Myeloid-specific expression of Api6/AIM/Sp alpha induces systemic inflammation and adenocarcinoma in the lung
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Establishment of lal-/- myeloid lineage cell line that resembles myeloid-derived suppressive cellsApi6/AIM/Spα/CD5L overexpression in alveolar type II epithelial cells induces spontaneous lung adenocarcinomaStat3 downstream gene product chitinase 3-like 1 is a potential biomarker of inflammation-induced lung cancer in multiple mouse lung tumor models and humans.The scavenger protein apoptosis inhibitor of macrophages (AIM) potentiates the antimicrobial response against Mycobacterium tuberculosis by enhancing autophagy.Critical roles of lysosomal acid lipase in myelopoiesis.Myeloid-derived suppressor cells are involved in lysosomal acid lipase deficiency-induced endothelial cell dysfunctions.A novel nanoparticle drug delivery system: the anti-inflammatory activity of curcumin is enhanced when encapsulated in exosomesIntegration of transcriptomics and metabonomics: improving diagnostics, biomarker identification and phenotyping in ulcerative colitis.Gene profile of myeloid-derived suppressive cells from the bone marrow of lysosomal acid lipase knock-out mice.Activation of mTOR pathway in myeloid-derived suppressor cells stimulates cancer cell proliferation and metastasis in lal(-/-) miceListeria monocytogenes infection induces prosurvival metabolic signaling in macrophages.Overexpression of dominant negative peroxisome proliferator-activated receptor-γ (PPARγ) in alveolar type II epithelial cells causes inflammation and T-cell suppression in the lung.Matrix metalloproteinase 12 overexpression in myeloid lineage cells plays a key role in modulating myelopoiesis, immune suppression, and lung tumorigenesis.Myeloid-specific expression of human lysosomal acid lipase corrects malformation and malfunction of myeloid-derived suppressor cells in lal-/- miceSignal transducer and activator of transcription 3 (Stat3C) promotes myeloid-derived suppressor cell expansion and immune suppression during lung tumorigenesis.Inhibition of PPARγ in myeloid-lineage cells induces systemic inflammation, immunosuppression, and tumorigenesis.The human CD5L/AIM-CD36 axis: A novel autophagy inducer in macrophages that modulates inflammatory responses.Interaction of AIM with insulin-like growth factor-binding protein-4.Critical role of PPARγ in myeloid-derived suppressor cell-stimulated cancer cell proliferation and metastasis.Matrix metalloproteinase 12 overexpression in lung epithelial cells plays a key role in emphysema to lung bronchioalveolar adenocarcinoma transition.Critical role of the mTOR pathway in development and function of myeloid-derived suppressor cells in lal-/- mice.Lysosomal acid lipase in mesenchymal stem cell stimulation of tumor growth and metastasis.Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function.Negative regulation of myeloid-derived suppressor cells in cancer.Tumor microenvironment and myeloid-derived suppressor cells.Impacts of the apoptosis inhibitor of macrophage (AIM) on obesity-associated inflammatory diseases.Myeloid-derived suppressor cells in immunity and autoimmunity.AIM/CD5L: a key protein in the control of immune homeostasis and inflammatory disease.Hepatocyte-Specific Expression of Human Lysosome Acid Lipase Corrects Liver Inflammation and Tumor Metastasis in lal(-/-) Mice.Myeloid-derived suppressor cells interact with tumors in terms of myelopoiesis, tumorigenesis and immunosuppression: thick as thieves.Lung Epithelial Cell-Specific Expression of Human Lysosomal Acid Lipase Ameliorates Lung Inflammation and Tumor Metastasis in Lipa(-/-) MiceMyeloid-specific expression of Stat3C results in conversion of bone marrow mesenchymal stem cells into alveolar type II epithelial cells in the lung.CD5L Promotes M2 Macrophage Polarization through Autophagy-Mediated Upregulation of ID3.
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Myeloid-specific expression of Api6/AIM/Sp alpha induces systemic inflammation and adenocarcinoma in the lung
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on February 2009
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Myeloid-specific expression of ...... and adenocarcinoma in the lung
@en
Myeloid-specific expression of ...... nd adenocarcinoma in the lung.
@nl
type
label
Myeloid-specific expression of ...... and adenocarcinoma in the lung
@en
Myeloid-specific expression of ...... nd adenocarcinoma in the lung.
@nl
prefLabel
Myeloid-specific expression of ...... and adenocarcinoma in the lung
@en
Myeloid-specific expression of ...... nd adenocarcinoma in the lung.
@nl
P2093
P2860
P1476
Myeloid-specific expression of ...... and adenocarcinoma in the lung
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P2093
P2860
P304
P356
10.4049/JIMMUNOL.182.3.1648
P407
P577
2009-02-01T00:00:00Z