Production of diglyceride from phosphatidylinositol in activated human platelets.
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Protease-activated receptor 1 is the primary mediator of thrombin-stimulated platelet procoagulant activityThrombin and C-kinase activators potentiate calcium-stimulated arachidonic acid release in human plateletsInositol lipids, phosphatidate and diacylglycerol share stearoylarachidonoylglycerol as a common backbone in thrombin-stimulated human plateletsHow is the level of free arachidonic acid controlled in mammalian cells?Sub-second oscillations of inositol 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate during platelet activation by ADP and thrombin: lack of correlation with calcium kinetics.Stimulus-specific induction of phospholipid and arachidonic acid metabolism in human neutrophils.Receptor-mediated release of endothelium-derived relaxing factor and prostacyclin from bovine aortic endothelial cells is coupled.Ca2+-channel blockers inhibit the action of recombinant platelet-derived growth factor in vascular smooth muscle cellsReceptor-dependent regulation of [Ca2+]i and phospholipase C in vascular endothelial cells.Protease activated receptors: theme and variations.Adenosine triphosphate stimulates inositol phospholipid metabolism and prostacyclin formation in adrenal medullary endothelial cells by means of P2-purinergic receptors.Modulation of human platelet protein kinase C by endotoxic lipid A.Inositol 1,4,5-triphosphate-induced granule secretion in platelets. Evidence that the activation of phospholipase C mediated by platelet thromboxane receptors involves a guanine nucleotide binding protein-dependent mechanism distinct from that of th(-)-Adrenaline-induced, calcium-dependent phosphorylation of proteins in human plateletsRole of calcium and phosphoinositides in the actions of certain hormones and neurotransmittersAnalysis of prostaglandin E2 effect on T lymphocyte activation. Abrogation of prostaglandin E2 inhibitory effect by the tumor promotor 12.0 tetradecanoyl phorbol-13 acetatePlatelet protein phosphorylation, elevation of cytosolic calcium, and inositol phospholipid breakdown in platelet activation induced by plasminSynergism between the contractile effect of epidermal growth factor and that of des-Arg9-bradykinin or of alpha-thrombin in rabbit aortic rings.Biochemical studies on cell fusion. II. Control of fusion response by lipid alteration.Evidence that the Rous sarcoma virus transforming gene product phosphorylates phosphatidylinositol and diacylglycerolRole of Ca2+ and cyclic AMP in the regulation of the production of prostacyclin by the vascular endothelium.Cytochalasins inhibit arachidonic acid metabolism in thrombin-stimulated platelets.Arachidonic acid metabolism in polymorphonuclear leukocytes from patients with chronic granulomatous diseaseEvidence for a role in stimulus--secretion coupling of prostaglandins derived from release of arachidonoyl residues as a result of phosphatidylinositol breakdown.Phosphatidylinositol-specific phospholipase C in fetal membranes and uterine deciduaEffect of fatty acid modification on prostacyclin production by cultured human endothelial cells.Phospholipid metabolism in stimulated human platelets. Changes in phosphatidylinositol, phosphatidic acid, and lysophospholipidsDiglyceride lipase: a pathway for arachidonate release from human platelets.Marked increase of human platelet phospholipase A2 activity in vitro and demonstration of an endogenous inhibitor.Removal of extraplatelet Na+ eliminates indomethacin-sensitive secretion from human platelets stimulated by epinephrine, ADP, and thrombin.Human platelets contain phospholipase C that hydrolyzes polyphosphoinositides.Rapid formation of diacylglycerol from phosphatidylcholine: a pathway for generation of a second messenger.Low density lipoprotein causes general cellular activation with increased phosphatidylinositol turnover and lipoprotein catabolism.Inhibition of human platelet phospholipase A2 activity by unsaturated fatty acidsPlatelet function and Isoprostane biology. Should isoprostanes be the newest member of the orphan-ligand family?Control mechanisms of mediator release in human basophils and mast cells.Gaining access to the cytosol: the technique and some applications of electropermeabilization.Inositol trisphosphate and diacylglycerol as second messengers.What is the function of phospholipid N-methylation?Altered diacylglycerol level and metabolism in neutrophils from patients with localized juvenile periodontitis.
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P2860
Production of diglyceride from phosphatidylinositol in activated human platelets.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 1979
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Production of diglyceride from phosphatidylinositol in activated human platelets.
@en
Production of diglyceride from phosphatidylinositol in activated human platelets.
@nl
type
label
Production of diglyceride from phosphatidylinositol in activated human platelets.
@en
Production of diglyceride from phosphatidylinositol in activated human platelets.
@nl
prefLabel
Production of diglyceride from phosphatidylinositol in activated human platelets.
@en
Production of diglyceride from phosphatidylinositol in activated human platelets.
@nl
P2860
P356
P1476
Production of diglyceride from phosphatidylinositol in activated human platelets.
@en
P2093
Rittenhouse-Simmons S
P2860
P304
P356
10.1172/JCI109339
P407
P577
1979-04-01T00:00:00Z