Distinct roles of STAT3 and STAT5 in the pathogenesis and targeted therapy of breast cancer.
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STAT3 and epithelial-mesenchymal transitions in carcinomasSTAT3 Activity and Function in Cancer: Modulation by STAT5 and miR-146b.Alteration of SHP-1/p-STAT3 Signaling: A Potential Target for Anticancer Therapy.Involvement of the janus kinase/signal transducer and activator of transcription signaling pathway in multiple sclerosis and the animal model of experimental autoimmune encephalomyelitis.Genetic variation in the JAK/STAT/SOCS signaling pathway influences breast cancer-specific mortality through interaction with cigarette smoking and use of aspirin/NSAIDs: the Breast Cancer Health Disparities Study.Nifuroxazide induces apoptosis and impairs pulmonary metastasis in breast cancer model.The Status of STAT3 and STAT5 in Human Breast Atypical Ductal Hyperplasia.Novel iodoacetamido benzoheterocyclic derivatives with potent antileukemic activity are inhibitors of STAT5 phosphorylation.Constitutive activation of STAT3 in breast cancer cells: A review.Rationally Repurposing Ruxolitinib (Jakafi (®)) as a Solid Tumor TherapeuticRuxolitinib synergizes with DMF to kill via BIM+BAD-induced mitochondrial dysfunction and via reduced SOD2/TRX expression and ROSProlactin-Stat5 signaling in breast cancer is potently disrupted by acidosis within the tumor microenvironment.Inhibition of Stat3 signaling pathway by nifuroxazide improves antitumor immunity and impairs colorectal carcinoma metastasis.ΔNp63 activates EGFR signaling to induce loss of adhesion in triple-negative basal-like breast cancer cells.The tyrosine kinase inhibitor nintedanib activates SHP-1 and induces apoptosis in triple-negative breast cancer cells.An anti-cancer WxxxE-containing azurin polypeptide inhibits Rac1-dependent STAT3 and ERK/GSK-3β signaling in breast cancer cells.Adaptor proteins NUMB and NUMBL promote cell cycle withdrawal by targeting ERBB2 for degradation.Stat5 Exerts Distinct, Vital Functions in the Cytoplasm and Nucleus of Bcr-Abl+ K562 and Jak2(V617F)+ HEL Leukemia Cells.Nanomolar-Potency Small Molecule Inhibitor of STAT5 Protein.Ligand-induced STAT3 signaling increases at relapse and is associated with outcome in pediatric acute myeloid leukemia: a report from the Children's Oncology Group.Targeting Oncogenic Transcription Factors: Therapeutic Implications of Endogenous STAT Inhibitors.Sequential combination of docetaxel with a SHP-1 agonist enhanced suppression of p-STAT3 signaling and apoptosis in triple negative breast cancer cells.FYN promotes mesenchymal phenotypes of basal type breast cancer cells through STAT5/NOTCH2 signaling node.Hyperprolactinemia-inducing antipsychotics increase breast cancer risk by activating JAK-STAT5 in precancerous lesions.Long-term exposure to carcinoma-associated fibroblasts makes breast cancer cells addictive to integrin β1.The STAT3 Target Gene TNFRSF1A Modulates the NF-κB Pathway in Breast Cancer Cells.[The Role of SOCS in the Development of Tumors].Implications of STAT3 and STAT5 signaling on gene regulation and chromatin remodeling in hematopoietic cancer
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Distinct roles of STAT3 and STAT5 in the pathogenesis and targeted therapy of breast cancer.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 24 March 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Distinct roles of STAT3 and ST ...... eted therapy of breast cancer.
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Distinct roles of STAT3 and ST ...... eted therapy of breast cancer.
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type
label
Distinct roles of STAT3 and ST ...... eted therapy of breast cancer.
@en
Distinct roles of STAT3 and ST ...... eted therapy of breast cancer.
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prefLabel
Distinct roles of STAT3 and ST ...... eted therapy of breast cancer.
@en
Distinct roles of STAT3 and ST ...... eted therapy of breast cancer.
@nl
P2093
P2860
P1476
Distinct roles of STAT3 and ST ...... eted therapy of breast cancer.
@en
P2093
David A Frank
Michael Xiang
Sarah R Walker
P2860
P304
P356
10.1016/J.MCE.2013.03.010
P577
2013-03-24T00:00:00Z