Modulation of telomere length dynamics by the subtelomeric region of tetrahymena telomeres.
about
Tetrahymena POT1a regulates telomere length and prevents activation of a cell cycle checkpoint.Mesenchymal stem cells with high telomerase expression do not actively restore their chromosome arm specific telomere length pattern after exposure to ionizing radiation.Tetrahymena Pot2 is a developmentally regulated paralog of Pot1 that localizes to chromosome breakage sites but not to telomeres.The Pot1a-associated proteins Tpt1 and Pat1 coordinate telomere protection and length regulation in Tetrahymena.DNA-guided establishment of nucleosome patterns within coding regions of a eukaryotic genome.Simple telomeres in a simple animal: absence of subtelomeric repeat regions in the placozoan Trichoplax adhaerens.The 3' overhangs at Tetrahymena thermophila telomeres are packaged by four proteins, Pot1a, Tpt1, Pat1, and Pat2.Direct single-stranded DNA binding by Teb1 mediates the recruitment of Tetrahymena thermophila telomerase to telomeres.
P2860
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P2860
Modulation of telomere length dynamics by the subtelomeric region of tetrahymena telomeres.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 28 May 2004
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Modulation of telomere length ...... gion of tetrahymena telomeres.
@en
Modulation of telomere length ...... gion of tetrahymena telomeres.
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type
label
Modulation of telomere length ...... gion of tetrahymena telomeres.
@en
Modulation of telomere length ...... gion of tetrahymena telomeres.
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prefLabel
Modulation of telomere length ...... gion of tetrahymena telomeres.
@en
Modulation of telomere length ...... gion of tetrahymena telomeres.
@nl
P2093
P2860
P356
P1476
Modulation of telomere length ...... gion of tetrahymena telomeres.
@en
P2093
Angela R Stout
Carolyn M Price
Naduparambil K Jacob
P2860
P304
P356
10.1091/MBC.E04-03-0237
P577
2004-05-28T00:00:00Z