Single chain variable fragment antibodies block aggregation and toxicity induced by familial ALS-linked mutant forms of SOD1.
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Antibodies inside of a cell can change its outside: Can intrabodies provide a new therapeutic paradigm?Single-chain fragment variable passive immunotherapies for neurodegenerative diseases.Parkin Protects Against Misfolded SOD1 Toxicity by Promoting Its Aggresome Formation and Autophagic Clearance.A computational combinatorial approach identifies a protein inhibitor of superoxide dismutase 1 misfolding, aggregation, and cytotoxicity.
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Single chain variable fragment antibodies block aggregation and toxicity induced by familial ALS-linked mutant forms of SOD1.
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article scientifique
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bilimsel makale
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scientific article published on 20 April 2013
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vedecký článok
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vetenskaplig artikel
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Single chain variable fragment ...... S-linked mutant forms of SOD1.
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Single chain variable fragment ...... S-linked mutant forms of SOD1.
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label
Single chain variable fragment ...... S-linked mutant forms of SOD1.
@en
Single chain variable fragment ...... S-linked mutant forms of SOD1.
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prefLabel
Single chain variable fragment ...... S-linked mutant forms of SOD1.
@en
Single chain variable fragment ...... S-linked mutant forms of SOD1.
@nl
P2093
P2860
P1476
Single chain variable fragment ...... S-linked mutant forms of SOD1.
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P2093
Brian K Kay
Ghanashyam D Ghadge
John D Pavlovic
Raymond P Roos
Sujatha P Koduvayur
P2860
P356
10.1016/J.NBD.2013.04.007
P577
2013-04-20T00:00:00Z