Factor XII promotes blood coagulation independent of factor XI in the presence of long-chain polyphosphates.
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In microfluidico: Recreating in vivo hemodynamics using miniaturized devicesPositive selection during the evolution of the blood coagulation factors in the context of their disease-causing mutations.Activated factor XI increases the procoagulant activity of the extrinsic pathway by inactivating tissue factor pathway inhibitorFXIa and platelet polyphosphate as therapeutic targets during human blood clotting on collagen/tissue factor surfaces under flowPlatelet-Derived Short-Chain Polyphosphates Enhance the Inactivation of Tissue Factor Pathway Inhibitor by Activated Coagulation Factor XI.Neutralizing blood-borne polyphosphate in vivo provides safe thromboprotection.Platelets do not express the oxidized or reduced forms of tissue factor.Evidence for factor IX-independent roles for factor XIa in blood coagulation.Factor XII inhibition reduces thrombus formation in a primate thrombosis model.Factor XII: a novel target for safe prevention of thrombosis and inflammation.The contact activation and kallikrein/kinin systems: pathophysiologic and physiologic activities.The hemostatic role of factor XI.Complement, Kinins, and Hereditary Angioedema: Mechanisms of Plasma Instability when C1 Inhibitor is Absent.Differential Roles for the Coagulation Factors XI and XII in Regulating the Physical Biology of Fibrin.Utility of microfluidic devices to study the platelet-endothelium interface.Localization of Short-Chain Polyphosphate Enhances its Ability to Clot Flowing Blood Plasma.Biorheology of platelet activation in the bloodstream distal to thrombus formation.Polyphosphate nanoparticles on the platelet surface trigger contact system activation.Removal of the C-Terminal Domains of ADAMTS13 by Activated Coagulation Factor XI induces Platelet Adhesion on Endothelial Cells under Flow Conditions.
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P2860
Factor XII promotes blood coagulation independent of factor XI in the presence of long-chain polyphosphates.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on July 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Factor XII promotes blood coag ...... of long-chain polyphosphates.
@en
Factor XII promotes blood coag ...... of long-chain polyphosphates.
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type
label
Factor XII promotes blood coag ...... of long-chain polyphosphates.
@en
Factor XII promotes blood coag ...... of long-chain polyphosphates.
@nl
prefLabel
Factor XII promotes blood coag ...... of long-chain polyphosphates.
@en
Factor XII promotes blood coag ...... of long-chain polyphosphates.
@nl
P2093
P2860
P50
P356
P1476
Factor XII promotes blood coag ...... e of long-chain polyphosphates
@en
P2093
P2860
P304
P356
10.1111/JTH.12295
P577
2013-07-01T00:00:00Z