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Multifaceted oncolytic virus therapy for glioblastoma in an immunocompetent cancer stem cell model.

Multifaceted oncolytic virus therapy for glioblastoma in an immunocompetent cancer stem cell model.

http://www.wikidata.org/entity/Q37031739

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Oncolytic virus therapy: A new era of cancer treatment at dawn To Infection and Beyond: The Multi-Pronged Anti-Cancer Mechanisms of Oncolytic Viruses Oncolytic herpes simplex virus-based strategies: toward a breakthrough in glioblastoma therapy Immunotherapy for primary brain tumors: no longer a matter of privilege Oncolytic viruses as anticancer vaccines Treatment of orthotopic malignant peripheral nerve sheath tumors with oncolytic herpes simplex virus.Identification and characterization of alphavirus M1 as a selective oncolytic virus targeting ZAP-defective human cancers.Choindroitinase ABC I-mediated enhancement of oncolytic virus spread and anti tumor efficacy: a mathematical model.In vitro screen of a small molecule inhibitor drug library identifies multiple compounds that synergize with oncolytic myxoma virus against human brain tumor-initiating cells Designing Herpes Viruses as Oncolytics.Heterogeneity of Cancer Stem Cells: Rationale for Targeting the Stem Cell Niche.Systemic delivery of HER2-retargeted oncolytic-HSV by mesenchymal stromal cells protects from lung and brain metastases.EXPLORING THE ANTITUMOR EFFECT OF VIRUS IN MALIGNANT GLIOMA Single agent efficacy of the VEGFR kinase inhibitor axitinib in preclinical models of glioblastoma Viral therapy of glioblastoma multiforme.Targeting cancer stem cells with oncolytic virus A patient-specific therapeutic approach for tumour cell population extinction and drug toxicity reduction using control systems-based dose-profile design.11R-P53 and GM-CSF Expressing Oncolytic Adenovirus Target Cancer Stem Cells with Enhanced Synergistic Activity.Evolution of oncolytic viruses: novel strategies for cancer treatment.Oncolytic viruses and their application to cancer immunotherapy Oncolytic viral therapy: targeting cancer stem cells Stem cell in alternative treatments for brain tumors: potential for gene delivery.Calpain-dependent clearance of the autophagy protein p62/SQSTM1 is a contributor to ΔPK oncolytic activity in melanoma.In situ vaccination: Cancer immunotherapy both personalized and off-the-shelf.Gene therapy approaches against cancer using in vivo and ex vivo gene transfer of interleukin-12.In situ vaccination for the treatment of cancer.Preclinical Mouse Models for Analysis of the Therapeutic Potential of Engineered Oncolytic Herpes Viruses In vitro screening of clinical drugs identifies sensitizers of oncolytic viral therapy in glioblastoma stem-like cells.Safety and antitumor effect of oncolytic and helper-dependent adenoviruses expressing interleukin-12 variants in a hamster pancreatic cancer model.Oncolytic virus as a cancer stem cell killer: progress and challenges.Oncolytic herpes simplex virus interactions with the host immune system.M011L-deficient oncolytic myxoma virus induces apoptosis in brain tumor-initiating cells and enhances survival in a novel immunocompetent mouse model of glioblastoma Zika virus has oncolytic activity against glioblastoma stem cells.Macrophage Polarization Contributes to Glioblastoma Eradication by Combination Immunovirotherapy and Immune Checkpoint Blockade.Stem cell-released oncolytic herpes simplex virus has therapeutic efficacy in brain metastatic melanomas.Therapeutic targeting of chemoresistant and recurrent glioblastoma stem cells with a proapoptotic variant of oncolytic herpes simplex virus.A new patient-derived orthotopic malignant meningioma model treated with oncolytic herpes simplex virus.Targeting Nucleotide Biosynthesis: A Strategy for Improving the Oncolytic Potential of DNA Viruses.Immunovirotherapy for the treatment of glioblastoma.Stem cells loaded with multimechanistic oncolytic herpes simplex virus variants for brain tumor therapy.

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Multifaceted oncolytic virus therapy for glioblastoma in an immunocompetent cancer stem cell model.

http://www.wikidata.org/entity/Q37031739

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 10 June 2013

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Multifaceted oncolytic virus t ...... petent cancer stem cell model.

@en

Multifaceted oncolytic virus t ...... petent cancer stem cell model.

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type

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Multifaceted oncolytic virus t ...... petent cancer stem cell model.

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Multifaceted oncolytic virus t ...... petent cancer stem cell model.

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Multifaceted oncolytic virus t ...... petent cancer stem cell model.

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PNAS.1307935110

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Proceedings of the National Academy of Sciences of the United States of America

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Multifaceted oncolytic virus t ...... petent cancer stem cell model.

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Deva S Jeyaretna

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Hiroaki Wakimoto

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Jianfang Ning

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Peter E Fecci

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Tooba A Cheema

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P2860

Malignant gliomas in adults

Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

Flip-Flop HSV-BAC: bacterial artificial chromosome based system for rapid generation of recombinant herpes simplex virus vectors using two independent site-specific recombinases.

Enhanced antitumor efficacy of vasculostatin (Vstat120) expressing oncolytic HSV-1.

CXCL10 can inhibit endothelial cell proliferation independently of CXCR3.

Immunobiological characterization of cancer stem cells isolated from glioblastoma patients.

Glioma-associated cancer-initiating cells induce immunosuppression.

Coordination of early protective immunity to viral infection by regulatory T cells

VEGF-targeted therapy: mechanisms of anti-tumour activity.

Glioma cancer stem cells induce immunosuppressive macrophages/microglia.

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12006-12011

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10.1073/PNAS.1307935110

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29

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110

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Toshihiko Kuroda

Samuel D Rabkin

Robert L Martuza

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2013-06-10T00:00:00Z

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23754388

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oncolytic virus

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3718117

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