The fractalkine/CX3CR1 system regulates β cell function and insulin secretion
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Insulin-secreting β cells require a post-genomic conceptMetabolic Effects of CX3CR1 Deficiency in Diet-Induced Obese MiceIncreased adipocyte O2 consumption triggers HIF-1α, causing inflammation and insulin resistance in obesity.Fractalkine (CX3CL1), a new factor protecting β-cells against TNFαMacrophage recruitment in obese adipose tissuePancreatic stellate cells and CX3CR1: occurrence in normal pancreas and acute and chronic pancreatitis and effect of their activation by a CX3CR1 agonistNutritional energy stimulates NAD+ production to promote tankyrase-mediated PARsylation in insulinoma cellsGPR43 Potentiates β-Cell Function in Obesity.CX3CR1 is a gatekeeper for intestinal barrier integrity in mice: Limiting steatohepatitis by maintaining intestinal homeostasis.Chemokine receptors CXCR2 and CX3CR1 differentially regulate functional responses of bone-marrow endothelial progenitors during atherosclerotic plaque regressionSerum Fractalkine (CX3CL1) and Cardiovascular Outcomes and Diabetes: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study.Fractalkine signaling in regulation of insulin secretion.Modeling the Role of Lanthionine Synthetase C-Like 2 (LANCL2) in the Modulation of Immune Responses to Helicobacter pylori Infection.Assessment of the Role of Metabolic Determinants on the Relationship between Insulin Sensitivity and Secretion.Exclusive CX3CR1 dependence of kidney DCs impacts glomerulonephritis progressionPancreatic stellate cell: Pandora's box for pancreatic disease biology.Sex differences in microglial CX3CR1 signalling determine obesity susceptibility in mice.Roles of the chemokine system in development of obesity, insulin resistance, and cardiovascular disease.An excessive increase in glutamate contributes to glucose-toxicity in β-cells via activation of pancreatic NMDA receptors in rodent diabetes.Myokines in insulin resistance and type 2 diabetes.A role for maternally derived myokines to optimize placental function and fetal growth across gestation.Role of CX3CL1 in Diseases.FFAR3 modulates insulin secretion and global gene expression in mouse islets.Glia: silent partners in energy homeostasis and obesity pathogenesis.A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice.Pancreatic islet inflammation: an emerging role for chemokines.Differences in metabolic biomarkers in the blood and gene expression profiles of peripheral blood mononuclear cells among normal weight, mildly obese and moderately obese subjects.Ion channel TRPV1-dependent activation of PTP1B suppresses EGFR-associated intestinal tumorigenesis.ERV1 Overexpression in Myeloid Cells Protects against High Fat Diet Induced Obesity and Glucose Intolerance.Chromogranin A regulates vesicle storage and mitochondrial dynamics to influence insulin secretion.Essential involvement of the CX3CL1-CX3CR1 axis in bleomycin-induced pulmonary fibrosis via regulation of fibrocyte and M2 macrophage migration.Synergistic Modulation of Inflammatory but not Metabolic Effects of High-Fat Feeding by CCR2 and CX3CR1.Inhibition of Miro1 disturbs mitophagy and pancreatic β-cell function interfering insulin release via IRS-Akt-Foxo1 in diabetes.Modulation of Gr1low monocyte subset impacts insulin sensitivity and weight gain upon high-fat diet in female mice.Hepatitis B X-interacting protein promotes the formation of the insulin gene-transcribing protein complex Pdx-1/NeuroD1 in animal pancreatic β cells.Oncogenic RAS-induced downregulation of ATG12 is required for survival of malignant intestinal epithelial cells.Chronic fractalkine administration improves glucose tolerance and pancreatic endocrine function.
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P2860
The fractalkine/CX3CR1 system regulates β cell function and insulin secretion
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 2013
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The fractalkine/CX3CR1 system regulates β cell function and insulin secretion
@en
The fractalkine/CX3CR1 system regulates β cell function and insulin secretion.
@nl
type
label
The fractalkine/CX3CR1 system regulates β cell function and insulin secretion
@en
The fractalkine/CX3CR1 system regulates β cell function and insulin secretion.
@nl
prefLabel
The fractalkine/CX3CR1 system regulates β cell function and insulin secretion
@en
The fractalkine/CX3CR1 system regulates β cell function and insulin secretion.
@nl
P2093
P2860
P1433
P1476
The fractalkine/CX3CR1 system regulates β cell function and insulin secretion
@en
P2093
Ayse G Kayali
Guy Perkins
Hidetaka Morinaga
Ian R Sweet
Jane J Kim
Malik Keshwani
Susan Taylor
William Lagakos
Yun Sok Lee
P2860
P304
P356
10.1016/J.CELL.2013.03.001
P407
P577
2013-04-01T00:00:00Z