Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis
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From bending DNA to diabetes: the curious case of HMGA1Nonalcoholic fatty liver disease: a comprehensive review of a growing epidemicNaringenin prevents dyslipidemia, apolipoprotein B overproduction, and hyperinsulinemia in LDL receptor-null mice with diet-induced insulin resistanceGenetic Rodent Models of Obesity-Associated Ovarian Dysfunction and Subfertility: Insights into Polycystic Ovary SyndromeLiver fibrosis in human immunodeficiency virus/hepatitis C virus coinfection: Diagnostic methods and clinical impact.Does Diacylglycerol Accumulation in Fatty Liver Disease Cause Hepatic Insulin Resistance?Pathway-selective insulin resistance and metabolic disease: the importance of nutrient fluxLessons from mouse models of high-fat diet-induced NAFLDPathogenesis of the metabolic syndrome: insights from monogenic disordersHow Useful Are Monogenic Rodent Models for the Study of Human Non-Alcoholic Fatty Liver Disease?Nonalcoholic fatty liver disease - A multisystem disease?Cdc2-like kinase 2 is an insulin-regulated suppressor of hepatic gluconeogenesisImpaired-inactivation of FoxO1 contributes to glucose-mediated increases in serum very low-density lipoproteinE4orf1: a novel ligand that improves glucose disposal in cell cultureHuman biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression.Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesisMutations disrupting the Kennedy phosphatidylcholine pathway in humans with congenital lipodystrophy and fatty liver diseaseHepatic Diacylglycerol-Associated Protein Kinase Cε Translocation Links Hepatic Steatosis to Hepatic Insulin Resistance in Humans.Mice deficient in group VIB phospholipase A2 (iPLA2gamma) exhibit relative resistance to obesity and metabolic abnormalities induced by a Western diet.Treatment of type B insulin resistance: a novel approach to reduce insulin receptor autoantibodies.Hypomorphism in human NSMCE2 linked to primordial dwarfism and insulin resistance.Genetic defects in human pericentrin are associated with severe insulin resistance and diabetes.Nonalcoholic Fatty liver disease: pathogenesis and therapeutics from a mitochondria-centric perspective.Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independent of obesity.Mendelian randomization studies do not support a role for raised circulating triglyceride levels influencing type 2 diabetes, glucose levels, or insulin resistance.Human lipodystrophies: genetic and acquired diseases of adipose tissue.Genetic determinants of hepatic steatosis in man.Founder effect in the Horn of Africa for an insulin receptor mutation that may impair receptor recyclingTemplate to improve glycemic control without reducing adiposity or dietary fat.Mitochondrial dysfunction in patients with primary congenital insulin resistance.Coinfection with HIV-1 and HCV--a one-two punch.Genetics in endocrinology: genetic forms of severe insulin resistance: what endocrinologists should know.Flavin-containing monooxygenase 3 as a potential player in diabetes-associated atherosclerosis.Low circulating levels of IGF-1 in healthy adults are associated with reduced β-cell function, increased intramyocellular lipid, and enhanced fat utilization during fasting.Human fatty liver disease: old questions and new insightsPathogenesis of selective insulin resistance in isolated hepatocytes.Prevalence of prediabetes and diabetes and metabolic profile of patients with nonalcoholic fatty liver disease (NAFLD).Mechanistic insights revealed by lipid profiling in monogenic insulin resistance syndromes.The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humansSevere insulin resistance and hypertriglyceridemia after childhood total body irradiation.
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P2860
Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 26 January 2009
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis
@en
Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis.
@nl
type
label
Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis
@en
Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis.
@nl
prefLabel
Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis
@en
Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis.
@nl
P2093
P2860
P50
P356
P1476
Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis
@en
P2093
Alessandra Vottero
Claire A Adams
Dipak Kanabar
Elaine K Cochran
Maria A Soos
Paul Durrington
Peter R Murgatroyd
Phillip Gorden
Sarah Jackson
P2860
P304
P356
10.1172/JCI37432
P407
P577
2009-01-26T00:00:00Z