The calcineurin/NFAT signaling pathway: a novel therapeutic target in leukemia and solid tumors.
about
Nuclear Raf-1 kinase regulates the CXCR5 promoter by associating with NFATc3 to drive retinoic acid-induced leukemic cell differentiationCHP2 activates the calcineurin/nuclear factor of activated T cells signaling pathway and enhances the oncogenic potential of HEK293 cellsRegulation of immune cell development through soluble inositol-1,3,4,5-tetrakisphosphateCell cycle and apoptosis regulation by NFAT transcription factors: new roles for an old playerFrom Drosophila to humans: reflections on the roles of the prolyl isomerases and chaperones, cyclophilins, in cell function and diseaseMicroRNA and transcription factor co-regulatory network analysis reveals miR-19 inhibits CYLD in T-cell acute lymphoblastic leukemiaConstruction of a novel oligonucleotide array-based transcription factor interaction assay platform and its uses for profiling STAT1 cofactors in mouse fibroblast cellsHeart-specific deletion of CnB1 reveals multiple mechanisms whereby calcineurin regulates cardiac growth and function.Gene set analysis exploiting the topology of a pathway.The Drosophila STIM1 orthologue, dSTIM, has roles in cell fate specification and tissue patterning.Striking the target in Wnt-y conditions: intervening in Wnt signaling during cancer progressionWnt/Ca2+/NFAT signaling maintains survival of Ph+ leukemia cells upon inhibition of Bcr-Abl.An epigenetic chromatin remodeling role for NFATc1 in transcriptional regulation of growth and survival genes in diffuse large B-cell lymphomas.Wnt signaling in estrogen-induced lactotroph proliferation.Wnt4 induces nephronic tubules in metanephric mesenchyme by a non-canonical mechanism.Components of the canonical and non-canonical Wnt pathways are not mis-expressed in pituitary tumorsAn overview of notch signaling in adult tissue renewal and maintenance.Screening for a gene deletion mutant whose temperature sensitivity is suppressed by FK506 in budding yeast and its application for a positive screening for drugs inhibiting calcineurin.Ca2+-calcineurin signaling is involved in norepinephrine-induced cardiac fibroblasts activation.CaMKII plays a part in the chondrogenesis of bone marrow-derived mesenchymal stem cells.Regulatory subunit myristoylation antagonizes calcineurin phosphatase activation in yeastNFAT2 Isoforms Differentially Regulate Gene Expression, Cell Death, and Transformation through Alternative N-Terminal Domains.NFAT as cancer target: mission possible?Nuclear Factor of Activated T Cells-dependent Down-regulation of the Transcription Factor Glioma-associated Protein 1 (GLI1) Underlies the Growth Inhibitory Properties of Arachidonic Acid.Gene expression analyses of primary melanomas reveal CTHRC1 as an important player in melanoma progression.Hairy cell leukemia in kidney transplantation: lesson from a rare disorder.STIM proteins: integrators of signalling pathways in development, differentiation and disease.Macrophages mediate a switch between canonical and non-canonical Wnt pathways in canine mammary tumors.Insights to transcriptional networks by using high throughput RNAi strategies.Targeting TRPC6 channels in oesophageal carcinoma growth.Overview on HTLV-1 p12, p8, p30, p13: accomplices in persistent infection and viral pathogenesisThe many lives of CTIP2: from AIDS to cancer and cardiac hypertrophy.Does therapeutic intervention in atopic dermatitis normalize epidermal Notch deficiency?WNT signaling in glioblastoma and therapeutic opportunities.NFATc2 is an intrinsic regulator of melanoma dedifferentiation.Coordinate activities of BRD4 and CDK9 in the transcriptional elongation complex are required for TGFβ-induced Nox4 expression and myofibroblast transdifferentiation.The role of nuclear factor of activated T cells in pulmonary arterial hypertension.The 'N-factors' in pancreatic cancer: functional relevance of NF-κB, NFAT and Nrf2 in pancreatic cancer.Sequential activation of NFAT and c-Myc transcription factors mediates the TGF-beta switch from a suppressor to a promoter of cancer cell proliferation.NFAT signalling is a novel target of oncogenic BRAF in metastatic melanoma.
P2860
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P2860
The calcineurin/NFAT signaling pathway: a novel therapeutic target in leukemia and solid tumors.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
The calcineurin/NFAT signaling ...... in leukemia and solid tumors.
@en
The calcineurin/NFAT signaling ...... in leukemia and solid tumors.
@nl
type
label
The calcineurin/NFAT signaling ...... in leukemia and solid tumors.
@en
The calcineurin/NFAT signaling ...... in leukemia and solid tumors.
@nl
prefLabel
The calcineurin/NFAT signaling ...... in leukemia and solid tumors.
@en
The calcineurin/NFAT signaling ...... in leukemia and solid tumors.
@nl
P356
P1433
P1476
The calcineurin/NFAT signaling ...... in leukemia and solid tumors.
@en
P2093
Jacques Ghysdael
P304
P356
10.4161/CC.7.3.5357
P50
P577
2007-11-23T00:00:00Z