Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis
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Enzyme characteristics of pathogen-specific trehalose-6-phosphate phosphatasesTrehalose pathway as an antifungal target.Central Role of the Trehalose Biosynthesis Pathway in the Pathogenesis of Human Fungal Infections: Opportunities and Challenges for Therapeutic Development.The antifungal pipeline: a reality check.Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design.Structure of a fungal form of aspartate-semialdehyde dehydrogenase from Aspergillus fumigatus.Crystal structure of an ASCH protein from Zymomonas mobilis and its ribonuclease activity specific for single-stranded RNA.New Horizons in Antifungal Therapy.Cloning and expression analysis of tps, and cryopreservation research of trehalose from Antarctic strain Pseudozyma sp.Trehalose-6-phosphate phosphatase as a broad-spectrum therapeutic target against eukaryotic and prokaryotic pathogens
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Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 15 June 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Structures of trehalose-6-phos ...... rate recognition and catalysis
@en
Structures of trehalose-6-phos ...... ate recognition and catalysis.
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type
label
Structures of trehalose-6-phos ...... rate recognition and catalysis
@en
Structures of trehalose-6-phos ...... ate recognition and catalysis.
@nl
prefLabel
Structures of trehalose-6-phos ...... rate recognition and catalysis
@en
Structures of trehalose-6-phos ...... ate recognition and catalysis.
@nl
P2093
P2860
P356
P1476
Structures of trehalose-6-phos ...... rate recognition and catalysis
@en
P2093
Dena L Toffaletti
Erica J Washington
Jennifer L Tenor
Maria A Schumacher
Richard E Lee
Richard G Brennan
William R Shadrick
P2860
P304
P356
10.1073/PNAS.1601774113
P407
P577
2016-06-15T00:00:00Z