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Regulation of cell signaling and apoptosis by tumor suppressor WWOX.

Regulation of cell signaling and apoptosis by tumor suppressor WWOX.

http://www.wikidata.org/entity/Q37071049

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Tumor Suppressor WWOX Contributes to the Elimination of Tumorigenic Cells in Drosophila melanogaster Functional genetic variant of WW domain-containing oxidoreductase (WWOX) gene is associated with hepatocellular carcinoma risk.WWOX CNV-67048 Functions as a Risk Factor for Epithelial Ovarian Cancer in Chinese Women by Negatively Interacting with Oral Contraceptive Use.Hyaluronan activates Hyal-2/WWOX/Smad4 signaling and causes bubbling cell death when the signaling complex is overexpressed.Common genetic variation drives molecular heterogeneity in human iPSCs.Association of WWOX rs9926344 polymorphism with poor prognosis of hepatocellular carcinoma.Relationship of genetic variant distributions of WW domain-containing oxidoreductase gene with uterine cervical cancer.

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Regulation of cell signaling and apoptosis by tumor suppressor WWOX.

http://www.wikidata.org/entity/Q37071049

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 16 January 2015

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Regulation of cell signaling and apoptosis by tumor suppressor WWOX.

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Regulation of cell signaling and apoptosis by tumor suppressor WWOX.

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type

label

Regulation of cell signaling and apoptosis by tumor suppressor WWOX.

@en

Regulation of cell signaling and apoptosis by tumor suppressor WWOX.

@nl

prefLabel

Regulation of cell signaling and apoptosis by tumor suppressor WWOX.

@en

Regulation of cell signaling and apoptosis by tumor suppressor WWOX.

@nl

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Experimental Biology and Medicine

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Regulation of cell signaling and apoptosis by tumor suppressor WWOX.

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Feng-Jie Lai

http://www.w3.org/2001/XMLSchema#string

Jui-Yen Lo

http://www.w3.org/2001/XMLSchema#string

Li-Jin Hsu

http://www.w3.org/2001/XMLSchema#string

Ying-Tsen Chou

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P2860

Zfra affects TNF-mediated cell death by interacting with death domain protein TRADD and negatively regulates the activation of NF-kappaB, JNK1, p53 and WOX1 during stress response

WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer

Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells

WW domain-containing proteins, WWOX and YAP, compete for interaction with ErbB-4 and modulate its transcriptional function

Inhibition of the Wnt/beta-catenin pathway by the WWOX tumor suppressor protein

Transforming growth factor beta1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1

WWOX binds the specific proline-rich ligand PPXY: identification of candidate interacting proteins

WWOX: a candidate tumor suppressor gene involved in multiple tumor types

Functional association between Wwox tumor suppressor protein and p73, a p53 homolog

Fragile histidine triad protein, WW domain-containing oxidoreductase protein Wwox, and activator protein 2gamma expression levels correlate with basal phenotype in breast cancer

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383-391

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scholarly article

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10.1177/1535370214566747

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3

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25595191

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apoptotic process

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4935227

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