Salinomycin induces cell death with autophagy through activation of endoplasmic reticulum stress in human cancer cells.
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Salinomycin activates AMP-activated protein kinase-dependent autophagy in cultured osteoblastoma cells: a negative regulator against cell apoptosisInhibition of autophagic flux by salinomycin results in anti-cancer effect in hepatocellular carcinoma cellsSalinomycin induced ROS results in abortive autophagy and leads to regulated necrosis in glioblastomaSalinomycin Exerts Anticancer Effects on PC-3 Cells and PC-3-Derived Cancer Stem Cells In Vitro and In Vivo.Sensitization of cancer cells through reduction of total Akt and downregulation of salinomycin-induced pAkt, pGSk3β, pTSC2, and p4EBP1 by cotreatment with MK-2206.Elastase induces lung epithelial cell autophagy through placental growth factor: a new insight of emphysema pathogenesisSequential Salinomycin Treatment Results in Resistance Formation through Clonal Selection of Epithelial-Like Tumor Cells.EHMT2 inhibitor BIX-01294 induces apoptosis through PMAIP1-USP9X-MCL1 axis in human bladder cancer cellsROS-p53-cyclophilin-D signaling mediates salinomycin-induced glioma cell necrosisCarbon ions induce autophagy effectively through stimulating the unfolded protein response and subsequent inhibiting Akt phosphorylation in tumor cells.Maspin Expression in Prostate Tumor Cells Averts Stemness and Stratifies Drug Sensitivity.p8 attenuates the apoptosis induced by dihydroartemisinin in cancer cells through promoting autophagyResveratrol analogue 3,4,4'-trihydroxy-trans-stilbene induces apoptosis and autophagy in human non-small-cell lung cancer cells in vitro.Simultaneous inhibition of the ubiquitin-proteasome system and autophagy enhances apoptosis induced by ER stress aggravators in human pancreatic cancer cells.Inhibition of ERα/ERK/P62 cascades induces "autophagic switch" in the estrogen receptor-positive breast cancer cells exposed to gemcitabineLow-dose salinomycin induces anti-leukemic responses in AML and MLL.Role of Autophagy and Apoptosis in Non-Small-Cell Lung Cancer.Untangling knots between autophagic targets and candidate drugs, in cancer therapy.Apoptotic and autophagic pathways with relevant small-molecule compounds, in cancer stem cells.Radiation-induced autophagy: mechanisms and consequences.Salinomycin efficiency assessment in non-tumor (HB4a) and tumor (MCF-7) human breast cells.The anticancer effect of chaetocin is enhanced by inhibition of autophagy.A novel derivative of tetrandrine (H1) induces endoplasmic reticulum stress-mediated apoptosis and prosurvival autophagy in human non-small cell lung cancer cells.Neferine induces autophagy of human ovarian cancer cells via p38 MAPK/ JNK activation.Bevacizumab induces A549 cell apoptosis through the mechanism of endoplasmic reticulum stress in vitro.Endoplasmic reticulum stress and cell death in mTORC1-overactive cells is induced by nelfinavir and enhanced by chloroquine.Salinomycin: A new paradigm in cancer therapy.Afatinib down-regulates MCL-1 expression through the PERK-eIF2α-ATF4 axis and leads to apoptosis in head and neck squamous cell carcinomaPterostilbene exerts anticancer activity on non-small-cell lung cancer via activating endoplasmic reticulum stress.Targeting protein homeostasis with nelfinavir/salinomycin dual therapy effectively induces death of mTORC1 hyperactive cells.Tumor acidosis enhances cytotoxic effects and autophagy inhibition by salinomycin on cancer cell lines and cancer stem cellsEndoplasmic reticulum stress-inducing drugs sensitize glioma cells to temozolomide through downregulation of MGMT, MPG, and Rad51Inhibition of TRB3 Protects Photoreceptors against Endoplasmic Reticulum Stress-Induced Apoptosis after Experimental Retinal Detachment.Reversal of the Apoptotic Resistance of Non-Small-Cell Lung Carcinoma towards TRAIL by Natural Product Toosendanin.Dual targeting of androgen receptor and mTORC1 by salinomycin in prostate cancer.Ionophore Antibiotics as Cancer Stem Cell-Selective Drugs: Open Questions.Salinomycin kills cancer stem cells by sequestering iron in lysosomes.Salinomycin, as an autophagy modulator-- a new avenue to anticancer: a review.Lup-20(29)-en-3β,28-di-yl-nitrooxy acetate affects MCF-7 proliferation through the crosstalk between apoptosis and autophagy in mitochondria.Endoplasmic reticulum stress-mediated autophagy protects against β,β-dimethylacrylshikonin-induced apoptosis in lung adenocarcinoma cells.
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Salinomycin induces cell death with autophagy through activation of endoplasmic reticulum stress in human cancer cells.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 18 April 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Salinomycin induces cell death ...... stress in human cancer cells.
@en
Salinomycin induces cell death ...... stress in human cancer cells.
@nl
type
label
Salinomycin induces cell death ...... stress in human cancer cells.
@en
Salinomycin induces cell death ...... stress in human cancer cells.
@nl
prefLabel
Salinomycin induces cell death ...... stress in human cancer cells.
@en
Salinomycin induces cell death ...... stress in human cancer cells.
@nl
P2093
P2860
P356
P1433
P1476
Salinomycin induces cell death ...... m stress in human cancer cells
@en
P2093
Diansheng Zhong
Ning Zhong
Sunil Singhal
Tianliang Li
P2860
P304
P356
10.4161/AUTO.24632
P577
2013-04-18T00:00:00Z