Mechanistic role of calpains in postischemic neurodegeneration.
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Adaptive preconditioning in neurological diseases – therapeutic insights from proteostatic perturbationsHsp70.1 and related lysosomal factors for necrotic neuronal deathCalpains mediate epithelial-cell death during mammary gland involution: mitochondria and lysosomal destabilizationCalpain-cleaved type 1 inositol 1,4,5-trisphosphate receptor (InsP(3)R1) has InsP(3)-independent gating and disrupts intracellular Ca(2+) homeostasisInvolvement of calpains in adult neurogenesis: implications for stroke.Reperfusion-induced temporary appearance of therapeutic window in penumbra after 2 h of photothrombotic middle cerebral artery occlusion in rats.Role of the proteasome in excitotoxicity-induced cleavage of glutamic acid decarboxylase in cultured hippocampal neurons.Calpain mediates proteolysis of the voltage-gated sodium channel alpha-subunit.Disruption of the axon initial segment cytoskeleton is a new mechanism for neuronal injury.Calcium-activated calpain-2 is a mediator of beta cell dysfunction and apoptosis in type 2 diabetes.Axonal Membranes and Their Domains: Assembly and Function of the Axon Initial Segment and Node of Ranvier.Neuroprotection with delayed calpain inhibition after transient forebrain ischemia.RNAi targeting micro-calpain increases neuron survival and preserves hippocampal function after global brain ischemia.Conditional disruption of calpain in the CNS alters dendrite morphology, impairs LTP, and promotes neuronal survival following injury.Neuronal necrosis is regulated by a conserved chromatin-modifying cascade.Death and consciousness--an overview of the mental and cognitive experience of death.Prion pathogenesis is faithfully reproduced in cerebellar organotypic slice cultures.Free fatty acid induces endoplasmic reticulum stress and apoptosis of β-cells by Ca2+/calpain-2 pathways.Mechanism of action of thalassospiramides, a new class of calpain inhibitorsIn vitro ischemia triggers a transcriptional response to down-regulate synaptic proteins in hippocampal neurons.Calpain inhibition attenuates angiotensin II-induced abdominal aortic aneurysms and atherosclerosis in low-density lipoprotein receptor-deficient mice.Gephyrin Cleavage in In Vitro Brain Ischemia Decreases GABAA Receptor Clustering and Contributes to Neuronal Death.Chronic intermittent ethanol induced axon and myelin degeneration is attenuated by calpain inhibition.Brain ischemia downregulates the neuroprotective GDNF-Ret signaling by a calpain-dependent mechanism in cultured hippocampal neurons.Calcium-dependent mitochondrial function and dysfunction in neurons.Targeting the nNOS/peroxynitrite/calpain system to confer neuroprotection and aid functional recovery in a mouse model of TBI.Glutamate transporters in brain ischemia: to modulate or not?Activation of asparaginyl endopeptidase leads to Tau hyperphosphorylation in Alzheimer disease.Mechanisms of calpain mediated proteolysis of voltage gated sodium channel α-subunits following in vitro dynamic stretch injuryKnockdown of m-calpain increases survival of primary hippocampal neurons following NMDA excitotoxicity.Calpain-mediated signaling mechanisms in neuronal injury and neurodegenerationPoly(ADP-ribose) signals to mitochondrial AIF: a key event in parthanatos.Role of calpains in the injury-induced dysfunction and degeneration of the mammalian axon.Inhibition of Histone Deacetylase 3 (HDAC3) Mediates Ischemic Preconditioning and Protects Cortical Neurons against Ischemia in RatsCalpain and the glutamatergic synapseCalpain as a therapeutic target in traumatic brain injury.Expression of Nampt in hippocampal and cortical excitatory neurons is critical for cognitive function.Calpain inhibitors: a survey of compounds reported in the patent and scientific literature.Endoplasmic-reticulum calcium depletion and disease.Neuroprotection by GDNF in the ischemic brain.
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Mechanistic role of calpains in postischemic neurodegeneration.
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 12 December 2007
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vedecký článok
@sk
vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Mechanistic role of calpains in postischemic neurodegeneration.
@en
Mechanistic role of calpains in postischemic neurodegeneration.
@nl
type
label
Mechanistic role of calpains in postischemic neurodegeneration.
@en
Mechanistic role of calpains in postischemic neurodegeneration.
@nl
prefLabel
Mechanistic role of calpains in postischemic neurodegeneration.
@en
Mechanistic role of calpains in postischemic neurodegeneration.
@nl
P2860
P356
P1476
Mechanistic role of calpains in postischemic neurodegeneration.
@en
P2093
Matthew B Bevers
Robert W Neumar
P2860
P304
P356
10.1038/SJ.JCBFM.9600595
P577
2007-12-12T00:00:00Z