TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis.
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Intestinal permeability defects: is it time to treat?Infection Strategies of Intestinal Parasite Pathogens and Host Cell ResponsesConceptual barriers to understanding physical barriersIntestinal epithelium in inflammatory bowel diseaseRedeeming an old foe: protective as well as pathophysiological roles for tumor necrosis factor in inflammatory bowel diseaseIntestinal Permeability in Inflammatory Bowel Disease: Pathogenesis, Clinical Evaluation, and Therapy of Leaky GutOccludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux.Hepatic Injury in Nonalcoholic Steatohepatitis Contributes to Altered Intestinal Permeability.Myosin Light Chain Kinase: A Potential Target for Treatment of Inflammatory DiseasesGeniposide ameliorates TNBS-induced experimental colitis in rats via reducing inflammatory cytokine release and restoring impaired intestinal barrier function.ACF7 regulates inflammatory colitis and intestinal wound response by orchestrating tight junction dynamicsTumour necrosis factor superfamily members in the pathogenesis of inflammatory bowel diseaseDietary capsaicin and antibiotics act synergistically to reduce non-alcoholic fatty liver disease induced by high fat diet in mice.A gut microbial metabolite of linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, ameliorates intestinal epithelial barrier impairment partially via GPR40-MEK-ERK pathway.Myosin light chain kinase expression induced via tumor necrosis factor receptor 2 signaling in the epithelial cells regulates the development of colitis-associated carcinogenesis.Vitamin D/VDR signaling pathway ameliorates 2,4,6-trinitrobenzene sulfonic acid-induced colitis by inhibiting intestinal epithelial apoptosisIs intestinal inflammation linking dysbiosis to gut barrier dysfunction during liver disease?Gene expression profiling in non-human primate jejunum, ileum and colon after total-body irradiation: a comparative study of segment-specific molecular and cellular responses.Dietary Fiber Intake is Associated with Increased Colonic Mucosal GPR43+ Polymorphonuclear Infiltration in Active Crohn's DiseaseEpithelial-specific A2B adenosine receptor signaling protects the colonic epithelial barrier during acute colitisMatrix metalloproteinase 9-induced increase in intestinal epithelial tight junction permeability contributes to the severity of experimental DSS colitisAT1R blocker losartan attenuates intestinal epithelial cell apoptosis in a mouse model of Crohn's diseaseBeyond Ussing's chambers: contemporary thoughts on integration of transepithelial transport.Type 3 Muscarinic Receptors Contribute to Clearance of Citrobacter rodentium.Nonmuscle Myosin IIA Regulates Intestinal Epithelial Barrier in vivo and Plays a Protective Role During Experimental ColitisMechanistic roles of epithelial and immune cell signaling during the development of colitis-associated cancer.Salvianolic Acid B Restored Impaired Barrier Function via Downregulation of MLCK by microRNA-1 in Rat Colitis ModelAngelica acutiloba Kitagawa Extract Attenuates DSS-Induced Murine Colitis.Vitamin D treatment attenuates 2,4,6-trinitrobenzene sulphonic acid (TNBS)-induced colitis but not oxazolone-induced colitis.Gluten-induced symptoms in diarrhea-predominant irritable bowel syndrome are associated with increased myosin light chain kinase activity and claudin-15 expression.Pleiotropic functions of TNF-α in the regulation of the intestinal epithelial response to inflammation.Systematic review: thalidomide and thalidomide analogues for treatment of inflammatory bowel disease.Intestinal barrier loss as a critical pathogenic link between inflammatory bowel disease and graft-versus-host disease.Myosin light chain kinase mediates intestinal barrier dysfunction via occludin endocytosis during anoxia/reoxygenation injury.VEN-120, a recombinant human lactoferrin, promotes a regulatory T cell (Treg) phenotype and drives resolution of inflammation in distinct murine models of inflammatory bowel disease.Neutrophil-Epithelial Interactions: A Double-Edged Sword.Recombinant human MFG-E8 ameliorates colon damage in DSS- and TNBS-induced colitis in mice.Molecular pathways driving disease-specific alterations of intestinal epithelial cells.The intestinal epithelial barrier: a therapeutic target?The mucosal barrier at a glance.
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TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on 22 April 2013
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
TNFR2 activates MLCK-dependent ...... loss and experimental colitis.
@en
TNFR2 activates MLCK-dependent ...... loss and experimental colitis.
@nl
type
label
TNFR2 activates MLCK-dependent ...... loss and experimental colitis.
@en
TNFR2 activates MLCK-dependent ...... loss and experimental colitis.
@nl
prefLabel
TNFR2 activates MLCK-dependent ...... loss and experimental colitis.
@en
TNFR2 activates MLCK-dependent ...... loss and experimental colitis.
@nl
P2093
P2860
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P1476
TNFR2 activates MLCK-dependent ...... loss and experimental colitis
@en
P2093
Clara Abraham
Ekaterina A Khramtsova
Emily S Turner
Galina Khramtsova
Gurminder Singh
Jerrold R Turner
Lydia A Breskin
Pei-Yun Tsai
P2860
P304
P356
10.1053/J.GASTRO.2013.04.011
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P50
P577
2013-04-22T00:00:00Z