Dysregulated editing of serotonin 2C receptor mRNAs results in energy dissipation and loss of fat mass
about
A-to-I editing of coding and non-coding RNAs by ADARsRNA-binding proteins, neural development and the addictionsAdenosine-to-inosine RNA editing and human diseaseQuantitative analysis of 5HT(2C) receptor RNA editing patterns in psychiatric disordersFunctions of the RNA Editing Enzyme ADAR1 and Their Relevance to Human DiseasesRapid and dynamic transcriptome regulation by RNA editing and RNA modificationsLoss of the imprinted snoRNA mbii-52 leads to increased 5htr2c pre-RNA editing and altered 5HT2CR-mediated behaviourFunctions and regulation of RNA editing by ADAR deaminasesTranscript diversification in the nervous system: a to I RNA editing in CNS function and disease developmentDeciphering the functions and regulation of brain-enriched A-to-I RNA editingImpact of RNA editing on functions of the serotonin 2C receptor in vivoMolecular diversity through RNA editing: a balancing act.Assessing serotonin receptor mRNA editing frequency by a novel ultra high-throughput sequencing method.High-throughput multiplexed transcript analysis yields enhanced resolution of 5-hydroxytryptamine 2C receptor mRNA editing profiles.Mice with altered serotonin 2C receptor RNA editing display characteristics of Prader-Willi syndrome.Mood, food, and obesity.Functional relevance of serotonin 2C receptor mRNA editing in antidepressant- and anxiety-like behaviors.Potent and selective inhibition of A-to-I RNA editing with 2'-O-methyl/locked nucleic acid-containing antisense oligoribonucleotides.Quantitative analysis of focused a-to-I RNA editing sites by ultra-high-throughput sequencing in psychiatric disorders.Enhancement of alcohol drinking in mice depends on alterations in RNA editing of serotonin 2C receptors.Prevention of 5-hydroxytryptamine2C receptor RNA editing and alternate splicing in C57BL/6 mice activates the hypothalamic-pituitary-adrenal axis and alters moodLeucine deprivation stimulates fat loss via increasing CRH expression in the hypothalamus and activating the sympathetic nervous systemDynamic 5-HT2C receptor editing in a mouse model of obesity.Hyperactive hypothalamus, motivated and non-distractible chronic overeating in ADAR2 transgenic mice.Reduced levels of protein recoding by A-to-I RNA editing in Alzheimer's diseaseDecoding neuroproteomics: integrating the genome, translatome and functional anatomyEditing of serotonin 2C receptor mRNA in the prefrontal cortex characterizes high-novelty locomotor response behavioral trait.Serotonin 2C receptors in pro-opiomelanocortin neurons regulate energy and glucose homeostasis.Meta-analysis identifies gene-by-environment interactions as demonstrated in a study of 4,965 mice.CAPS1 RNA Editing Promotes Dense Core Vesicle ExocytosisRegulation of alternative splicing by short non-coding nuclear RNAs.Genetic factors in exercise adoption, adherence and obesity.Changing blue fluorescent protein to green fluorescent protein using chemical RNA editing as a novel strategy in genetic restoration.Model mice for 15q11-13 duplication syndrome exhibit late-onset obesity and altered lipid metabolism.Box C/D small nucleolar RNA genes and the Prader-Willi syndrome: a complex interplay.Pyrvinium pamoate changes alternative splicing of the serotonin receptor 2C by influencing its RNA structure.Involvement of serotonin 2C receptor RNA editing in accumbal neuropeptide Y expression and behavioural despair.Serotonergic Control of Metabolic Homeostasis.Evidence for large diversity in the human transcriptome created by Alu RNA editing.Overexpression of 5-HT2C receptors in forebrain leads to elevated anxiety and hypoactivity.
P2860
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P2860
Dysregulated editing of serotonin 2C receptor mRNAs results in energy dissipation and loss of fat mass
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Dysregulated editing of seroto ...... ssipation and loss of fat mass
@en
Dysregulated editing of seroto ...... sipation and loss of fat mass.
@nl
type
label
Dysregulated editing of seroto ...... ssipation and loss of fat mass
@en
Dysregulated editing of seroto ...... sipation and loss of fat mass.
@nl
prefLabel
Dysregulated editing of seroto ...... ssipation and loss of fat mass
@en
Dysregulated editing of seroto ...... sipation and loss of fat mass.
@nl
P2093
P2860
P1476
Dysregulated editing of seroto ...... ssipation and loss of fat mass
@en
P2093
Adda Grimberg
Cedric Mombereau
Julie A Blendy
Kazuko Nishikura
Sarah Teegarden
Tracy L Bale
Yukio Kawahara
P2860
P304
12834-12844
P356
10.1523/JNEUROSCI.3896-08.2008
P407
P577
2008-11-01T00:00:00Z