LIM only 4 is overexpressed in late stage pancreas cancer - Wikidata - wikimedia - TriplyDB

LIM only 4 is overexpressed in late stage pancreas cancer

LIM only 4 is overexpressed in late stage pancreas cancer

http://www.wikidata.org/entity/Q37066190

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MicroRNA, hsa-miR-200c, is an independent prognostic factor in pancreatic cancer and its upregulation inhibits pancreatic cancer invasion but increases cell proliferation.MicroRNA alterations of pancreatic intraepithelial neoplasias Necdin, a p53-target gene, is an inhibitor of p53-mediated growth arrest.Differential expression profiling analyses identifies downregulation of 1p, 6q, and 14q genes and overexpression of 6p histone cluster 1 genes as markers of recurrence in meningiomas.Aberrant expression of LMO4 induces centrosome amplification and mitotic spindle abnormalities in breast cancer cells.The oncoprotein HBXIP activates transcriptional coregulatory protein LMO4 via Sp1 to promote proliferation of breast cancer cells.LMO4 is a prognostic marker involved in cell migration and invasion in non-small-cell lung cancer.LIM-domain-only proteins: multifunctional nuclear transcription coregulators that interacts with diverse proteins.Preliminary screening of differentially expressed genes involved in methyl-CpG-binding protein 2 gene-mediated proliferation in human osteosarcoma cells.Insig2 is overexpressed in pancreatic cancer and its expression is induced by hypoxia.The LIM-domain only protein 4 contributes to lung epithelial cell proliferation but is not essential for tumor progression.The LIM adaptor protein LMO4 is an essential regulator of neural crest development.LMO4 modulates proliferation and differentiation of 3T3-L1 preadipocytes.LMO4 mediates trastuzumab resistance in HER2 positive breast cancer cells.

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LIM only 4 is overexpressed in late stage pancreas cancer

http://www.wikidata.org/entity/Q37066190

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 22 December 2008

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

LIM only 4 is overexpressed in late stage pancreas cancer

@en

LIM only 4 is overexpressed in late stage pancreas cancer.

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label

LIM only 4 is overexpressed in late stage pancreas cancer

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LIM only 4 is overexpressed in late stage pancreas cancer.

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prefLabel

LIM only 4 is overexpressed in late stage pancreas cancer

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LIM only 4 is overexpressed in late stage pancreas cancer.

@nl

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Molecular Cancer

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LIM only 4 is overexpressed in late stage pancreas cancer

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Hayato Fujita

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Hidehisa Kitada

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Hiroshi Yamaguchi

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Jun Yu

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Kazuhiro Mizumoto

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Kohei Nakata

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Lin Cui

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Masao Tanaka

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Takuya Egami

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P2860

Molecular cloning of LMO41, a new human LIM domain gene

The LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activity

TTG-2, a new gene encoding a cysteine-rich protein with the LIM motif, is overexpressed in acute T-cell leukaemia with the t(11;14)(p13;q11)

Overexpression of LMO4 induces mammary hyperplasia, promotes cell invasion, and is a predictor of poor outcome in breast cancer

The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13

Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers

Identification and characterization of LMO4, an LMO gene with a novel pattern of expression during embryogenesis

STK11/LKB1 Peutz-Jeghers gene inactivation in intraductal papillary-mucinous neoplasms of the pancreas

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase

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93

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scholarly article

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10.1186/1476-4598-7-93

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7

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Kenoki Ohuchida

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2008-12-22T00:00:00Z

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23681144

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1027486541

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19099607

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