The Autophagy-Lysosomal Pathway in Neurodegeneration: A TFEB Perspective
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Long-term exposure to 835 MHz RF-EMF induces hyperactivity, autophagy and demyelination in the cortical neurons of mice.FoxO1 interacts with transcription factor EB and differentially regulates mitochondrial uncoupling proteins via autophagy in adipocytesHinokitiol protects primary neuron cells against prion peptide-induced toxicity via autophagy flux regulated by hypoxia inducing factor-1.Regulation of morphine-induced synaptic alterations: Role of oxidative stress, ER stress, and autophagy.Hypericin-mediated sonodynamic therapy induces autophagy and decreases lipids in THP-1 macrophage by promoting ROS-dependent nuclear translocation of TFEB.Enhancing lysosomal biogenesis and autophagic flux by activating the transcription factor EB protects against cadmium-induced neurotoxicity.Thioredoxin-interacting protein induced α-synuclein accumulation via inhibition of autophagic flux: Implications for Parkinson's disease.Emerging pathways driving early synaptic pathology in Alzheimer's disease.Autophagy facilitates macrophage depots of sustained-release nanoformulated antiretroviral drugsRecent progress on curcumin-based therapeutics: a patent review (2012-2016). Part II: curcumin derivatives in cancer and neurodegeneration.Amyloid precursor protein and endosomal-lysosomal dysfunction in Alzheimer's disease: inseparable partners in a multifactorial disease.The spread of prion-like proteins by lysosomes and tunneling nanotubes: Implications for neurodegenerative diseases.Cigarette smoke induced autophagy-impairment regulates AMD pathogenesis mechanisms in ARPE-19 cells.Intracellular Proteolysis of Progranulin Generates Stable, Lysosomal Granulins that Are Haploinsufficient in Patients with Frontotemporal Dementia Caused by GRN Mutations.Augmenting autophagy for prognosis based intervention of COPD-pathophysiology.Master Autophagy Regulator Transcription Factor EB Regulates Cigarette Smoke-Induced Autophagy Impairment and Chronic Obstructive Pulmonary Disease-Emphysema Pathogenesis.Clinical Implications of the Autophagy Core Gene Variations in Advanced Lung Adenocarcinoma Treated with Gefitinib.Autophagy impairment in Parkinson's disease.Dysregulation of autophagy as a common mechanism in lysosomal storage diseases.Exposure to 835 MHz radiofrequency electromagnetic field induces autophagy in hippocampus but not in brain stem of mice.The role S-nitrosylation in manganese-induced autophagy dysregulation in SH-SY5Y cells.Mask mitigates MAPT- and FUS-induced degeneration by enhancing autophagy through lysosomal acidification.STUB1 regulates TFEB-induced autophagy-lysosome pathway.An adverse outcome pathway for parkinsonian motor deficits associated with mitochondrial complex I inhibition.Heat Shock Proteins and Autophagy Pathways in Neuroprotection: from Molecular Bases to Pharmacological Interventions.Cyclodextrin has conflicting actions on autophagy flux in vivo in brains of normal and Alzheimer model mice.HDAC6 Inhibition Promotes Transcription Factor EB Activation and Is Protective in Experimental Kidney Disease.Impaired autophagic flux is associated with the severity of trauma and the role of A2AR in brain cells after traumatic brain injury.The E3 ubiquitin ligase STUB1 regulates autophagy and mitochondrial biogenesis by modulating TFEB activity.Age-related endolysosome dysfunction in the rat urothelium.TFEB, a potential therapeutic target for osteoarthritis via autophagy regulation
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The Autophagy-Lysosomal Pathway in Neurodegeneration: A TFEB Perspective
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 08 March 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The Autophagy-Lysosomal Pathway in Neurodegeneration: A TFEB Perspective
@en
The Autophagy-Lysosomal Pathway in Neurodegeneration: A TFEB Perspective.
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type
label
The Autophagy-Lysosomal Pathway in Neurodegeneration: A TFEB Perspective
@en
The Autophagy-Lysosomal Pathway in Neurodegeneration: A TFEB Perspective.
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prefLabel
The Autophagy-Lysosomal Pathway in Neurodegeneration: A TFEB Perspective
@en
The Autophagy-Lysosomal Pathway in Neurodegeneration: A TFEB Perspective.
@nl
P2093
P2860
P1476
The Autophagy-Lysosomal Pathway in Neurodegeneration: A TFEB Perspective
@en
P2093
Andrea Ballabio
Heidi Martini-Stoica
P2860
P304
P356
10.1016/J.TINS.2016.02.002
P577
2016-03-08T00:00:00Z