Projecting the performance of risk prediction based on polygenic analyses of genome-wide association studies.
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The mathematical limits of genetic prediction for complex chronic diseaseAnalysis of heritability and shared heritability based on genome-wide association studies for thirteen cancer typesPathogenesis of coronary artery disease: focus on genetic risk factors and identification of genetic variantsPolygenic EpidemiologyThe Genetics of Stress-Related Disorders: PTSD, Depression, and Anxiety DisordersGenome-wide association study of paliperidone efficacyRoutes for breaching and protecting genetic privacyWinner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level DataDissecting the genetics of complex traits using summary association statisticsDeveloping and evaluating polygenic risk prediction models for stratified disease prevention.Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease.Regularized Machine Learning in the Genetic Prediction of Complex TraitsThe role of functional data in interpreting the effects of genetic variationA new tool called DISSECT for analysing large genomic data sets using a Big Data approach.Reclassification of genetic-based risk predictions as GWAS data accumulate.Environmental risk score as a new tool to examine multi-pollutants in epidemiologic research: an example from the NHANES study using serum lipid levels.Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies.Polygenic type 2 diabetes prediction at the limit of common variant detectionPrediction of gene expression with cis-SNPs using mixed models and regularization methodsWhat Does "Precision Medicine" Have to Say About Prevention?Applying compressed sensing to genome-wide association studiesPitfalls of predicting complex traits from SNPs.Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development.A population-based study of genetic variation and psychotic experiences in adolescents.Clinical implications of shared genetics and pathogenesis in autoimmune diseases.Quantifying missing heritability at known GWAS loci.Research review: Polygenic methods and their application to psychiatric traits.Genomic prediction of complex human traits: relatedness, trait architecture and predictive meta-models.Leveraging population admixture to characterize the heritability of complex traits.Testing calibration of risk models at extremes of disease riskMost common 'sporadic' cancers have a significant germline genetic component.Genetic and environmental components of family history in type 2 diabetes.Novel genetic analysis for case-control genome-wide association studies: quantification of power and genomic prediction accuracy.Shroom3 contributes to the maintenance of the glomerular filtration barrier integrityEnhanced methods for local ancestry assignment in sequenced admixed individuals.Polygenic risk, stressful life events and depressive symptoms in older adults: a polygenic score analysis.Simultaneous discovery, estimation and prediction analysis of complex traits using a bayesian mixture modelA model to determine colorectal cancer risk using common genetic susceptibility lociPowerful Tukey's One Degree-of-Freedom Test for Detecting Gene-Gene and Gene-Environment InteractionsRisk Analysis of Prostate Cancer in PRACTICAL, a Multinational Consortium, Using 25 Known Prostate Cancer Susceptibility Loci.
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Projecting the performance of risk prediction based on polygenic analyses of genome-wide association studies.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 03 March 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Projecting the performance of ...... nome-wide association studies.
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Projecting the performance of ...... nome-wide association studies.
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type
label
Projecting the performance of ...... nome-wide association studies.
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Projecting the performance of ...... nome-wide association studies.
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prefLabel
Projecting the performance of ...... nome-wide association studies.
@en
Projecting the performance of ...... nome-wide association studies.
@nl
P2093
P2860
P50
P356
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Projecting the performance of ...... nome-wide association studies.
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P2093
Bill Wheeler
Joshua Sampson
Ju-Hyun Park
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P2888
P304
400-5, 405e1-3
P356
10.1038/NG.2579
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P577
2013-03-03T00:00:00Z
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P6179
1020935195