Mitochondrial translocation of cofilin is required for allyl isothiocyanate-mediated cell death via ROCK1/PTEN/PI3K signaling pathway.

Mitochondrial translocation of cofilin is required for allyl isothiocyanate-mediated cell death via ROCK1/PTEN/PI3K signaling pathway.

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http://www.wikidata.org/entity/Q37071666
RhoA/ROCK/PTEN signaling is involved in AT-101-mediated apoptosis in human leukemia cells in vitro and in vivo.Novel roles for actin in mitochondrial fissionROCK1 as a novel prognostic marker in vulvar cancerTransient assembly of F-actin on the outer mitochondrial membrane contributes to mitochondrial fission.Mitochondrial translocation and interaction of cofilin and Drp1 are required for erucin-induced mitochondrial fission and apoptosis.Hsa-miR-146a-5p modulates androgen-independent prostate cancer cells apoptosis by targeting ROCK1.Dephosphorylation and mitochondrial translocation of cofilin sensitizes human leukemia cells to cerulenin-induced apoptosis via the ROCK1/Akt/JNK signaling pathwayTriptolide induces apoptosis in human leukemia cells through caspase-3-mediated ROCK1 activation and MLC phosphorylation.Cucurbitacin B exerts anti-cancer activities in human multiple myeloma cells in vitro and in vivo by modulating multiple cellular pathways.Phosphorylation of cofilin-1 by ERK confers HDAC inhibitor resistance in hepatocellular carcinoma cells via decreased ROS-mediated mitochondria injury.Anti-cancer effect of ursolic acid activates apoptosis through ROCK/PTEN mediated mitochondrial translocation of cofilin-1 in prostate cancer.Cofilin1-dependent actin dynamics control DRP1-mediated mitochondrial fission.Identification and Characterization of Key Charged Residues in the Cofilin Protein Involved in Azole Susceptibility, Apoptosis, and Virulence of Aspergillus fumigatus.Cofilin-2 Acts as a Marker for Predicting Radiotherapy Response and Is a Potential Therapeutic Target in Nasopharyngeal Carcinoma.Hirsutine induces mPTP-dependent apoptosis through ROCK1/PTEN/PI3K/GSK3β pathway in human lung cancer cells.In renal cell carcinoma the PTEN splice variant PTEN-Δ shows similar function as the tumor suppressor PTEN itself.MicroRNA-217 functions as a tumor suppressor in cervical cancer cells through targeting Rho-associated protein kinase 1
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Mitochondrial translocation of cofilin is required for allyl isothiocyanate-mediated cell death via ROCK1/PTEN/PI3K signaling pathway.

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http://www.wikidata.org/entity/Q37071666
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on 29 July 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Mitochondrial translocation of ...... 1/PTEN/PI3K signaling pathway.
@en
Mitochondrial translocation of ...... 1/PTEN/PI3K signaling pathway.
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type
label
Mitochondrial translocation of ...... 1/PTEN/PI3K signaling pathway.
@en
Mitochondrial translocation of ...... 1/PTEN/PI3K signaling pathway.
@nl
prefLabel
Mitochondrial translocation of ...... 1/PTEN/PI3K signaling pathway.
@en
Mitochondrial translocation of ...... 1/PTEN/PI3K signaling pathway.
@nl
P1433
P1476
P2093
P2860
P2888
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P5875
P6179
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Mitochondrial translocation of ...... 1/PTEN/PI3K signaling pathway.
@en
P2093
P2860
P2888
P304
P31
P356
P478
P577
P5875
P6179
P698
P921
P932