Phase I and pharmacokinetic studies of erlotinib administered concurrently with radiotherapy for children, adolescents, and young adults with high-grade glioma. - Wikidata - wikimedia - TriplyDB

Phase I and pharmacokinetic studies of erlotinib administered concurrently with radiotherapy for children, adolescents, and young adults with high-grade glioma.

Phase I and pharmacokinetic studies of erlotinib administered concurrently with radiotherapy for children, adolescents, and young adults with high-grade glioma.

http://www.wikidata.org/entity/Q37069238

about

New chemotherapy strategies and biological agents in the treatment of childhood ependymoma Molecular Biology in Pediatric High-Grade Glioma: Impact on Prognosis and Treatment Radiotherapy and "new" drugs-new side effects?Clinical, radiological, histological and molecular characteristics of paediatric epithelioid glioblastoma Differences in molecular genetics between pediatric and adult malignant astrocytomas: age matters.Management of diffuse pontine gliomas in children: recent developments.Role of ATP-binding cassette and solute carrier transporters in erlotinib CNS penetration and intracellular accumulation.Innovative Therapies for Children with Cancer pediatric phase I study of erlotinib in brainstem glioma and relapsing/refractory brain tumors Enhanced efficacy of IGF1R inhibition in pediatric glioblastoma by combinatorial targeting of PDGFRα/β.Management of high-grade gliomas in the pediatric patient: Past, present, and future.Growth-factor-driven rescue to receptor tyrosine kinase (RTK) inhibitors through Akt and Erk phosphorylation in pediatric low grade astrocytoma and ependymoma Inhibition of Pediatric Glioblastoma Tumor Growth by the Anti-Cancer Agent OKN-007 in Orthotopic Mouse Xenografts.Molecular profiling of childhood cancer: Biomarkers and novel therapies Advances in paediatric cancer treatment Breast cancer subtypes: response to radiotherapy and potential radiosensitisation.Neurotoxicity of biologically targeted agents in pediatric cancer trials Combining molecular targeted agents with radiation therapy for malignant gliomas Pharmacokinetics of erlotinib for the treatment of high-grade glioma in a pediatric patient with cystic fibrosis: case report and review of the literature.Pediatric brain tumors: current treatment strategies and future therapeutic approaches Paediatric high and low grade glioma: the impact of tumour biology on current and future therapy.Nimotuzumab in pediatric glioma.A review of erlotinib--an oral, selective epidermal growth factor receptor tyrosine kinase inhibitor.Phase II Trial of Erlotinib during and after Radiotherapy in Children with Newly Diagnosed High-Grade Gliomas.Treatment of posterior fossa tumors in children.Antiangiogenic therapy and mechanisms of tumor resistance in malignant glioma.Clinical pharmacokinetics of tyrosine kinase inhibitors: focus on 4-anilinoquinazolines.Treatment of high-grade glioma in children and adolescents.Paediatric and adult malignant glioma: close relatives or distant cousins?Erlotinib: early clinical development in brain cancer.Commentary on: "A Multi-Institutional Experience in Pediatric High Grade Glioma".Ultra High Performance Liquid Chromatography Method for the Determination of Two Recently FDA Approved TKIs in Human Plasma Using Diode Array Detection.GATA2 promotes glioma progression through EGFR/ERK/Elk-1 pathway.Pathological significance of epidermal growth factor receptor expression and amplification in human gliomas.Adverse Renal Effects of Novel Molecular Oncologic Targeted Therapies: A Narrative Review.TKI combination therapy: strategy to enhance dasatinib uptake by inhibiting Pgp- and BCRP-mediated efflux.

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Phase I and pharmacokinetic studies of erlotinib administered concurrently with radiotherapy for children, adolescents, and young adults with high-grade glioma.

http://www.wikidata.org/entity/Q37069238

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on January 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Phase I and pharmacokinetic st ...... adults with high-grade glioma.

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Phase I and pharmacokinetic st ...... adults with high-grade glioma.

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type

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Phase I and pharmacokinetic st ...... adults with high-grade glioma.

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Phase I and pharmacokinetic st ...... adults with high-grade glioma.

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Phase I and pharmacokinetic st ...... adults with high-grade glioma.

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Phase I and pharmacokinetic st ...... adults with high-grade glioma.

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1078-0432.CCR-08-1923

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Clinical Cancer Research

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Phase I and pharmacokinetic st ...... adults with high-grade glioma

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Alberto Broniscer

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Amar Gajjar

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Clinton F Stewart

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David W Ellison

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E Brannon Morris

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Fred H Laningham

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Paula Schaiquevich

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Suzanne J Baker

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Thomas E Merchant

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P2860

Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I. Introduction and design

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy.

Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain

High frequency of mutations of the PIK3CA gene in human cancers

Phase II clinical trial data with the epidermal growth factor receptor tyrosine kinase inhibitor erlotinib (OSI-774) in non-small-cell lung cancer.

Temozolomide in malignant gliomas of childhood: a United Kingdom Children's Cancer Study Group and French Society for Pediatric Oncology Intergroup Study.

Phase II trial of temozolomide in children with recurrent high-grade glioma.

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701-707

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10.1158/1078-0432.CCR-08-1923

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2

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Raelene Endersby

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2009-01-01T00:00:00Z

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19147777

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radiation therapy

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2629527

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