Intermittent hypoxia and stem cell implants preserve breathing capacity in a rodent model of amyotrophic lateral sclerosis
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Hypoxia-induced phrenic long-term facilitation: emergent propertiesUnexpected benefits of intermittent hypoxia: enhanced respiratory and nonrespiratory motor functionSystemic injection of AAV9-GDNF provides modest functional improvements in the SOD1G93A ALS rat but has adverse side effects.Neither serotonin nor adenosine-dependent mechanisms preserve ventilatory capacity in ALS ratsHuman induced pluripotent stem cells are a novel source of neural progenitor cells (iNPCs) that migrate and integrate in the rodent spinal cord.Spinal but not cortical microglia acquire an atypical phenotype with high VEGF, galectin-3 and osteopontin, and blunted inflammatory responses in ALS rats.The polymorphic and contradictory aspects of intermittent hypoxiaTherapeutic potential of intermittent hypoxia: a matter of dose.Human neural stem cell transplantation in ALS: initial results from a phase I trial.Intermittent Hypoxia-Induced Spinal Inflammation Impairs Respiratory Motor Plasticity by a Spinal p38 MAP Kinase-Dependent MechanismRespiratory function after selective respiratory motor neuron death from intrapleural CTB-saporin injectionsPhrenic long-term facilitation requires PKCθ activity within phrenic motor neurons.Stimulation of Respiratory Motor Output and Ventilation in a Murine Model of Pompe Disease by Ampakines.Repetitive acute intermittent hypoxia does not promote generalized inflammatory gene expression in the rat CNS.Severe respiratory changes at end stage in a FUS-induced disease state in adult rats.Acute intermittent hypoxia induced phrenic long-term facilitation despite increased SOD1 expression in a rat model of ALS.Intermittent hypoxia and neurorehabilitation.Quantitative assessment of integrated phrenic nerve activity.The therapeutic potential of IGF-I in skeletal muscle repair.Synergistic effects of GDNF and VEGF on lifespan and disease progression in a familial ALS rat modelSustained Hypoxia Elicits Competing Spinal Mechanisms of Phrenic Motor Facilitation.In Vivo Tracking of Human Neural Progenitor Cells in the Rat Brain Using Magnetic Resonance Imaging Is Not Enhanced by Ferritin Expression.Repeated intravenous doxapram induces phrenic motor facilitation.Repetitive acute intermittent hypoxia increases growth/neurotrophic factor expression in non-respiratory motor neuronsVentilatory control in ALS.Common mechanisms of compensatory respiratory plasticity in spinal neurological disorders.Acute intermittent hypoxia induced neural plasticity in respiratory motor control.The respiratory neuromuscular system in Pompe disease.Glial cell line-derived neurotrophic factor-secreting human neural progenitors show long-term survival, maturation into astrocytes, and no tumor formation following transplantation into the spinal cord of immunocompromised rats.Stem cells therapy for ALS.A Subsequent Human Neural Progenitor Transplant into the Degenerate Retina Does Not Compromise Initial Graft Survival or Therapeutic Efficacy.Update in sleep medicine 2013.Human Neural Progenitor Transplantation Rescues Behavior and Reduces α-Synuclein in a Transgenic Model of Dementia with Lewy Bodies.Mechanisms of Enhanced Phrenic Long-Term Facilitation in SOD1G93A Rats.Compensatory plasticity in diaphragm and intercostal muscle utilization in a rat model of ALS.Phrenic long-term facilitation following intrapleural CTB-SAP-induced respiratory motor neuron death.Intermittent Hypoxia Enhances Functional Connectivity of Midcervical Spinal Interneurons.Inducible Expression of GDNF in Transplanted iPSC-Derived Neural Progenitor Cells.Restrictive Lung Disease in the Cu/Zn Superoxide-Dismutase 1 G93A Amyotrophic Lateral Sclerosis Mouse Model.Hypoglossal Motor Neuron Death Via Intralingual CTB-saporin (CTB-SAP) Injections Mimic Aspects of Amyotrophic Lateral Sclerosis (ALS) Related to Dysphagia
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Intermittent hypoxia and stem cell implants preserve breathing capacity in a rodent model of amyotrophic lateral sclerosis
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 06 December 2012
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Intermittent hypoxia and stem ...... amyotrophic lateral sclerosis
@en
Intermittent hypoxia and stem ...... amyotrophic lateral sclerosis.
@nl
type
label
Intermittent hypoxia and stem ...... amyotrophic lateral sclerosis
@en
Intermittent hypoxia and stem ...... amyotrophic lateral sclerosis.
@nl
prefLabel
Intermittent hypoxia and stem ...... amyotrophic lateral sclerosis
@en
Intermittent hypoxia and stem ...... amyotrophic lateral sclerosis.
@nl
P2093
P2860
P921
P1476
Intermittent hypoxia and stem ...... amyotrophic lateral sclerosis
@en
P2093
Clive N Svendsen
Erica A Dale
Genevieve Gowing
Gordon S Mitchell
Jacalyn McHugh
Lisa J Nashold
Masatoshi Suzuki
Nicole L Nichols
Pablo Avalos
P2860
P304
P356
10.1164/RCCM.201206-1072OC
P407
P577
2012-12-06T00:00:00Z