IDO1 metabolites activate β-catenin signaling to promote cancer cell proliferation and colon tumorigenesis in mice
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Characterization of dextran sodium sulfate-induced inflammation and colonic tumorigenesis in Smad3(-/-) mice with dysregulated TGFβUnderstanding the role of the kynurenine pathway in human breast cancer immunobiologyThe Role of Indoleamine 2, 3-Dioxygenase in Immune Suppression and AutoimmunityTryptophan catabolism restricts IFN-γ-expressing neutrophils and Clostridium difficile immunopathologyTryptophan metabolite activation of the aryl hydrocarbon receptor regulates IL-10 receptor expression on intestinal epitheliaRecent advancement in understanding colitis-associated tumorigenesis.Heme-binding-mediated negative regulation of the tryptophan metabolic enzyme indoleamine 2,3-dioxygenase 1 (IDO1) by IDO2IDO1 and IDO2 non-synonymous gene variants: correlation with crohn's disease risk and clinical phenotype.The gut microbiota in mouse models of inflammatory bowel disease.NPC1L1 knockout protects against colitis-associated tumorigenesis in mice.Methylome profiling reveals functions and genes which are differentially methylated in serrated compared to conventional colorectal carcinoma.Severity of DSS-induced colitis is reduced in Ido1-deficient mice with down-regulation of TLR-MyD88-NF-kB transcriptional networksDysregulated expression of IDO may cause unexplained recurrent spontaneous abortion through suppression of trophoblast cell proliferation and migration.An integrative approach for the identification of prognostic and predictive biomarkers in rectal cancerExpression Pattern and Clinicopathological Relevance of the Indoleamine 2,3-Dioxygenase 1/Tryptophan 2,3-Dioxygenase Protein in Colorectal Cancer.Metabolic control of tumour progression and antitumour immunityProfiling of mRNA and long non-coding RNA of urothelial cancer in recipients after renal transplantation.Therapeutic targeting of inflammation and tryptophan metabolism in colon and gastrointestinal cancer.Parallel Expression of Enzyme Inhibitors of CD8T Cell Activity in Tumor Microenvironments and Secretory Endometrium.Novel therapeutics in metastatic colorectal cancer: molecular insights and pharmacogenomic implications.Role of Dietary Metabolites in Regulating the Host Immune Response in Gastrointestinal Disease.Indoleamine 2,3-dioxygenase 1, Increased in Human Gastric Pre-Neoplasia, Promotes Inflammation and Metaplasia in Mice and is Associated with Type II Hypersensitivity/Autoimmunity.Intestinal epithelial suppressor of cytokine signaling 3 (SOCS3) impacts on mucosal homeostasis in a model of chronic inflammation.Inhibition of indoleamine 2,3-dioxygenase 1 expression alters immune response in colon tumor microenvironment in mice.CD44 and TLR4 mediate hyaluronic acid regulation of Lgr5+ stem cell proliferation, crypt fission, and intestinal growth in postnatal and adult mice.Kynurenine pathway metabolites: relevant to vitamin B-6 deficiency and beyond.Quinolinic acid induces neuritogenesis in SH-SY5Y neuroblastoma cells independently of NMDA receptor activation.Integration of multiple networks and pathways identifies cancer driver genes in pan-cancer analysis.Impact of the Gut Microbiota on Intestinal Immunity Mediated by Tryptophan Metabolism.miR-153 suppresses IDO1 expression and enhances CAR T cell immunotherapy.Obesity and Cancer: Existing and New Hypotheses for a Causal Connection.Trypanosoma cruzi Exploits Wnt Signaling Pathway to Promote Its Intracellular Replication in Macrophages.Indoleamine 2,3-dioxygenase-dependent expansion of T-regulatory cells maintains mucosal healing in ulcerative colitis
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IDO1 metabolites activate β-catenin signaling to promote cancer cell proliferation and colon tumorigenesis in mice
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 10 May 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
IDO1 metabolites activate β-ca ...... nd colon tumorigenesis in mice
@en
IDO1 metabolites activate β-ca ...... d colon tumorigenesis in mice.
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type
label
IDO1 metabolites activate β-ca ...... nd colon tumorigenesis in mice
@en
IDO1 metabolites activate β-ca ...... d colon tumorigenesis in mice.
@nl
prefLabel
IDO1 metabolites activate β-ca ...... nd colon tumorigenesis in mice
@en
IDO1 metabolites activate β-ca ...... d colon tumorigenesis in mice.
@nl
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IDO1 metabolites activate β-ca ...... nd colon tumorigenesis in mice
@en
P2093
Ameet I Thaker
Jeffrey M Marinshaw
Kumar S Bishnupuri
Lynne Foster
M Suprada Rao
Matthew A Ciorba
Thomas A Kerr
William F Stenson
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P304
416-25.e1-4
P356
10.1053/J.GASTRO.2013.05.002
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P577
2013-05-10T00:00:00Z