Voltage-dependent K+ channel gating and voltage sensor toxin sensitivity depend on the mechanical state of the lipid membrane
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Piezo proteins are pore-forming subunits of mechanically activated channels.Interactions between lipids and voltage sensor paddles detected with tarantula toxinsVoltage gated ion channel function: gating, conduction, and the role of water and protonsMechanical properties of lipid bilayers and regulation of mechanosensitive function: from biological to biomimetic channelsMechanosensitive gating of Kv channelsSolution Structure and Phospholipid Interactions of the Isolated Voltage-Sensor Domain from KvAPSpontaneous excitation patterns computed for axons with injury-like impairments of sodium channels and Na/K pumpsCardiac Mechano-Gated Ion Channels and Arrhythmias.Feeling the hidden mechanical forces in lipid bilayer is an original senseβ-Barrel mobility underlies closure of the voltage-dependent anion channelMembrane Electromechanics in Biology, with a Focus on Hearing.Baifuzi reduces transient ischemic brain damage through an interaction with the STREX domain of BKCa channels.Function of Shaker potassium channels produced by cell-free translation upon injection into Xenopus oocytesLipid-protein nanodiscs offer new perspectives for structural and functional studies of water-soluble membrane-active peptidesFunctional reconstitution of a voltage-gated potassium channel in giant unilamellar vesicles.Interaction with phosphoinositides confers adaptation onto the TRPV1 pain receptor.Structure and hydration of membranes embedded with voltage-sensing domains.Regulation of ion channel function by the host lipid bilayer examined by a stopped-flow spectrofluorometric assay.Target promiscuity and heterogeneous effects of tarantula venom peptides affecting Na+ and K+ ion channels.Targeting voltage sensors in sodium channels with spider toxins.Hypericin prolongs action potential duration in hippocampal neurons by acting on K+ channels.Calculation of the gating charge for the Kv1.2 voltage-activated potassium channelStructure and orientation of a voltage-sensor toxin in lipid membranes.A bivalent tarantula toxin activates the capsaicin receptor, TRPV1, by targeting the outer pore domainEffects of GsMTx4 on bacterial mechanosensitive channels in inside-out patches from giant spheroplasts.The tarantula toxins ProTx-II and huwentoxin-IV differentially interact with human Nav1.7 voltage sensors to inhibit channel activation and inactivation.Position and motions of the S4 helix during opening of the Shaker potassium channel.Interaction between soluble and membrane-embedded potassium channel peptides monitored by Fourier transform infrared spectroscopy.Membrane insertion of a voltage sensor helixStructural interactions of a voltage sensor toxin with lipid membranes.Lipid lateral mobility in cochlear outer hair cells: regional differences and regulation by cholesterolLipidomics at the interface of structure and function in systems biologyNavβ subunits modulate the inhibition of Nav1.8 by the analgesic gating modifier μO-conotoxin MrVIBReconstitution of a transmembrane protein, the voltage-gated ion channel, KvAP, into giant unilamellar vesicles for microscopy and patch clamp studiesEmerging roles for lipids in shaping membrane-protein function.Lipid bilayer mechanics in a pipette with glass-bilayer adhesionTarantula toxins use common surfaces for interacting with Kv and ASIC ion channels.The core domain as the force sensor of the yeast mechanosensitive TRP channel.Palmitoylation influences the function and pharmacology of sodium channels.Halothane changes the domain structure of a binary lipid membrane.
P2860
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P2860
Voltage-dependent K+ channel gating and voltage sensor toxin sensitivity depend on the mechanical state of the lipid membrane
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 02 December 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Voltage-dependent K+ channel g ...... al state of the lipid membrane
@en
Voltage-dependent K+ channel g ...... l state of the lipid membrane.
@nl
type
label
Voltage-dependent K+ channel g ...... al state of the lipid membrane
@en
Voltage-dependent K+ channel g ...... l state of the lipid membrane.
@nl
prefLabel
Voltage-dependent K+ channel g ...... al state of the lipid membrane
@en
Voltage-dependent K+ channel g ...... l state of the lipid membrane.
@nl
P2860
P356
P1476
Voltage-dependent K+ channel g ...... al state of the lipid membrane
@en
P2093
Daniel Schmidt
P2860
P304
19276-19281
P356
10.1073/PNAS.0810187105
P407
P577
2008-12-02T00:00:00Z