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VHZ is a novel centrosomal phosphatase associated with cell growth and human primary cancersPhosphatase of regenerating liver 2 (PRL2) is essential for placental development by down-regulating PTEN (Phosphatase and Tensin Homologue Deleted on Chromosome 10) and activating Akt proteinProtein tyrosine phosphatases--from housekeeping enzymes to master regulators of signal transductionCross talk between receptor guanylyl cyclase C and c-src tyrosine kinase regulates colon cancer cell cytostasisDrosophila PRL-1 is a growth inhibitor that counteracts the function of the Src oncogenePRL-1 Protein Promotes ERK1/2 and RhoA Protein Activation through a Non-canonical Interaction with the Src Homology 3 Domain of p115 Rho GTPase-activating ProteinProcyanidins Negatively Affect the Activity of the Phosphatases of Regenerating LiverIdentification of a novel prenyl and palmitoyl modification at the CaaX motif of Cdc42 that regulates RhoGDI bindingInvestigational inhibitors of PTP4A3 phosphatase as antineoplastic agents.Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.Identification of candidate growth promoting genes in ovarian cancer through integrated copy number and expression analysis.PRL2/PTP4A2 phosphatase is important for hematopoietic stem cell self-renewal.Therapeutic potential of PRL-3 targeting and clinical significance of PRL-3 genomic amplification in gastric cancerPRL-3 promotes telomere deprotection and chromosomal instability.Oncogenic function and prognostic significance of protein tyrosine phosphatase PRL-1 in hepatocellular carcinomaPhosphatase of regenerating liver-1 promotes cell migration and invasion and regulates filamentous actin dynamics.VEGF promotes the transcription of the human PRL-3 gene in HUVEC through transcription factor MEF2CProtein tyrosine phosphatases as potential therapeutic targets.Pathogenetic mechanisms in gastric cancer.Phosphatase of regenerating liver: a novel target for cancer therapy.Genomic and genetic alterations influence the progression of gastric cancer.PRL-3 suppresses c-Fos and integrin α2 expression in ovarian cancer cells.Protein tyrosine phosphatase 4A2 expression predicts overall and disease-free survival of human breast cancer and is associated with estrogen and progestin receptor status.Expression of phosphatase of regenerating liver family genes during embryogenesis: an evolutionary developmental analysis among Drosophila, amphioxus, and zebrafishSrc-mediated phosphorylation of the tyrosine phosphatase PRL-3 is required for PRL-3 promotion of Rho activation, motility and invasionMiR-339-5p regulates the growth, colony formation and metastasis of colorectal cancer cells by targeting PRL-1Targeting protein tyrosine phosphatases for anticancer drug discovery.Poor prognosis of phosphatase of regenerating liver 3 expression in gastric cancer: a meta-analysis.Membrane protein CNNM4-dependent Mg2+ efflux suppresses tumor progressionPRL-3 mediates the protein maturation of ULBP2 by regulating the tyrosine phosphorylation of HSP60Biochemical evaluation of virtual screening methods reveals a cell-active inhibitor of the cancer-promoting phosphatases of regenerating liver.Engineering the first chimeric antibody in targeting intracellular PRL-3 oncoprotein for cancer therapy in mice.PRL-3 activates mTORC1 in Cancer Progression.Integrative DNA methylome analysis of pan-cancer biomarkers in cancer discordant monozygotic twin-pairsMicroRNA-495 downregulates FOXC1 expression to suppress cell growth and migration in endometrial cancer.PRL-3 promotes cell adhesion by interacting with JAM2 in colon cancer.Oncogenic roles of PRL-3 in FLT3-ITD induced acute myeloid leukaemia.PRL-3 promotes the peritoneal metastasis of gastric cancer through the PI3K/Akt signaling pathway by regulating PTEN.PRL3-zumab, a first-in-class humanized antibody for cancer therapy.Role of phosphatase of regenerating liver 1 (PRL1) in spermatogenesis.
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description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
PRL PTPs: mediators and markers of cancer progression.
@en
PRL PTPs: mediators and markers of cancer progression.
@nl
type
label
PRL PTPs: mediators and markers of cancer progression.
@en
PRL PTPs: mediators and markers of cancer progression.
@nl
prefLabel
PRL PTPs: mediators and markers of cancer progression.
@en
PRL PTPs: mediators and markers of cancer progression.
@nl
P2860
P1476
PRL PTPs: mediators and markers of cancer progression.
@en
P2093
Darrell C Bessette
P2860
P2888
P304
P356
10.1007/S10555-008-9121-3
P577
2008-06-01T00:00:00Z