Activity of 8F4, a T-cell receptor-like anti-PR1/HLA-A2 antibody, against primary human AML in vivo
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Cathepsin G is broadly expressed in acute myeloid leukemia and is an effective immunotherapeutic target.Neuropilin-1 mediates neutrophil elastase uptake and cross-presentation in breast cancer cells.A novel TCR-like CAR with specificity for PR1/HLA-A2 effectively targets myeloid leukemia in vitro when expressed in human adult peripheral blood and cord blood T cellsPR1-specific cytotoxic T lymphocytes are relatively frequent in umbilical cord blood and can be effectively expanded to target myeloid leukemia.The progress and current status of immunotherapy in acute myeloid leukemia.Targeting PR1 in myeloid leukemia.RosettaAntibodyDesign (RAbD): A general framework for computational antibody design.Serine Proteases Enhance Immunogenic Antigen Presentation on Lung Cancer Cells.Therapeutic Antibodies for Myeloid Neoplasms-Current Developments and Future Directions.
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Activity of 8F4, a T-cell receptor-like anti-PR1/HLA-A2 antibody, against primary human AML in vivo
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 08 March 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Activity of 8F4, a T-cell rece ...... inst primary human AML in vivo
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Activity of 8F4, a T-cell rece ...... nst primary human AML in vivo.
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Activity of 8F4, a T-cell rece ...... inst primary human AML in vivo
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Activity of 8F4, a T-cell rece ...... nst primary human AML in vivo.
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Activity of 8F4, a T-cell rece ...... inst primary human AML in vivo
@en
Activity of 8F4, a T-cell rece ...... nst primary human AML in vivo.
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Activity of 8F4, a T-cell rece ...... inst primary human AML in vivo
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A Sergeeva
J J Molldrem
K Clise-Dwyer
K Ruisaard
P Sukhumalchandra
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10.1038/LEU.2016.57
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2016-03-08T00:00:00Z
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1023463208