Perichondrium phenotype and border function are regulated by Ext1 and heparan sulfate in developing long bones: a mechanism likely deranged in Hereditary Multiple Exostoses.
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Human genetic disorders and knockout mice deficient in glycosaminoglycanHeparan sulfate in skeletal development, growth, and pathology: the case of hereditary multiple exostosesHIF-1-PHD2 axis controls expression of syndecan 4 in nucleus pulposus cells.Unsuspected osteochondroma-like outgrowths in the cranial base of Hereditary Multiple Exostoses patients and modeling and treatment with a BMP antagonist in mice.Bone Size and Quality Regulation: Concerted Actions of mTOR in Mesenchymal Stromal Cells and OsteoclastsMouse limb skeletal growth and synovial joint development are coordinately enhanced by Kartogenin.FGFR3 Deficiency Causes Multiple Chondroma-like Lesions by Upregulating Hedgehog Signaling.Heparanase stimulates chondrogenesis and is up-regulated in human ectopic cartilage: a mechanism possibly involved in hereditary multiple exostoses.Skeletal maturity of children with multiple osteochondromas: is diminished stature due to a systemic influence?NFAT restricts osteochondroma formation from entheseal progenitorsGenetics of breast cancer bone metastasis: a sequential multistep pattern.Hereditary Multiple Exostoses: New Insights into Pathogenesis, Clinical Complications, and Potential Treatments.Multiple hereditary exostoses (MHE): elucidating the pathogenesis of a rare skeletal disorder through interdisciplinary research.Targeting heparin and heparan sulfate protein interactions.HhAntag, a Hedgehog Signaling Antagonist, Suppresses Chondrogenesis and Modulates Canonical and Non-Canonical BMP Signaling.Aberrant perichondrial BMP signaling mediates multiple osteochondromagenesis in miceImmunohistochemical Localization of Bone Morphogenetic Proteins (BMPs) and their Receptors in Solitary and Multiple Human OsteochondromasEpiphyseal abnormalities, trabecular bone loss and articular chondrocyte hypertrophy develop in the long bones of postnatal Ext1-deficient mice.Advances in the pathogenesis and possible treatments for multiple hereditary exostoses from the 2016 international MHE conference.The pathogenic roles of heparan sulfate deficiency in hereditary multiple exostoses.Palovarotene Inhibits Osteochondroma Formation in a Mouse Model of Multiple Hereditary Exostoses.Chondrogenesis of embryonic limb bud cells in micromass culture progresses rapidly to hypertrophy and is modulated by hydrostatic pressure.Heparan sulfate antagonism alters bone morphogenetic protein signaling and receptor dynamics, suggesting a mechanism in Hereditary Multiple Exostoses.
P2860
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P2860
Perichondrium phenotype and border function are regulated by Ext1 and heparan sulfate in developing long bones: a mechanism likely deranged in Hereditary Multiple Exostoses.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on March 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Perichondrium phenotype and bo ...... Hereditary Multiple Exostoses.
@en
Perichondrium phenotype and bo ...... Hereditary Multiple Exostoses.
@nl
type
label
Perichondrium phenotype and bo ...... Hereditary Multiple Exostoses.
@en
Perichondrium phenotype and bo ...... Hereditary Multiple Exostoses.
@nl
prefLabel
Perichondrium phenotype and bo ...... Hereditary Multiple Exostoses.
@en
Perichondrium phenotype and bo ...... Hereditary Multiple Exostoses.
@nl
P2093
P2860
P1476
Perichondrium phenotype and bo ...... Hereditary Multiple Exostoses.
@en
P2093
Christina Mundy
Eiki Koyama
Federica Sgariglia
Julianne Huegel
Maurizio Pacifici
Patrik Nygren
Paul C Billings
Yu Yamaguchi
P2860
P304
P356
10.1016/J.YDBIO.2013.02.008
P407
P577
2013-03-01T00:00:00Z