Hoxb7 inhibits transgenic HER-2/neu-induced mouse mammary tumor onset but promotes progression and lung metastasis. - Wikidata - wikimedia - TriplyDB

Hoxb7 inhibits transgenic HER-2/neu-induced mouse mammary tumor onset but promotes progression and lung metastasis.

Hoxb7 inhibits transgenic HER-2/neu-induced mouse mammary tumor onset but promotes progression and lung metastasis.

http://www.wikidata.org/entity/Q37023738

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The HOXB7 protein renders breast cancer cells resistant to tamoxifen through activation of the EGFR pathway.HOXB7 accelerates the malignant progression of hepatocellular carcinoma by promoting stemness and epithelial-mesenchymal transition Somatic expression of PyMT or activated ErbB2 induces estrogen-independent mammary tumorigenesis.Proteomic characterization of Her2/neu-overexpressing breast cancer cells.HOXB7 promotes malignant progression by activating the TGFβ signaling pathway.Continuous requirement of ErbB2 kinase activity for loss of cell polarity and lumen formation in a novel ErbB2/Neu-driven murine cell line model of metastatic breast cancer.Deregulated HOXB7 Expression Predicts Poor Prognosis of Patients with Esophageal Squamous Cell Carcinoma and Regulates Cancer Cell Proliferation In Vitro and In Vivo.HOXB7 Is an ERα Cofactor in the Activation of HER2 and Multiple ER Target Genes Leading to Endocrine Resistance.HOXB7-S3 inhibits the proliferation and invasion of MCF-7 human breast cancer cells.Overexpression of HOXB7 is associated with a poor prognosis in patients with gastric cancer Identification of several potential chromatin binding sites of HOXB7 and its downstream target genes in breast cancer.HOXB7 as a promising molecular marker for metastasis in cancers: a meta-analysis.The Widening Sphere of Influence of HOXB7 in Solid Tumors A novel double-negative feedback loop between miR-489 and the HER2-SHP2-MAPK signaling axis regulates breast cancer cell proliferation and tumor growth Tumor suppressor p16INK4A is necessary for survival of cervical carcinoma cell lines.HOXB7 promotes invasion and predicts survival in pancreatic adenocarcinoma.HOXB7 overexpression promotes cell proliferation and correlates with poor prognosis in gastric cancer patients by inducing expression of both AKT and MARKs.Levels of HOXB7 and miR-337 in pancreatic ductal adenocarcinoma patients.The molecular and cellular heterogeneity of pancreatic ductal adenocarcinoma.Analysis of regulatory networks constructed based on gene coexpression in pituitary adenoma.miR-337 regulates the proliferation and invasion in pancreatic ductal adenocarcinoma by targeting HOXB7.Overexpression of HOXB7 protein reduces sensitivity of oral cancer cells to chemo-radiotherapy.Targeting the HOX/PBX dimer in breast cancer.Role of HOXB7 in regulation of progression and metastasis of human lung adenocarcinoma.HOXB7 expression by myeloma cells regulates their pro-angiogenic properties in multiple myeloma patients.Increased copy number of the DLX4 homeobox gene in breast axillary lymph node metastasis.Immunoexpression of hoxb7 and hoxb9 in salivary gland tumours.Prognostic value of HOXB7 mRNA expression in human oesophageal squamous cell cancer.The transcription factor HOXB7 regulates ERK kinase activity and thereby stimulates the motility and invasiveness of pancreatic cancer cells.HOXC8 promotes proliferation and migration through transcriptional up-regulation of TGFβ1 in non-small cell lung cancer.The roles of HOXB7 in promoting migration, invasion, and anti-apoptosis in gastric cancer.Upregulation of HOXB7 promotes the tumorigenesis and progression of gastric cancer and correlates with clinical characteristics.Proteomic profiling of cancer stem cells derived from primary tumors of HER2/Neu transgenic mice.Hoxa5: A Key Player in Development and Disease.Expressional analysis of disease-relevant signalling-pathways in primary tumours and metastasis of head and neck cancers.

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Hoxb7 inhibits transgenic HER-2/neu-induced mouse mammary tumor onset but promotes progression and lung metastasis.

http://www.wikidata.org/entity/Q37023738

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 07 May 2008

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

@cs

name

Hoxb7 inhibits transgenic HER- ...... ogression and lung metastasis.

@en

Hoxb7 inhibits transgenic HER- ...... ogression and lung metastasis.

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type

label

Hoxb7 inhibits transgenic HER- ...... ogression and lung metastasis.

@en

Hoxb7 inhibits transgenic HER- ...... ogression and lung metastasis.

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prefLabel

Hoxb7 inhibits transgenic HER- ...... ogression and lung metastasis.

@en

Hoxb7 inhibits transgenic HER- ...... ogression and lung metastasis.

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0008-5472.CAN-07-2926

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Cancer Research

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Hoxb7 inhibits transgenic HER- ...... ogression and lung metastasis.

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Alan Rein

http://www.w3.org/2001/XMLSchema#string

Cynthia Zahnow

http://www.w3.org/2001/XMLSchema#string

Hexin Chen

http://www.w3.org/2001/XMLSchema#string

Huiping Zhang

http://www.w3.org/2001/XMLSchema#string

Ji Shin Lee

http://www.w3.org/2001/XMLSchema#string

Lionel Feigenbaum

http://www.w3.org/2001/XMLSchema#string

M Evangeline Taylor

http://www.w3.org/2001/XMLSchema#string

Saraswati Sukumar

http://www.w3.org/2001/XMLSchema#string

Tao Zhu

http://www.w3.org/2001/XMLSchema#string

Xiaohui Liang

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P2860

Expression of multiple homeobox genes within diverse mammalian haemopoietic lineages

HOXB7 constitutively activates basic fibroblast growth factor in melanomas

Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis

Loss of the tight junction protein claudin-7 correlates with histological grade in both ductal carcinoma in situ and invasive ductal carcinoma of the breast

Identification of transcriptional targets of HOXA5

Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up

Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease.

Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer

Hox genes in vertebrate development

Homeobox genes and cancer.

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3637-3644

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scholarly article

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10.1158/0008-5472.CAN-07-2926

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10

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2008-05-07T00:00:00Z

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5389051

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18463397

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3715065

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