration of cyclosporine A.
@en
Sirolimus reduces the incidenc ...... inistration of cyclosporine A.
@nl
P2093
P2860
P356
P1476
Sirolimus reduces the incidenc ...... inistration of cyclosporine A.
@en
P2093
Anne M VanBuskirk
Brian C Wulff
Donna F Kusewitt
F Jason Duncan
Jennifer M Thomas-Ahner
Tatiana M Oberyszyn
P2860
P2888
P304
P356
10.1038/JID.2008.121
P407
P577
2008-05-08T00:00:00Z
P5875
P6179
1052538654