Stereoselective excision of thymine glycol from oxidatively damaged DNA.
about
Variant base excision repair proteins: contributors to genomic instabilityThe crystal structure of human endonuclease VIII-like 1 (NEIL1) reveals a zincless finger motif required for glycosylase activitySynthesis and characterization of oligonucleotides containing 2'-fluorinated thymidine glycol as inhibitors of the endonuclease III reactionPreferential formation of (5S,6R)-thymine glycol for oligodeoxyribonucleotide synthesis and analysis of drug binding to thymine glycol-containing DNA.Base excision repair and cancerThe cis -(5 R ,6 S )-Thymine Glycol Lesion Occupies the Wobble Position When Mismatched with Deoxyguanosine in DNABinding of the human nucleotide excision repair proteins XPA and XPC/HR23B to the 5R-thymine glycol lesion and structure of the cis-(5R,6S) thymine glycol epimer in the 5'-GTgG-3' sequence: destabilization of two base pairs at the lesion siteDifferential specificity of human and Escherichia coli endonuclease III and VIII homologues for oxidative base lesionsThe oxidative DNA glycosylases of Mycobacterium tuberculosis exhibit different substrate preferences from their Escherichia coli counterpartsError-Prone Translesion DNA Synthesis by Escherichia coli DNA Polymerase IV (DinB) on Templates Containing 1,2-dihydro-2-oxoadenineRecent advances in the structural mechanisms of DNA glycosylasesNeil3 and NEIL1 DNA glycosylases remove oxidative damages from quadruplex DNA and exhibit preferences for lesions in the telomeric sequence context.Three novel NEIL1 promoter polymorphisms in gastric cancer patientsInterplay between DNA repair and inflammation, and the link to cancerRepair of mitochondrial DNA in aging and carcinogenesis.'To repair or not to repair - no longer a question': repair of mitochondrial DNA shielding against age and cancer.Mitochondrial DNA damage and the aging process: facts and imaginations.Tolerance for 8-oxoguanine but not thymine glycol in alignment-based gap filling of partially complementary double-strand break ends by DNA polymerase lambda in human nuclear extracts.Lesion specificity in the base excision repair enzyme hNeil1: modeling and dynamics studies.Tautomerization-dependent recognition and excision of oxidation damage in base-excision DNA repair.Photochemical control of DNA structure through radical disproportionation.DNA base repair--recognition and initiation of catalysis.Chemistry and structural biology of DNA damage and biological consequencesBoron and nucleic acid chemistries: merging the best of both worlds.Occurrence, Biological Consequences, and Human Health Relevance of Oxidative Stress-Induced DNA Damage.Base Excision Repair of N6-Deoxyadenosine Adducts of 1,3-Butadiene.Hypersensitivity of mouse NEIL1-knockdown cells to hydrogen peroxide during S phase.Stimulation of N--glycoside transfer in deoxythymidine glycol: mechanism of the initial step in base excision repair.Processing of thymine glycol in a clustered DNA damage site: mutagenic or cytotoxic.Catalytic mechanism of Escherichia coli endonuclease VIII: roles of the intercalation loop and the zinc fingerInterconversion of the cis-5R,6S- and trans-5R,6R-thymine glycol lesions in duplex DNA.Detection of DNA damage: effect of thymidine glycol residues on the thermodynamic, substrate and interfacial acoustic properties of oligonucleotide duplexes.Synthesis of a convenient thymidine glycol phosphoramidite monomer and its site-specific incorporation into DNA fragments.Probing the activity of NTHL1 orthologs by targeting conserved amino acid residues.
P2860
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P2860
Stereoselective excision of thymine glycol from oxidatively damaged DNA.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 15 January 2004
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vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Stereoselective excision of thymine glycol from oxidatively damaged DNA.
@en
Stereoselective excision of thymine glycol from oxidatively damaged DNA.
@nl
type
label
Stereoselective excision of thymine glycol from oxidatively damaged DNA.
@en
Stereoselective excision of thymine glycol from oxidatively damaged DNA.
@nl
prefLabel
Stereoselective excision of thymine glycol from oxidatively damaged DNA.
@en
Stereoselective excision of thymine glycol from oxidatively damaged DNA.
@nl
P2093
P2860
P356
P1476
Stereoselective excision of thymine glycol from oxidatively damaged DNA.
@en
P2093
Andrea S Fernandes
Arthur P Grollman
Charles R Iden
Elena Zaika
M Cecilia Torres
Maryann Wente
Monica M McTigue
P2860
P304
P356
10.1093/NAR/GKH190
P407
P50
P577
2004-01-15T00:00:00Z